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Global Rates and Prevalence of Urogenital Mycoplasmosis: Assembly of a Dataset from Peer-Reviewed Literature

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Open Journal of Medical Microbiology 2013年第2期3卷 105-124页

作者： Jennifer A. Jones Nufar Chaban Meghan May Department of Biological Sciences Fisher College of Science and Mathematics Towson University Towson USA

Rates of Urogenital mycoplasmosis associated with Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum have been reported numerous times, and frequently show a wide range of findings. Differing diagnostic techniques, population targeting, temporal and spatial data collection, and coincident infections make the conclusions from these analyses difficult to compare. We generated a single data set including the infection rate, geographic location, year, study population, diagnostic method, and clinical signs for these organisms by performing literature searches with the species names and compiling the findings. Studies focusing on basic research or reporting clinical surveys where these criteria were not reported were excluded. A statistical analysis of the dataset parameters found that: diagnostic method does not significantly correlate with positive specimen rate but does correlate with the year of publication, and the number of publications correlated significantly with year, indicating that this topic is of growing interest. Further analysis indicated that Ureaplasma species infection rate is significantly higher in pregnant women across all studies. Associations with distinct clinical presentation could not be made on datasets assembled across studies due to the number of confounding variables presented in each. The generated data set represents a large amount of temporal, geographic, and clinical data that can be utilized in future communications.

关键词： Mycoplasma genitalium Mycoplasma hominis Ureaplasma Urogenital Mycoplasma

A Clinical Research about the Intermittent Medication Treatment on the Female Urogenital Tract Mycoplasma Infection

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Open Journal of Obstetrics and Gynecology 2014年第13期4卷 800-804页

作者： Guosheng Su Xiaolu Luo Rongwei Liang Lianhua Pan The Fourth People’s Hospital Nanning China Maternal and Child Health Care Hospital Qinzhou China

Object: To explore a better treatment on the female Urogenital tract mycoplasma infection so as to ensure the health of female reproduction. Method: 115 female patients with Urogenital tract?mycoplasma infection?are selected, including 63 patients acted as a group for intermittent medication treatment;that is to say, the ones that are confirmed to be sensitive drugs to those 63 patients are chosen, and let them take this medication for 15 days and stop taking it for 7 days and after that continue to take it for 10 days. The other 52 patients in the other group which acts as a contrast to the former group are cured with a course of conventional treatment for 15 - 21 days. Results: As to those 115 female patients with Urogenital tract mycoplasma infection, 43 patients get relapsed, and 27 patients of them are in the contrast group and 16 patients are in the treatment group.?There is obvious difference on the contrast of relapse rate between the treatment group and contrast group, and they are P Urogenital tract mycoplasma infection are cured with a traditional treatment, because of the side effects of drugs, they are not likely to take medicines that are required to making the cure rate become lower and the relapse rate become higher. But intermittent medication is designed with the half-life period of medicine, which makes the medicine can be digested and absorbed easily, and the cure rate is high and the relapse rate is low. With this research we found a more effective method of the treatment on the female Urogenital tract mycoplasma infection and showed the clinical significance in intermittent medication.

关键词： Intermittent Urogenital Tract Mycoplasma Drug Sensitivity

A Novel Technique for Removal of Urogenital Magnetic Foreign Bodies

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Open Journal of Urology 2018年第8期8卷 223-227页

作者： Kenneth R. Hassler Kaveh Homayoon Department of Surgery Maricopa Integrated Health System Phoenix USA Department of Surgery—Urology Division Maricopa Integrated Health System Phoenix USA

Background: There were 800 individual case reports of Urogenital foreign bodies in the English literature from 1755 to 1999. The use of Urogenital foreign bodies for sexual pleasure is a common occurrence in today’s population. The aim of this discussion is the management of scrotal injury caused by magnetic Urogenital foreign bodies. Case Presentation: 56-year-old male with scrotal tissue entrapped between two opposed magnet rings. Self-reported attempts at removal were unsuccessful and caused for presentation to the emergency department. Additional attempts at removal by medical staff unsuccessful in emergency department and therefore the patient proceeded to the operating room. Intraoperatively the use of two cardiac magnets allowed for removal without a need for invasive surgical procedure. Conclusion: Cardiac magnets are preferred means of removal for entrapped skin between magnetic foreign bodies that could be utilized at the bedside.

