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Barriers to the Acceptance of tuberculosis preventive treatment:A Multicenter Cross-sectional Study in China

Biomedical and Environmental Sciences 2024年第11期37卷 1303-1309页

作者： Jingjuan Ren &Fei Huang Haifeng Chen Huimin Zhang Jianwei Sun Ahui Zhao Zuhui Xu Liqin Liu Huizhong Wu Lanjun Fang Chengguo Wu Qingya Wang Wenqian Zhang Xinhua Sun Xiaoping Liu Jizheng Yuan Bohan Chen Ni Wang Yanlin Zhao National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Chinese Center for Disease Control and PreventionBeijing 102206China National Center for tuberculosis Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China Hebei Province Center for Disease Prevention and Control Hebei 050021China Institute of tuberculosis Control and Prevention Henan Center for Disease Control and PreventionHenan 450016China Hunan Institute for tuberculosis Control(Hunan Chest Hospital) Hunan 410006China Center for tuberculosis Control of Guangdong Province Guangdong 510630China Chongqing Institute for tuberculosis Prevention and Control Chongqing 404100China Tianjin Center for tuberculosis Control Tianjin 300041China Chinese Foundation for Prevention of STD and AIDS Beijing 100069China National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China

Objective We aimed to understand the willingness and barriers to the acceptance of tuberculosis(TB)preventive treatment(TPT)among people with latent TB infection(LTBI)in *** A multicenter cross-sectional study was conducted from May 18,2023 to December 31,2023 across 10 counties in *** to a national technical guide,we included healthcare workers,students,teachers,and others occupations aged 15-65 years as our research *** Overall,17.0%(183/1,077)of participants accepted *** were statistically significant differences in the acceptance rate of TPT among different sexes,ages,educational levels,and occupations(P<0.05).The main barriers to TPT acceptance were misconceptions that it had uncertain effects on prevention(57.8%,517/894),and concerns about side effects(32.7%,292/894).Conclusion An enhanced and comprehensive understanding of LTBI and TPT among people with LTBI is vital to further expand TPT in ***,targeted policies need to be developed to address barriers faced by different groups of people.

关键词： Latent tuberculosis infection tuberculosis preventive treatment Acceptance Healthcare workers Students Teachers

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