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Prevention and Treatment of vaginal bleeding after Drug-induced Abortion by Yaoliuan Capsule and Its Effects on Menses Recovery

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2005年第3期25卷 346-347,367页

作者：金志春黄光英 Institute of Integrated Traditional Chinese and Western Medicine Tongij Hospital Tongji Medical CollegeHuazhong University Science and Technology

In order to explore the effect of Yaoliuan capsule in the prevention and treatment of vaginal bleeding after drug-induced abortion and menses recovery after drug-induced abortion, 323 cases of gestation period ≤ 49 days and without contraindication, were divided randomly into study group (168 cases, taking Yaoliuan capsule) and control group (155 cases, taking placebo capsule). The results showed that in the study group, there were 161 cases (95.8 %) of complete abortion, 7 cases (4.2 %) of incomplete abortion; In the control group, there were 146 cases (94.2 %) of complete abortion, 6 cases (3.9 %) of incomplete abortion, 3 cases (1.9 %) of abortion failure. The vaginal bleeding time was 5-25 days (mean 10.8 days) in study group, while that was 6-62 days (mean 19.1 days) in control group. The menstrual cycle was 30.5±5.2 days and 33.8 d±8.6 days respectively in study and control groups. The menstrual period was 6.1±3.5 days and 9.9±5.1 days respectively in study and control groups. Yaoliuan capsule is an effective drug to prevent and treat vaginal bleeding following drug-induced abortion, promote menstruation recovery and prevent pelvic infection.

关键词： Yaoliuan capsule mifepristone misoprostol vaginal bleeding

Clinical Study on Prevention and Treatment of vaginal bleeding with Yaoliuan Capsule (药流安胶囊) after Drug-Induced Abortion

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Chinese Journal of Integrative Medicine 2000年第2期6卷 137-138页

作者：金志春张敦兰

vaginal Cellular Angiofibroma with Heavy bleeding: A Case Report

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Open Journal of Obstetrics and Gynecology 2020年第11期10卷 1609-1615页

作者： Anh Q. Nguyen Cassandra L. Presti Graham Nelsen Francine McLeod Department of Obstetrics and Gynecology Inova Fairfax Hospital Falls Church VA USA Department Obstetrics and Gynecology School of Medicine University of Virginia Inova Campus Falls Church VA USA

Cellular angiofibroma is a rare mesenchymal tumor that most commonly presents as an asymptomatic well-circumscribed mass in the vulva. Very few cases have been found in the vagina and even fewer presented with vaginal bleeding. A 54-year-old female presented to the emergency department with five months of vaginal bleeding and symptomatic anemia requiring blood transfusion. Upon physical examination, she was found to have a firm 4 cm posterior vaginal mass, distinctly distal to the cervix. The mass was resected and diagnosed as a vaginal cellular angiofibroma on pathologic evaluation. The patient did well post-operatively with recommended follow-up every six months. The common differential diagnosis for a bleeding vaginal mass includes leiomyoma, angiofibroblastoma, aggressive angiomyxoma, squamous cell carcinoma, and adenocarcinoma. In this case, cellular angiofibroma presented as a vaginal mass with heavy bleeding leading to severe anemia. Early involvement of gynecologic oncology can help to optimize patients’ evaluation and management.

关键词： vaginal Cellular Angiofibroma vaginal Tumor vaginal bleeding

Efficacy and safety of Cimicifuga foetida extract on menopausal syndrome in Chinese women

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Chinese Medical Journal 2013年第11期126卷 2034-2038页

作者： ZHENG Ting-ping SUN Ai-jun XUE Wei WANG Ya-ping JIANG Ying ZHANG Ying LANG Jing-he Department of Obstetrics and Gynecology Peking Union MedicalCollege Hospital Chinese Academy of Medical Sciences & PekingUnion Medical College Beijing 100730 China