关键词： Urogenital Foreign Body Magnet Magnetic Scrotal Scrotum Urogenital Magnetic Foreign Body Scrotal Magnets Magnetic Foreign Body Urogenital Magnet Removal Scrotal Magnet Removal

Vidas CHL Assay in the Detection of Urogenital Chlamydia Trachomatis Infection

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Chinese Journal of Sexually Transmitted Infections 2002年第2期2卷 32-36页

作者：黄澍杰程文海吴志周柯建良黄东辉谢礼豪谭仲楷 Jiangmen Hospital for Skin Disease and STDs 62 Yuejin Rd Jiangmen Hospital for Skin Disease and STDs 62 Yuejin Rd Jiangmen 529000 Guang Dong Province China.MD

Objectives: To evaluate the Vidas Chlamydia (CHL) assayfor detecting C.Trachomatis with swabs and first catch urine(FCU) specimens from STD patients and high riskpopulations. Methods: A total of 383 pahents were tested with tissueculture (TC), Vidas CHL and polymerase chain reaction (PCR)for C.trachomatis on male and female swabs, with Vidas CHLtesting male FCU specimens. CHL positive and equivocalresults were confirmed with a blocking assay (CHB). Truepositive were defined as either TC positive, or TC negtive butCHL and PCR positive. The performance of TC, CHL andPCR were evaluated according to this expanded goldstandard. Results: Compared with the expanded gold standard, 54 ofthe 232 male specimens were true positive results. For maleswabs, TC, CHL and PCR had sensitivities of 90.7%, 96.3%and 94.4%, and specificities of 100%, 98.3% and 97.2%,respectively. Differences were not statistically significant. Formale FCU specimens, CHL sensitivity and specificity were83.3% and 98.3%; there was little difference between theseresults and that of matched swabs. Compared with theexpanded gold standard, 28 of the 151 female swabs were truepositive; TC, CHL and PCR had sensitivities of 82.1%, 100%and 96.4%, and specificities of 100%, 98.4% and 97.6%,respectively. The difference was also not significant. Conclusions: Vidas CHL assay is very scnsitive and specificfor C.trachomatis detection with swab specimens of male andfemale STD patients. For male FCU specimens, the assay alsohad high sensitivity and specificity. CHB may not be needed inthe routine detection or Chlamydia infections. Populationswith higher incidence of C.trachomatis infection.

关键词： Chlamydia trachomatis Vidas Chlamydia Urogenital System Assay

Expression of the Gene Encoding Secretor Type Galactoside 2 α Fucosyltransferase (FUT2) and CD44 Marker in Urogenital Tumors

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Open Journal of Genetics 2016年第4期6卷 96-104页

作者： M. A. Ensinck N. Lebensohn S. García Borrás L. Racca C. Cotorruelo C. Biondi Area Immunology Department of Clinical Biochemistry National University of Rosario Rosario Argentina

The aim of this work was to investigate the FUT2 gene, the secretor status and the expression of CD44 protein in epithelial cells obtain from saliva and urine samples from patients with Urogenital tumours. We studied 104 subjects. Half of them had Urogenital tumours, while the other half was the healthy control group. We determined the secretor status in saliva with the haemagglutination inhibition technique. We analyzed the FUT2 polymorphism by allele specific oligonucleotide–polymerase chain reaction (ASO-PCR) with specific primers for the G428 allele and the wild type allele of FUT2 gene. We found higher intensity of Urogenital disease in the non-secretor group (OR = 3.44). In contrast with the healthy population, 51.6% of the patients with potential malignant Urogenital lesions and cancerous lesions were non-secretors. We also investigate by confocal microscopy, the expression of CD44 protein in epithelial cells obtained from urine samples from these patients. The results obtained also showed fluorescence corresponding to the presence of CD44 protein in samples from patients diagnosed with cancer. Our study suggests that the lack of wild type FUT2 gene and a nonsecretor status appear to be an associated risk marker for the development of Urogenital tumors. Several mechanisms, based on the properties of CD44 as the major hyaluronan CD44 in cell carcinomas receptor, have been proposed to explain the role of elevated CD44 expression during tumour development and progression. CD44 might be a good candidate as a predictor of prognosis in this group of cancers.

