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Correlation between glycated hemoglobin A1c,urinary microalbumin,urinary creatinine,β2 microglobulin,retinol binding protein and diabetic retinopathy

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World Journal of Diabetes 2023年第7期14卷 1103-1111页

作者： Jia-Jia Song Xiao-Fang Han Jian-Feng Chen Ke-Mei Liu Department of Endocrinology The Second People’s Hospital of HefeiHefei Hospital Affiliated to Anhui Medical UniversityHefei 230011Anhui ProvinceChina

BACKGROUND Retinopathy is the most common microvascular disease of type 2 diabetes,and seriously threatens the life,health and quality of life of *** is worth noting that the development of diabetic retinopathy(DR)can be hidden,with few ***,the preliminary screening of diabetic patients should identify DR as soon as possible,delay disease progression,and play a vital role in its diagnosis and *** To investigate the correlation between glycated hemoglobin A1c(HbA1c),urinary microalbumin(U-mALB),urinary creatinine(U-CR),mALB/U-CR ratio,β2 microglobulin(β2MG),retinol binding protein(RBP)and *** A total of 180 patients with type 2 diabetes mellitus attending the Second People’s Hospital of Hefei from January 2022 to August 2022 were retrospectively enrolled by *** on whether they had combined retinopathy and its degree,68 patients with diabetes mellitus without retinopathy(NDR)were assigned to the NDR group,54 patients with non-proliferative DR(NPDR)to the NPDR group,and 58 patients with proliferative DR to the PDR *** data,and HbA1c,mALB,β2MG,RBP,mALB/U-CR and U-CR results were collected from the patients and compared among the ***'s correlation method was used to analyze the correlation between HbA1c,mALB,β2MG,RBP,mALB/U-CR and U-CR indices,and multiple linear regression was applied to identify the risk factors for *** operator characteristic(ROC)curves were also *** The differences in age,gender,systolic and diastolic blood pressure between the groups were not statistically significantly(P>0.05),but the difference in disease duration was statistically significant(P0.05).HbA1c in the PDR group was higher than that in the NPDR and NDR groups(P<0.05).The levels of m

关键词： Diabetic retinopathy β2 microglobulin Retinol-binding protein urinary microalbumin urinary creatinine

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Estimation of urinary iodine excretion by iodine/creatinine ratio from morning spot urine in school-age children

Estimation of urinary iodine excretion by iodine/creatinine ...

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第七届全国中西医结合营养学术会议

作者： Wanqi Zhang Wen Chen Xiaohui Guo Jun Shen Long Tan Laixiang Lin Yan Ye Yalan Wu Wei Wang Wenqiang Wang Wen Jiang Jianchao Bian Department of Nutrition and Food Hygiene School of Public HealthTianjin Medical University Department of Sanitary Chemistry School of Public HealthTianjin Medical University Tianjin Institution of Endocrinology Tianjin Medical University Shandong Institute for Endemic Disease Control and Research

Objective:To evaluate the validity of iodine/creatinine ratio(UI/Cr)from spot urines in estimating24-h urinary iodine excretion(24-h UIE)in school-age ***:A cross-sectional *** repeated collections of 24-h urine and morning spot urine samples were obtained within one month.24-h urinary iodine concentration(24-h UIC),24-h urinary creatinine concentration(24-h U-Cr),24-h urinary volume(24-h U-vol),morning spot urinary iodine concentration(MUIC)and morning spot urinary creatinine concentration(MU-Cr)were measured in all *** 24-h UIE was calculated by 24-h UIC multiplying 24-h U-vol,while estimated 24-h UIE was calculated by morning spot urinary iodine/creatinine ratio(MUI/Cr)multiplying 24-h urinary creatinine excretion(24-h UCrE).Setting:Ningjin and Lingxian Counties,Shandong,***:981 healthy school-age children Results:No significant differences were observed in MUI/Cr,24-h UIC and measured 24-h UIE between twice repeated ***/Cr,24-h UI/Cr and estimated 24-h UIE were strongly correlated with measured 24-h *** Kappa value a was 0.615 in first collection and 0.599 in second one,demonstrating a good agreement between estimated and measured 24-h *** 24-h UIE was slightly lower than measured 24-h UIE in both *** 24-h UIE and estimated 24-h UIE were significantly correlated with ***,no differences were observed in MUI/Cr and 24-h UI/Cr among different ***:Estimated 24-h UIE from morning spot urine could be a valid and reliable alternative for measured 24-h UIE from 24-h urine sample in evaluating individual iodine intake,even though there was 10%4%underestimation.

关键词： 24-h urine urinary iodine urinary creatinine iodine/creatinine ratio children

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