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检索条件"主题词=Viral replication"
32 条 记 录,以下是1-10 订阅
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Sumoylation of Human Parainfluenza Virus Type 3 Phosphoprotein Correlates with A Reduction in viral replication
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Virologica Sinica 2021年 第3期36卷 438-448页
作者: Qi Cheng Wenjing Huai Xiaoyan Wu Mingzhou Chen State Key Laboratory of Virology Modem Virology Research CenterCollege of Life SciencesWuhan UniversityWuhan 430072China
Human parainfluenza virus type 3(HPIV3), a member of the Paramyxoviridae family, can cause lower respiratory disease in infants and young children. The phosphoprotein(P) of HPIV3 is an essential cofactor of the viral ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Ebola virus VP35 perturbs type I interferon signaling to facilitate viral replication
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Virologica Sinica 2023年 第6期38卷 922-930页
作者: Zengguo Cao Chenchen Liu Cheng Peng Yong Ran Yulin Yao Gengfu Xiao Entao Li Zixi Chen Xia Chuai Sandra Chiu Key Laboratory of Special Pathogens and Biosafety Wuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhan430071China University of Chinese Academy of Sciences Beijing100190China National Biosafety Laboratory Chinese Academy of SciencesWuhan430020China Division of Life Sciences and Medicine University of Science and Technology of Chin1Hefei230026China Shenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science Shenzhen Engineering Laboratory for Marine Algal BiotechnologyGuangdong Provincial Key Laboratory for Plant EpigeneticsCollege of Life Sciences and OceanographyShenzhen UniversityShenzhen 518060China
As one of the deadliest viruses,Ebola virus(EBOV)causes lethal hemorrhagic fevers in humans and nonhuman *** suppression of innate immunity leads to robust systemic virus replication of EBOV,leading to enhanced ***,th... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Naturally occurring PA^(E206K)point mutation in 2009 H1N1 pandemic influenza viruses impairs viral replication at high temperatures
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Virologica Sinica 2024年 第1期39卷 71-80页
作者: Mengmeng Cao Qiannan Jia Jinghua Li Lili Zhao Li zhu Yufan Zhang Shan Li Tao Deng National Institute of Pathogen Biology Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing100730China CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing100101China
The emergence of influenza virus A pandemic H1N1 in April 2009 marked the first pandemic of the 21st *** this study,we observed significant differences in the polymerase activities of two clinical 2009 H1N1 influenza ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Melanization induced by Heliothis virescens ascovirus 3h promotes viral replication
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Insect Science 2021年 第2期28卷 472-484页
作者: Zi-Qi Li Xiao-Hui Song Min Wang Shu Wang Guo-Hua Huang Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests Hunan Agricultural UniversityChangshaChina College of Plant Protection Hunan Agricultural UniversityChangshaChina
Melanization is an important innate immune defense mechanism of insects,which can kill invading *** pathogens,for their survival and reproduction,inhibit the melanization of the ***,our results suggested that after in... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Frequency of viral replication Markers in Chronic HBV Carriers in N’Djamena, Chad
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Open Journal of Gastroenterology 2022年 第10期12卷 271-277页
作者: Ali Mahamat Moussa Mayanna Habkreo Adawaye Chatté Borde Emmanuel Adoum Abdelrazack Fouda Bessimbaye Nadlaou Service de Médecine Interne et Gastroentérologie CHU La Référence Nationale de N’Djamena N’Djamena Tchad Département des Sciences Biomédicales et Pharmaceutiques Faculté des Sciences de la Santé Humaine Université de N’Djamena N’Djamena Tchad Programme National de Lutte Contre le VIH/IST/Hépatite Ministère de la Santé Publique N’Djamena Tchad
Introduction: According to the WHO, Chad is located in an area of high endemicity for hepatitis B virus (HBV). The aim of this study was to analyze the virological profiles of chronic HBV carriers. Materials and Metho... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
RIG-1 and MDA-5 signaling pathways contribute to IFN-β production and viral replication in Porcine circovirus virus type 2 infection cells
RIG-1 and MDA-5 signaling pathways contribute to IFN-β prod...