关键词： FUT2 Secretor Status Tumours Urogenital

Urogenital Fistula in Cote d’Ivoire: Epidemiological, Clinical and Therapeutical Aspects

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Open Journal of Urology 2017年第11期7卷 187-195页

作者： B. Kouame F. Kramo F. M. Gbeli A. Fofana A. G. Kakou J. J. Gandonou J. J. Damba M. Roua S. Yassin P. G. Konan A. H. Dekou G. A. Ouegnin K. Manzan Urology Department UHC of Cocody Abidjan Cote d’Ivoire

Goal: Contribute to improve treatment of patients suffering from Urogenital fistula (UGF). Materials and methods: It was a descriptive and prospective study conducted by the United Nations Population Fund (UNFPA) and the Ivorian government, on treatment of fistulas. The caravan took place on 4 periods of 10 days each and has enabled us to recruit 95 patients in the gynecological emergency department of Bouake’s University Hospital Center (UHC) and from the surgical emergencies departments of the regional hospital centers (RHC) of Man and Bondoukou, in Man from 14th to 23rd of August 2013, then from 24th March to 02nd of April 2014;in Bouaké from 06th to 15th of November 2013 and in Bondoukou from 13th to 22nd of December 2013, respectively. Results: Average age of patients was of 30.8 years. 50 patients were single (52.6%). 44.2% of patients were farmers. In 95.8% of cases it was about obstetrical fistulas of which 52.6% were caused by caesareans. Average duration of delivery labor was of 2.3 days. Vesicovaginal fistulas represented 65.3% of UGF. Suture split were carried out on 90 patients (94.7%). Within 01 month, success rate was of 63.9% for 83 known patients. Conclusion: Incidence of UGF in our country is certainly underestimated. They are mainly of obstetrical origin and treatment relies on sutures split which give satisfactory results.

关键词： Urogenital Fistula Suture Split

Results of the Management of Urogenital Fistulae from Community Caravans

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Open Journal of Obstetrics and Gynecology 2017年第8期7卷 858-865页

作者： Eric Bohoussou Jean Marc Dia Gerard Okon Lydie Djanhan Bilé Kouamé Yao Djanhan Gabriel Gnanazan Serges Boni Department of Gynecology and Obstetrics University and Hospital Center of Treichville (CHUT) Abidjan Cote d’Ivoire National Coordinator Fistula Project UNFPA Abidjan Cote d’Ivoire Department of Gynecology and Obstetrics University and Hospital Center of Bouaké (CHUB) Bouaké Cote d’Ivoire Department of Urology University and Hospital Center of Treichville (CHUT) Abidjan Cote d’Ivoire Department of Gynecology and Obstetrics University and Hospital Center of Cocody (CHUC) Abidjan Cote d’Ivoire

Objective: To report the experience of surgical caravans for Urogenital fistulas care. Methodology: This was a retrospective study covering the period from January 2014 to December 2014 and which took place on 7 sites of fistula care. The epidemiological, anatomoclinical, therapeutic and evolutionary aspects were studied. Results: 346 patients were operated during 14 caravans. Their average age was 33.11 years (range: 12 to 70 years). Most of these patients were without remunerative activities (80%) and without education (63.3%). The average duration of fistula progression was 6.08 years (range: 0 to 42 years). Obstetrical etiology was predominant (87.9%). According to the classification of Kees Waaldijk, fistulas were divided into type I (67.4%), type II (21.1%), and type III (11.5%). The most common surgical approach was the transvaginal route (82.1%). The vesicovaginal splitting with separated suture of the bladder and the vagina was the basic technique (94.7%). The therapeutic results were judged after a follow-up of 1 month and 3 months. Across the cohort, 80 patients (23.1%) were lost of sight for follow-up at 1 month and 245 (70%) at 3 months. The success rates evaluated in patients reviewed at 1 month and 3 months were respectively 70% and 64%. Conclusion: The incidence of Urogenital fistulas is still high in Cote d'Ivoire. Various anatomoclinical varieties have been identified and treated with satisfactory results in poorly equipped local structures.

