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Impact of Early versus Late Amniotomy on Induction of Labor in Nulliparous Women after vaginally Administered misoprostol: A Randomized Clinical Trial

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Reproductive and Developmental Medicine 2021年第3期5卷 148-153页

作者： Mohamed Elsibai Anter Ayman Abd Elkader Shabbana Alaa Eldin Fatahlla Elhalaby Hager Abd Elshafy Abd Elfattah Youssif Nabih Ibrahim Elkhouly Department of Obstetrics and Gynecology Faculty of MedicineMenoufia UniversityMenoufiaEgypt

Objective::To investigate the effect of early versus late amniotomy after induction of labor(IOL)with vaginally administered ***::This randomized clinical trial was conducted at the Department of Obstetrics and Gynecology,Menoufia University,from May 2019 to March 2020,and included 120 nulliparous women at term(≥37 weeks’gestation)undergoing ***-generated randomization was used to randomize the participants into either the early amniotomy group(3 cm cervical dilatation;n=60)or the late amniotomy group(7 cm cervical dilatation;n=60).All participants received misoprostol(25μg)vaginally to induce *** primary outcome was the induction-to-delivery interval,defined as the time from the initiation of IOL to the time of ***::Women in the early amniotomy group had a shorter duration of labor(12.60±5.36 h)than those in the late amniotomy group(16.67±7.26 h).The mean time from rupture of the fetal membrane to delivery was significantly shorter in the late(2.51±0.36 h)than in the early amniotomy group(3.1±0.89 h).There was no statistically significant difference between the groups in terms of maternal complications(fever,nausea,vomiting,and uterine hyperstimulation)or neonatal complications(meconium-stained liquor,APGAR scorevaginally administered misoprostol followed by early amniotomy was accompanied by a shorter duration of labor and decreased use of *** was no significant difference between the early and late amniotomy groups in terms of the rate of cesarean section or maternal and neonatal complications.

关键词： Amniotomy Induction of Labor Neonatal Outcomes vaginal misoprostol

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