Background It is now recognized that Cimicifuga foetida extract is effective in alleviating menopausal symptoms. But the durations reported were usually short. This paper compares the clinical effects of different regimens of three-month course on climacteric symptoms in Chinese women, so as to evaluate the efficacy and safety of Cimicifuga foefida extract. Methods This was a prospective, randomized trial. Ninety-six early menopausal women were recruited and randomly assigned into 3 groups to take different kinds of medicine for 3 months; participants were given Cimicifuga foefida extract daily in group A （n=32）, given estradiol valerate and progesterone capsule cycle sequentially in group B （n=32）, and given estradiol valerate and medroxyprogesterone acetate cycle sequentially in group C （n=32）. The questionnaires of Kupperman menopause index, Menopause-Specific Quality of Life, and Hospital Anxiety and Depression Scale were finished before and after the treatment. The status of vaginal bleeding and breast tenderness was recorded every day. Results Eighty-nine participants （89/96, 92.7%） completed the treatment. Kupperman menopause index decreased after taking the medicine for 3 months in each group （with all P〈0.001）, but the score after the treatment was higher in group A than in the other 2 groups. Except for the score of sexual domain in group A （P=0.103）, the scores of all domains of the Menopause-Specific Quality of Life decreased significantly after the treatment in all groups （with all P〈-0.01）. Score of anxity decreased significantly in group A （P=0.0l 5） and B （P=0.003）. Incidence of breast tenderness was 12.9% （4/31） in groupA, 36.7% （11/30） in group B, and 14.3% （4/28） in group C. Incidence of vaginal bleeding was 6.5% （2/31）in group A, 26.7% （8/30） in group B, and 82.1% （23/28）in group C. Conclusions Cimicifuga foeticla extract is effective and safe in the treatment of menopausal syndrome. It is worth extending its use in the treatment of climacteric c

关键词： Cimicifuga foetida extract menopause Kupperman menopause index menopause-specific quality of life vaginal bleeding breast tenderness

Special epithelioid trophoblastic tumor:A case report

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World Journal of Clinical Cases 2022年第26期10卷 9354-9360页

作者： Ya-Nan Wang Yan Dong Lin Wang Ya-Hui Chen Hai-Yang Hu Jing Guo Lin Sun Departments of Clinical Jining Medical UniversityJining 272000Shandong ProvinceChina Department of Gynecology Affiliated Hospital of Jining Medical UniversityJining 272000Shandong ProvinceChina Department of Pathology Affiliated Hospital of Jining Medical UniversityJining 272000Shandong ProvinceChina

BACKGROUND Epithelioid trophoblastic tumor(ETT)is a special type of gestational trophoblastic ***,its pathogenesis has been incompletely *** rarely occurs in the ovaries and fallopian tubes,unlike placental site trophoblastic tumor,requiring a histopathological biopsy and immunohistochemistry for further *** SUMMARY A 29-year-old woman with irregular vaginal bleeding and elevated serum chorionic gonadotropin(β-hCG)levels presented similar symptoms to ectopic *** ultrasound revealed abnormal echoes of the left ***,the pathology of the left ovary and fallopian tube was reported as *** patient was followed up with regular hCG measurements and *** blood hCG values showed an upward trend 3 mo after the operation and then chemotherapy was *** current health status is *** For women of childbearing age with elevated serumβ-hCG levels,practitioners should consider ETT and be alert to the poor prognosis of the *** surgery,the patient’s condition should be closely observed to prevent recurrence and *** chemotherapy is only helpful for treating the disease to a certain extent.

关键词： Trophoblastic tumor Epithelioid trophoblastic tumor Serum chorionic gonadotropin vaginal bleeding The partial hydatidiform mole Choriocarcinoma Case report

Cervical Metastasis from Renal Cell Carcinoma

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Chinese Medical Journal 2016年第8期129卷 1005-1006页

作者： Wen-Xiang Wang Wen-Jing Zhang Kai-Xuan Yang Xiao Tang Zhi-Lan Peng Department of Gynecology and Obstetrics West China Second University Hospital Sichuan University Chengdu Sichuan 610001 China Department of Gynecology Oncology The Central Hospital of Xinxiang Xinxiang Henan 453000 China Department of Pathology West China Second University Hospital Sichuan University Chengdu Sichuan 610001 China

To the Editor：A 43-year-old woman,having a renal cell carcinoma （RCC） treated with radical nephrectomy 15 months ago in West China Hospital,was consulted to our gynecology outpatient clinic for a 3-month history of vaginal bleeding in March *** the clinic,blood transfusion was given to the patient at a local hospital due to heavy vaginal bleeding.

关键词： Cervical Metastasis Renal Cell Carcinoma vaginal bleeding

Nail penetrating trauma： a rare cause of vesicovaginal fistula

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Chinese Journal of Traumatology 2014年第6期17卷 351-353页

作者： Mohammad Asl Zare Ali Kamalati Saeed Esmailnia Department of Urology Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran Department of Urology Faculty of Medicine Kerman University of Medical Sciences Kerman Iran

Vesicovaginal fistula （VVF） may be caused by prolonged obstructed labor, gynecologic, urologic, or other pelvic surgery, malignancy, radiation, infection and trauma. Here we report a case of VVF caused by nail penetrating trauma in a young woman with genital bleeding after first intercourse. This is a rare etiology of VVF. We also explain the operative technique used to repair the fistula.