关键词： Urogenital Fistulas Epidemiology Diagnosis Treatment

THE RELATION OF UREAPLASMA UREALYTICUM INFECTION TO Urogenital STONE FORMATION

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Medical Bulletin of Shanghai Jiaotong University 1999年第2期20卷 71-75页

作者：徐晨王一飞张惠心

Objective To study the mechanism of Ureaplasma urealyticum (UU) infection to the genesis of Urogenital stone. Methods One hundred male SD rats were randomly divided into 3 groups: group A (n=45) rats were inoculated intravesically with 1ml (105 CCU/ml) of UU serotype 8 (T960) broth. Group B (n=22) rats were treated as the group A, 3 months later, administration of Minomycin (20~100mg/kg, oral daily for 14d) was given to each rat. Group C (n=33) rats were given sterile broth intravesically as control. After UU inoculation UU were collected from different parts of Urogenital tract and cultured. In 3 testes positive in UU culture, UU specilic DNA fragments were tested by PCR technique. Results The percentages of positive UU culture in groop A animals were 87.5% in urinary bladders, 62.5% in testes, 55% in ePididymides, 65% in seminal vesicles, and 57.5% in prostates. The corresponding percentages in group B were significantly lower than that in group A (P0.05). The main comPonent of stone was struvite (MgNH4PO4 6H2O). MicroscOPically, microlithes were found in seminderous tubules in 4 infected rats. In microlithes containing tubules, germinal cells and Sertoli cells were exfoliated or even absent. In some tubules, only membrana limitans remained intact. No microlithes found in testicular interstitial tissue. Cooclusion UU infection does induce Urogenital stones and Minomycin can inhibit UU growth. With interlerence on spermatogenesis, UU may be one of the causes of male inlertility.

关键词： Ureaplasma urealyticum PCR urease Urogenital stone infertility

Neonatal Infection among Women with Prior Premature Labor

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Open Journal of Obstetrics and Gynecology 2015年第15期5卷 833-838页

作者： Tandu-Umba Barthélémy Kalonji Tshianyi David Department of Obstetrics and Gynecology University Clinics Kinshasa DR Congo

Objectives: Since studies demonstrate that neonates born to mothers having been cared for premature labor will suffer from congenital neonatal sepsis, we aimed to evaluate the prevalence and main risk factors of neonatal infection among mothers having experienced a prior premature labor. Methods: This was a cross sectional study carried out from January 1st throughout 31st December, 2013 at the university clinics of Kinshasa. It concerned all delivered women at term having been cared for premature labor prior to giving birth a live newborn. Maternal variables of interest were: parity, gestation, age, intrapartum fever, malaria, Urogenital infection during the last 2 weeks before delivery (UGI), premature rupture of membranes (PROM), cervical cerclage, meconium-stained amniotic fluid (MSAF) and the way of delivery. For neonates attention was paid on gestational age, birth weight, admission at neonatal intensive care unit (ANICU) and infection as stated within three days after birth. T-test and Chi-square were used where appropriate. Logistic analysis was used to determine the risk for maternal variables to induce neonatal infection (OR and CI), the significance stated at p < 0.05. Results: Fifty two mother-infant couples were recruited. Of these 19 neonates were infected (prevalence of 36.5%). Mean age, gestational age and birth weight were 30.19 ± 5.32 years, 37.2 ± 2 weeks and 2638 ± 588 g, respectively. Infected neonates had their gestational age and birth weight significantly lower whilst proportion of ANICU higher than that on non infected. Prematurity, PROM, UGI, prior cerclage and MSAF were significantly more frequent in couples with neonatal infection. Prematurity, birth weight <2500 g and UGI were found to enhance the risk by 3 to 4 times. Conclusion: The prevalence of neonatal infection was very high. Prematurity, birth weight <2500 g and maternal UGI were found to enhance the risk by 3 to 4 times.

关键词： Prior Premature Labor Maternal Urogenital Infection Neonatal Infection Risk Factors