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Revisiting the standards of cancer detection and therapy alongside their comparison to modern methods

World Journal of Methodology 2024年第2期14卷 17-37页

作者： Piotr Gromek Zuzanna Senkowska Elzbieta Pluciennik Zbigniew Pasieka Lin-Yong Zhao Adrianna Gielecinska Mateusz Kciuk Karol Klosinski Zaneta Kaluzinska-Kolat Damian Kolat Department of Functional Genomics Medical University of LodzLodz 90-752LodzkiePoland Department of Biomedicine and Experimental Surgery Medical University of LodzLodz 90-136LodzkiePoland Department of General Surgery&Laboratory of Gastric Cancer State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Gastric Cancer Center West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Molecular Biotechnology and Genetics University of LodzLodz 90-237LodzkiePoland Doctoral School of Exact and Natural Sciences University of LodzLodz 90-237LodzkiePoland

In accordance with the World Health Organization data,cancer remains at the forefront of fatal *** upward trend in cancer incidence and mortality has been observed globally,emphasizing that efforts in developing detection and treatment methods should *** diagnostic path typically begins with learning the medical history of a patient;this is followed by basic blood tests and imaging tests to indicate where cancer may be located to schedule a needle *** initiation of diagnosis is crucial since delayed cancer detection entails higher costs of treatment and ***,there is a need for novel cancer detection methods such as liquid biopsy,elastography,synthetic biosensors,fluorescence imaging,and reflectance confocal *** therapeutic methods,although still common in clinical practice,pose many limitations and are ***,there is a dynamic advancement of clinical research and the development of more precise and effective methods such as oncolytic virotherapy,exosome-based therapy,nanotechnology,dendritic cells,chimeric antigen receptors,immune checkpoint inhibitors,natural product-based therapy,tumor-treating fields,and photodynamic *** present paper compares available data on conventional and modern methods of cancer detection and therapy to facilitate an understanding of this rapidly advancing field and its future *** evidenced,modern methods are not without drawbacks;there is still a need to develop new detection strategies and therapeutic approaches to improve sensitivity,specificity,safety,and ***,an appropriate route has been taken,as confirmed by the approval of some modern methods by the Food and Drug Administration.

关键词： Cancer detection Liquid biopsy Synthetic biosensors Fluorescence imaging Reflectance confocal microscopy Elastography Cancer therapy tumor-treating fields Oncolytic virotherapy Nanotechnology

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