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Clinical efficacy of intradermal type Ⅰ collagen injections in treating skin photoaging in patients from high-altitude areas

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World Journal of Clinical Cases 2024年第16期12卷 2713-2721页

作者： Bin Yang Ao He Bin-Bin Bu Gong Zhuo Qing-Zhu Zhou Jia-Hang He Liu Liu Wen-Li Huang Xian Zhao Department of Plastic and Cosmetic Surgery The Affiliated Calmette Hospital of Kunming Medical UniversityThe First People's Hospital of KunmingCalmette Hospital KunmingKunming 650224Yunnan ProvinceChina Department of Dermatology The People's Hospital of Chuxiong Yi Autonomous PrefectureChuxiong Yi Autonomous Prefecture 675099Yunnan ProvinceChina

BACKGROUND Photoaging,a result of chronic sun exposure,leads to skin damage and pigmentation *** treatments may have limitations in high-altitude areas like Yunnan *** Col Ⅰ injections stimulate collagen production,potentially improving skin *** study aims to assess the efficacy and safety of this treatment for *** To evaluate the efficacy and safety of intradermal typeιcollagen(ColΙ)injection for treating *** This prospective,self-controlled study investigated the impact of intradermal injections of ColΙon skin photodamage in 20 patients from the Yunnan *** six treatment sessions were conducted every 4 wk±3 *** and after each treatment,facial skin characteristics were quantified using a VISIA skin *** thickness data were assessed using the ultrasound probes of the Dermalab skin *** Face-Q scale was used for subjective evaluation of the treatment effect by the *** The skin thickness of the right cheek consistently increased after each treatment session compared with *** skin thickness of the left cheek significantly increased after the third through sixth treatment sessions compared with *** skin thickness of the right zygomatic region increased after the second to sixth treatment sessions,whereas that of the left zygomatic region showed a significant increase after the fourth through sixth treatment *** skin thickness of both temporal regions significantly increased after the fifth and sixth treatment sessions compared with baseline(P<0.05).These findings were also supported by skin ultrasound *** feature count for the red areas and wrinkle feature count decreased following the treatment(P<0.05).VISIA assessments also revealed a decrease in the red areas after *** Face-QSatisfaction with Facial Appearance Overall and Face-Q-Satisfaction with Skin scores significantly increased after each treatment ***

关键词： Photoaging typeιcollagen Face-Q High-altitude area Skin photodamage Patient satisfaction

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