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Acute Obstructive Hydrocephalus Caused by <i>Pseudomonas</i><i>aeruginosa</i>ventriculitis after Transsphenoidal Surgery: Case Report

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Open Journal of Modern Neurosurgery 2015年第1期5卷 1-5页

作者： Yasuhiko Hayashi Masayuki Iwato Daisuke Kita Katsuyoshi Miyashita Department of Neurosurgery Graduate School of Medical Science Kanazawa University Kanazawa Japan

Pseudomonas aeruginosa (P. aeruginosa) frequently causes various infections, some of which are serious and require prompt medical detection and appropriate antibiotic selection. Although P. aeruginosa commonly exists within the nasal cavity, meningitis or ventriculitis following transsphenoidal surgery to relieve P. aeruginosa has been reported only occasionally. However, as the endoscopic transnasal approach is more widely utilized for the suprasellar lesions, nosocomical P. aeruginosa infection associated with cerebrospinal fluid (CSF) leakage becomes more common in patients with panhypopituitarism who undergo transsphenoidal surgery. We report a case of a 36-year-old man with an intrasellar craniopharyngioma presenting with an acute obstructive hydrocephalus caused by P. aeruginosa ventriculitis following transsphenoidal surgery. Treatment with optimal antibiotics was initiated immediately after P. aeruginosa was recognized as the pathogen, and was continued for 3 months. After removal of the infected fascia and fat graft used for the closure of CSF leakage and sellar floor reconstruction, endoscopic third ventriculostomy was successfully performed to treat the obstructive hydrocephalus induced by the occlusion of the fourth ventricle outlet, resulting in a positive outcome. Although the obstructive hydrocephalus caused by P. aeruginosa is extremely rare, prompt detection and appropriate treatment should be required once P. aeruginosa ventriculitis happens.

关键词： Obstructive Hydrocephalus ventriculitis Pseudomonas aeruginosa Transsphenoidal Surgery

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Severe Infant Meningoencephalitis Caused by Salmonella Apeyeme: A Case Report

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Infectious Microbes & Diseases 2021年第4期3卷 214-217页

作者： Klaita Srisingh Sarunya Srijuntongsiri Yasinee Apiraknapanon Tanatporn Chuenkeson Raksit Chinnarakbumrung Chutima Phuaksaman Department of Pediatrics Faculty of MedicineNaresuan UniversityPhitsanulokThailand Department of Clinical Pathology Faculty of MedicineNaresuan UniversityPhitsanulokThailand Department of Pathology Faculty of MedicineNaresuan UniversityPhitsanulokThailand.

Salmonella enterica serovar Apeyeme is a rare pathogen that primarily affects ***,there are limited data about this infection in *** this case,a 7-month-old infant presented with high-grade fever without diarrhea for 12 hours prior to *** admission,he developed seizures and was referred for further *** was diagnosed with meningoencephalitis with complications of subdural effusion,empyema,and *** Apeyeme was found in cerebrospinal fluid culture,but no growth was detected in either blood or stool *** was given meropenem,vancomycin,and ciprofloxacin,but later developed disseminated intravascular *** clinical condition deteriorated over time,and he died 18 days after *** conclude,Salmonella Apeyeme infection should be considered if a patient is diagnosed with meningoencephalitis and has a history of poultry exposure.

关键词： meningoencephalitis nontyphoidal Salmonella Salmonella Apeyeme salmonellosis ventriculitis

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