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中国兽医病理学2017年学术研讨会暨兽医病理学分会第九次全国会员代表大会
作者: Bei Huang Jiansheng Li Xinchen Zhang Qiling Zhao Mingqing Lu Yingjun Lv College of veterinary science Nanjing agricultural university
Interferon(IFN) is known for its antiviral ***,it is surprising that treatment of IFN-α and IFN-β in vitro enhanced replication of porcine circovirus type 2(PCV2),indicating that complex relationship between interfe... 详细信息
来源: cnki会议 评论
Corilagin inhibits SARS-CoV-2 replication by targeting viral RNA-dependent RNA polymerase
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Acta Pharmaceutica Sinica B 2021年 第6期11卷 1555-1567页
作者: Quanjie Li Dongrong Yi Xiaobo Lei Jianyuan Zhao Yongxin Zhang Xiangling Cui Xia Xiao Tao Jiao Xiaojing Dong Xuesen Zhao Hui Zeng Chen Liang Lili Ren Fei Guo Xiaoyu Li Jianwei Wang Shan Cen Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences and Peking Union Medical SchoolBeijing 100050China Institute of Pathogen Biology Chinese Academy of Medical Sciences and Peking Union Medical SchoolBeijing 100730China Institute of Infectious Disease Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Lady Davis Institute Jewish General HospitalMc Gill UniversityMontrealQuebec H3T 1E2Canada CAMS Key Laboratory of Antiviral Drug Research Peking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China
Severe acute respiratory syndrome coronavirus-2(SARS-CoV-2) has become one major threat to human population *** RNA-dependent RNA polymerase(RdRp) presents an ideal target of antivirals,whereas nucleoside analogs inhi... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
In vitro inhibition of HIV-1 replication in autologous CD4*T cells indicates viral containment by multifactorial mechanisms
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Virologica Sinica 2017年 第6期32卷 485-494页
作者: Ting Tu Jianbo Zhan Danlei Mou Wei Li Bin Su Tong Zhang Tao Li Ning Li Hao Wu Cong Jin Huabiao Chen Jiangsu Key Laboratory of Clinical Laboratory Medicine Jiangsu University School of MedicineZhenjiang 212013China National HIV/HCV Reference Laboratory National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China Hubei Provincial Center for Disease Control and Prevention Wuhan 430079China Beijing You'an Hospital Capital Medical UniversityBeijing 100069China
HIV-1-specific cytotoxic T lymphocytes(CTLs) and neutralizing antibodies(NAbs) are present during chronic infection, but the relative contributions of these effector mechanisms to viral containment remain unclear. Her... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Ciclopirox inhibits SARS-CoV-2 replication by promoting the degradation of the nucleocapsid protein
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Acta Pharmaceutica Sinica B 2024年 第6期14卷 2505-2519页
作者: Xiafei Wei Yuzheng Zhou Xiaotong Shen Lujie Fan Donglan Liu Xiang Gao Jian Zhou Yezi Wu Yunfei Li Wei Feng Zheng Zhang Institute for Hepatology National Clinical Research Center for Infectious DiseaseShenzhen Third People's HospitalSouthern University of Science and TechnologyShenzhen 518112China Guangzhou Laboratory Guangzhou Medical UniversityGuangzhou 511495China State Key Laboratory of Respiratory Disease National Clinical Research Center for Respiratory DiseaseGuangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120China
The nucleocapsid protein(NP)plays a crucial role in SARS-CoV-2 replication and is the most abundant structural protein with a long *** its vital role in severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)assem... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
LncRNA NKILA inhibits HBV replication by repressing NF-κB signalling activation
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Virologica Sinica 2024年 第1期39卷 44-55页
作者: Xi Zhang Yuanyuan Li Chen Huan Yubao Hou Rujia Liu Hongyun Shi Peng Zhang Baisong Zheng Yingchao Wang Hong Wang Wenyan Zhang Institute of Virology and AIDS Research The First Hospital of Jilin UniversityChangchun130012China Department of Ophthalmology The First Hospital of Jilin UniversityChangchun130012China Hepatobiliary Pancreatic Surgery The First Hospital of Jilin UniversityChangchun130012China
Hepatitis B virus(HBV)infection results in liver cirrhosis and hepatocellular carcinoma(HCC).HBx/nuclear factor(NF)-κB pathway plays a role in HBV ***,whether NF-κB-interacting long noncoding RNA(NKILA),a suppressor... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论