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检索条件"主题词=Tubulin polymerization inhibitor Antitumor agent Combretastatin-A4 analog"
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Synthesis and biological evaluation of 5,6,7-trimethoxy-1-benzylidene-3,4-dihydro-naphthalen-2-one as tubulin-polymerization inhibitors
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Chinese Chemical Letters 2015年 第5期26卷 607-609页
作者: Jun-Hang Jiang Can-Hui Zheng Chong-Qing Wang Juan Wang Wei Tian Chao Yang Yun-Long Song Yong Hu Ju Zhu You-Yun Zhou School of Pharmacy Second Military Medical University Shanghai Institute of Pharmaceutical Industry Department of Neonatology Shanghai Children's HospitalShanghai Jiao Tong University
A series of new combretastatin-a4 analogs were synthesized, in which a six-membered ring connects the linking bridge and A ring, and their tumor cell growth and tubulin-polymerization inhibitory activity were evaluate... 详细信息
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