检索结果-南通市图书馆

Activities of autonomic neurotransmitters in meibomian gland tissues are associated with menopausal dry eye

Neural Regeneration Research 2012年第35期7卷 2761-2769页

作者： Lianxiang Li Dongling Jin Jinsheng Gao Liguang Wang Xianjun Liu Jingzhang Wang Zhongxin Xu Department of Anatomy Histology and Embryology Laboratory of Basic Medicine Medical College Hebei University of Engineering Department of Pathology Medical College Hebei University of Engineering Department of Physiology Medical College Hebei University of Engineering Department of Biochemistry Medical College Hebei University of Engineering

The secretory activities of meibomian glands are regulated by the autonomic nervous system, The change in density and activity of autonomic nerves in meibomian glands during menopause play an important role in the pathogenesis of dry eye. In view of this, we established a dry eye rat model by removing the bilateral ovaries. We used neuropeptide Y and vasoactive intestinal polypeptide as markers of autonomic neurotransmitters. Our results showed that the concentration of estradiol in serum significantly decreased, the density of neuropeptide Y immunoreactivity in nerve fibers significantly increased, the density of vasoactive intestinal polypeptide immunoreactivity in nerve fibers significantly decreased, and the ratio of vasoactive intestinal polypeptide/neuropeptide Y positive staining significantly decreased. These results suggest that a decrease in ovary activity may lead to autonomic nervous system dysfunction, thereby affecting the secretory activity of the meibomian gland, which participates in sexual hormone imbalance-induced dry eye.

关键词： ovariectomy meibomian gland meibomian gland dysfunction neuropeptide Y vasoactive intestinalpolypeptide autonomic nervous system dysfunction dry eye sexual hormone rats autonomicnerve neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Watery diarrhea,hypokalemia and achlorhydria syndrome due to an adrenal pheochromocytoma

引用

World Journal of Gastroenterology 2007年第34期13卷 4649-4652页

作者： Shin-ichi Ikuta Chiaki Yasui Masahiro Kawanaka Tsukasa Aihara Hidenori Yoshie Hidenori Yanagi Masao Mitsunobu Ayako Sugihara Naoki Yamanaka Department of Surgery Meiwa General Hospital Hyogo 663-8186 Japan Department of Internal Medicine Meiwa General Hospital Hyogo 663-8186 Japan Department of Pathology Meiwa General Hospital Hyogo 663-8186 Japan

Watery diarrhea, hypokalemia and achlorhydria (WDHA) syndrome caused by vasoactive intestinal polypeptide (VIP) -producing tumor only rarely occurs in patients with nonpancreatic disease. A 49-year-old woman was referred for evaluation of a right adrenal tumor incidentally diagnosed by abdominal ultrasound during the investigation of chronic watery diarrhea. Laboratory findings showed hypokalemia and excessive production of VIP and catecholamines. After surgical resection of the tumor, diarrhea subsided and both electrolytes and affected hormone levels normalized. Immunohistochemical examination confirmed a diagnosis of pheochromocytoma, which contained VIP-positive ganglion-like cells. We herein present the clinical and histogenetic implications of this rare clinical entity, with literature review.

关键词： Pheochromocytoma vasoactive intestinalpolypeptide Watery diarrhea, hypokalemia andachlorhydria syndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：