关键词： vaginal bleeding Wounds, penetrating Vesicovaginal fistula

Late Αntepartum Ηemorrhage and Neonatal Outcome: A Retrospective Study

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Open Journal of Obstetrics and Gynecology 2016年第2期6卷 107-116页

作者： Panagiotis Tsikouras Zacharoula Koukouli Anastasios Liberis Bachar Manav Constantinos Bouschanetzis Panagiotis Naoumis Marina Dimitraki Georgios Galazios Department of Obstetrics and Gynecology Democritus University of Thrace Alexandroupoli Greece

To retrospectively evaluate the causes, the management and neonatal outcome in pregnancies complicated with late antepartum hemorrhage (APH), defined as vaginal bleeding during the third trimester of pregnancy. Methods: We retrospectively identified all eligible patients at a single institution from January 1990 to December 2012. A thorough research was made through patients’ medical and obstetrical records. The various causes of late APH were compared to each other regarding the parameters of the neonatal outcome. Multiple regression models were applied for gestational age (GA) at birth, birth weight, Apgar score at first and fifth minute and selection of modus of delivery. Results: 480 patients were included in the study, in a total of 7221 pregnancies. The causes of APH were: cervical dilatation (n = 54, 11.3%), central placental abruption (n = 57, 11.9%), peripheral placental abruption (n = 59, 12.3%), placenta previa (n = 140, 29.2%), others non-related to pregnancy (n = 42, 8.8%), uterine rupture (n = 2, 0.4%) and unknown etiology (n = 126, 26.3%). Overall, 253 neonates (52.7%) were born prematurely at gestational age below 37th week. 37 pregnancies (7.7%) resulted in giving birth prior to 32 weeks of gestation. In multivariable analysis, the cause of hemorrhage was found to be an important independent predictive factor for gestational age (GA) at birth, birth weight, Apgar scores at first and fifth minute and modus of delivery. Preeclampsia, diabetes, thyroid disorder and smoking were associated with decrease of GA at birth. Birth weight below 1500 gr and GA at birth was found to be significant independent factors for Apgar score at first and fifth minute respectively. Modus of delivery did not significantly alter Apgar score. Conclusions: Late APH required immediate evaluation of the general condition of the pregnant woman and the fetus. The cause of APH was important in the prognosis of the neonatal outcome. As long as maternal and fetal status were ensured

关键词： APH vaginal bleeding Neonatal Outcome Prognostic Factors

Uterine Arteriovenous Malformation Acquired after Cesarean Section: A Case Report

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Open Journal of Obstetrics and Gynecology 2021年第11期11卷 1512-1516页

作者： Ana Lúcia Isotton Leandro Armani Scaffaro Ellen Machado Arlindo Anne Bergmann Nicolas Karpouzas Vicentini Janete Vettorazzi Service of Obstetrics and Gynecology and Interventional Radiology Department Hospital Moinhos de Vento Porto Alegre Por-to Alegre/RS Brazil Medicina Fetal Porto Alegre Porto Alegre/RS Brazil Post Graduation Program in Health Sciences: Gynecology and Obstetrics Faculdade de Medicina da Universidade Federal do Rio Grande do Sul (UFRGS) RS Brazil

Background: Uterine arteriovenous malformation (AVM) is a rare, potentially life-threatening cause of abnormal uterine bleeding that can be acquired following a cesarean section. The diagnosis is difficult, often misdiagnosed with retained products of conception and placenta accreta. Transarterial embolization (TAE) is an efficacious and effective method of treating AVM, particularly in patients of reproductive age. Case Report: A 41-year-old, nulliparous woman, started with a history of abnormal uterine bleeding 30 days after a cesarean section. She didn’t have anaemia and beta-human chorionic gonadotropin (beta-hCG) was negative. The transvaginal color Doppler ultrasound showed multiple vascular channels within myometrium showing colored mosaic patterns suggesting AVM, confirmed by Magnetic Resonance Imaging. The patient was referred to perform a Computed Tomography Angiography and right uterine artery embolization without any vascular complications. Conclusion: AVM is a rare consequence of cesarean section but has to be considered in cases of persistent uterine bleeding in the puerperium. Embolization is a sa

关键词： Arteriovenous Malformation Embolization Therapeutic vaginal bleeding Cesarean Section