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ultra-low-dose chest computed tomography with model-based iterative reconstruction in the analysis of solid pulmonary nodules:A prospective study

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World Journal of Radiology 2024年第11期16卷 668-677页

作者： Patrick W O'Regan Antonia Harold-Barry Alexander T O'Mahony Claire Crowley Stella Joyce Niamh Moore Owen J O'Connor Michael T Henry David J Ryan Michael M Maher Department of Radiology School of MedicineUniversity College CorkCork T12 AK54Ireland Department of Radiology Cork University HospitalCork T12 DC4AIreland Department of Radiology Mercy University HospitalCork T12WE28Ireland Department of Respiratory Medicine Cork University HospitalCork T12 DC4AIreland

BACKGROUND Incidental pulmonary nodules are an increasingly common finding on computed tomography(CT)scans of the thorax due to the exponential rise in CT examin-ations in everyday *** majority of incidental pulmonary nodules are benign and correctly identifying the small number of malignant nodules is ***-low-dose CT(ULDCT)has been shown to be effective in diagnosis of respiratory pathology in comparison with traditional standard dose *** hypothesis was that ULDCT chest combined with model-based iterative reconstruction(MBIR)is comparable to standard dose CT(SDCT)chest in the analysis of pulmonary nodules with significant reduction in radiation *** To prospectively compare ULDCT chest combined with MBIR with SDCT chest in the analysis of solid pulmonary *** A prospective cohort study was conducted on adult patients(n=30)attending a respiratory medicine outpatient clinic in a tertiary referral university hospital for surveillance of previously detected indeterminate pulmonary nodules on SDCT *** study involved the acquisition of a reference SDCT chest followed immediately by an ULDCT *** identification,nodule characterisation,nodule measurement,objective and subjective image quality and radiation dose were compared between ULDCT with MBIR and SDCT *** One hundred solid nodules were detected on ULDCT chest and 98 on SDCT *** was no significant difference in the characteristics of correctly identified nodules when comparing SDCT chest to ULDCT chest ***-to-noise ratio was significantly increased in the ULDCT chest in all areas except in the paraspinal muscle at the maximum cardiac diameter level(Pdose length product,computed tomography volume dose index and effective dose for the ULDCT chest protocol were 5.592 ***,0.16 mGy and 0.08 mSv *** were sign

关键词： ultra-low dose computed tomography Solid pulmonary nodules computed tomography methods Radiation dosage Adult human

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