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primary ascending colon cancer accompanying skip metastases in left shoulder skin and left neck lymph node: A case report

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World Journal of Clinical Cases 2022年第23期10卷 8262-8270页

作者： Jun-Chao Zhou Jian-Jun Wang Tao Liu Qin Tong Yue-Jun Fang Zhang-Qiang Wu Qiang Hong Graduate School Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Surgical Oncology Jinhua Guangfu Oncology HospitalJinhua 321000Zhejiang ProvinceChina Department of General Surgery The Fourth Affiliated Hospital Zhejiang University School of MedicineJinhua 322000Zhejiang ProvinceChina

BACKGROUND Lymph node skip metastases are common in lung,breast,and thyroid cancer patients,but are rare in colon cancer ***,lymph node skip metastases occur in 1%-3%of colon cancer *** reports have demonstrated colon cancer skip metastases involving the retropancreatic and portocaval lymph nodes and Virchow's node;however,reports involving skip metastases into the left neck lymph nodes and left shoulder skin are extremely rare,as are related reports of clinical treatment and *** SUMMARY A 44-year-old Chinese man was admitted to the hospital for evaluation of persistent shoulder pain for 3 d and a cutaneous mass(3.0 cm×2.0 cm)on the left *** left shoulder cutaneous mass was excised and bisected,revealing tissues with a fish-like *** pathologic diagnosis of the cutaneous mass suggested a signature[CDX-2(++),CK20(++),Ki-67(+)>50%]of infiltrating or metastatic colorectal *** enhanced computed tomography scan of the abdomen revealed chronic appendicitis with fecal stone formation,cecal edema,and a pelvic effusion.A colonoscopy revealed a cauliflower-like mass within the ascending colon area that involved the *** surface of the ascending colon mass was eroded and bleeding;a biopsy was *** pathologic diagnosis of the colonoscopy biopsy was an ascending colon mucinous *** patient underwent a laparoscopic radical resection of the right colon based on the pathological *** tumor was 5.0 cm×4.5 cm×1.8 cm in size and infiltrated the entire thickness of the intestinal wall with vascular tumor *** nerve tissue involvement was *** ileum and colon resection margins were *** postoperative pathologic analysis revealed non-metastatic involvement of ileocecal,pericolic,or peri-ileal lymph *** postoperative medical examination revealed palpably enlarged lymph nodes in the left neck,and the following color Doppler ultrasound examination of the

关键词： Colon cancer Skip metastasis Skin metastasis unknown primary tumor Case report

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Malignant Peripheral Nerve Sheath tumor of the Thigh Invading the Superficial Femoral Artery, with Necrotic Lung Metastases as Presenting Symptoms

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Advances in Lung Cancer 2020年第2期9卷 24-29页

作者： Patrick Mailleux François Buche Geoffrey Colin Department of Imaging Clinique Bouge Bouge Belgium Department of Vascular Surgery Clinique St Luc Bouge Belgium

A NF1 (neurofibromatosis 1) patient developed multiple necrotic lung metastases from a sciatic malignant peripheral nerve sheath tumor (MPNST) invading the superficial femoral artery. The first diagnosis was metastases of a non-small-cell adenocarcinoma because the right calf MPNST was not clinically noticeable ant that the chest/abdomen PET/CT did not include the region of the legs. When the MPNST was diagnosed, new histological analysis on the metastases changed the diagnosis to that of epithelioid undifferentiated sarcoma. The article deals with the sometimes-delayed diagnosis in those NF1 patients with large palpable masses and chronic pain pre-existing the malignant transformation, and discusses the difficulty of the biopsy of necrotic metastases.

关键词： Necrotic Metastasis Malignant Peripheral Nerve Sheath tumor NF1 Lung Adenocarcinoma 18F-FDG PET/CT unknown primary tumor

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