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Non-invasive physical therapy as salvage measure for ischemic skin flap:A literature review

World Journal of Clinical Cases 2021年第14期9卷 3227-3237页

作者： Yin-Hua Zheng Li-Quan Yin Hai-Kun Xu Xu Gong Department of Hand and Foot Surgery The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Rehabilitation Medicine The Third Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Radiology China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

This review focuses on the available evidence regarding the molecular mechanisms and treatment potential of several non-surgical physical therapies for managing flap ischemia to propose a non-invasive,economical,and simple treatment to improve flap survival.A review of the literature was conducted on the topics of various non-invasive methods for the treatment of ischemic necrosis of the distal end of the flap between 1988 and 2019.A total of 52 published studies were reviewed on the applications of hyperbaric oxygen therapy,electrical stimulation therapy,heat stress pretreatment,phototherapy,and vibration therapy to manage skin flap *** underlying molecular mechanisms of these physical therapies on revitalizing the dying skin flaps were discussed and preliminary clinical uses of these therapies to salvage the necrotic skin flaps were pooled and summarized for clarifying the safety and feasibility of these *** physical therapy regimens have been ushered to manage necrotic development in cutaneous *** the refinement of these new technologies and enhancement of related basic science research on vascular revitalization,the prevention and treatment of flap ischemia will enter a new era.

关键词： Physiotherapy Skin flap Hyperbaric oxygen Electrical stimulation therapy Heat stress pretreatment Phototherapy vibration therapy

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Design of a Biomedical Device to Reduce Anxiety Experienced by Patients Diagnosed with Parkinson’s Disease

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Journal of Biomedical Science and Engineering 2024年第3期17卷 57-71页

作者： Madhini Vigneswaran Anjali Menon Research Department MEDIC Foundation Vancouver Canada

Parkinson’s disease (PD) is a neurodegenerative disease that occurs due to loss of nerve cells that produce dopamine in the brain, affecting approximately 4 million people worldwide. PD patients often feel an increase in anxiety levels daily. While there are medications/exercises to help relieve anxiety, there are limited methods to reduce anxiety without the help of a caretaker. As a result, MEDIC Foundation, a non-profit organization in British Columbia, Canada, is designing an automated system that consists of a wristband and an application which uses vi-bration therapy to help reduce anxiety of PD patients. Literature reviews were conducted to document the project’s needs. Phase I of the project focused on de-veloping a prototype for the application and phase II on developing the wrist-band. The team developed prototypes of a wristband that automatically applies vibration near the median nerve as the heart rate variability (HRV) deviates away from the normal threshold of the user, and an application that displays real-time heart rate variability signals as well as provides for relaxation. The development of the prototype is still in early progress. By creating this automated system, we aim to provide a solution to senior PD patients to relieve anxiety independently. .

关键词： vibration therapy Healthcare Application Parkinson’s Disease Anxiety Wristband Heart Rate Variability

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