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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3368-3371页

作者： Jing Cao Xing-Liao Luo Qiang Lin Department of Anesthesiology North China Petroleum Bureau General HospitalRenqiu 062552Hebei ProvinceChina Department of Oncology North China Petroleum Bureau General HospitalHebei Medical UniversityRenqiu 062552Hebei ProvinceChina

Laparoscopic surgery is the main treatment method for patients with gastrointestinal malignant *** laparoscopic surgery is minimally invasive,its tool stimulation and pneumoperitoneum pressure often cause strong stress reactions in *** the other hand,gastrointestinal surgery can cause stronger pain in patients,compared to other *** abdominis plane block(TAPB)can effectively inhibit the transmission of nerve impulses caused by surgical stimulation,alleviate patient pain,and thus alleviate stress *** is an acting,safe,and effective sedative,which has little effect on hemodynamics and is suitable for most *** combined with remazolam can reduce the dosage of total anesthetic drugs,reduce adverse reactions,reduce stress reactions,and facilitate the rapid postoperative recovery of patients.

关键词： transversus abdominis plane block Remazolam Hemodynamics Gastrointestinal tumor surgery Oxidative stress

Application of remimazolam transversus abdominis plane block in gastrointestinal tumor surgery

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World Journal of Gastrointestinal Oncology 2023年第12期15卷 2101-2110页

作者： Jun Liu Jian-Min Tian Guo-Ze Liu Jun-Na Sun Peng-Fei Gao Yong-Qiang Zhang Xiu-Qin Yue Department of Anesthesiology and Perioperative Medicine The First Affiliated Hospital of Xinxiang Medical UniversityWeihui 453100Henan ProvinceChina

BACKGROUND transversus abdominis plane block(TAPB)is a block of the abdominal afferent nerve fibers between the internal oblique muscle and the transverse abdominal muscle achieved with local *** can effectively block the conduction of the anterior nerve of the abdominal wall and exert a good analgesic ***,the effect of combining the block with remimazolam on anesthesia in patients undergoing gastrointestinal tumor surgery is still *** To examine the effects of combining TAPB with remimazolam on the stress response and postoperative recovery of gastrointestinal tumor surgery *** A retrospective analysis was conducted on the clinical data of 102 individuals diagnosed with gastrointestinal malignancies who underwent laparoscopic surgery under general anesthesia between April 2020 and June *** patients were categorized into a control group(n=51),receiving remimazolam for general anesthesia,and an observation group(n=51),receiving TAPB combined with remimazolam for general anesthesia.A comparison was made between both groups in terms of hemodynamic parameters,stress markers,pain levels,recovery quality,analgesic effects,and adverse reactions during the perioperative *** The observation group had significantly higher heart rates at time points 1 min after induction and upon leaving the operating room than the control group(P<0.05).The mean arterial pressure at time point T1 in the observation group was significantly higher than that in the control group(P<0.05).Five minutes after extubation,the levels of the hormones adrenaline and noradrenaline in the observation group were considerably lower than those in the control group(P<0.05).At 12 h,24 h,and 48 h following surgery,the visual analog scale scores of the observation group were considerably lower than those of the control group(P<0.05).The observation group had shorter awakening and extubation times and lower Riker sedation-agitation scale scores than the con

关键词： transversus abdominis plane block Remimazolam General anesthesia Gastrointestinal tumor surgery Stress response

Effect of Subcostal Anterior Quadratus Lumborum block *** Subcostal transversus abdominis plane block after Laparoscopic Radical Gastrectomy

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Current Medical Science 2021年第5期41卷 974-980页

作者： Bing-qing NIE Ling-xia NIU En YANG Shang-long YAO Lei YANG Department of Anesthesiology Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Objective:To evaluate the analgesic effect of ultrasound-guided subcostal anterior quadratus lumborum block(QLB)for laparoscopic radical gastrectomy ***:Patients(aged 20-65 years,ASA Ⅰ-Ⅱ,and weighing 40-75 kg)scheduled for elective laparoscopic radical gastrectomy were enrolled in the current *** patients were randomly assigned to two groups by computer-generated randomization codes:an ultrasound-guided oblique subcostal transversus abdominis plane block(TAPB)group(group T,n=30)or an ultrasound-guided subcostal anterior QLB group(group Q,n=30).In both groups,bilateral ultrasound-guided oblique subcostal TAPB and subcostal anterior QLB were performed before general anesthesia with 0.25% ropivacaine 0.5 mL/*** postoperative management,all patients received patient-controlled intravenous analgesia(PCIA)with nalbuphine and sufentanil after surgery,maintaining visual analogue scale(VAS)scoresblock related complications)were observed and *** primary outcome was the perioperative consumption of ***:Compared with group T,the intraoperative consumption of remifentanil,requirement for sufentanil and the frequency of PCIA were reduced in group ***,VAS scores at all points of observation were significantly lower in group Q than in group *** in group Q were also associated with shorter time to first out-of-bed activity and flatus,and shorter length of postoperative hospital stay than group T(Pblock related complications in both ***

关键词： ultrasound-guided transversus abdominis plane block quadratus lumborum block laparoscopic radical gastrectomy

Postoperative Analgesia and Cesarean Section under General Anesthesia: Multicenter Study

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Open Journal of Anesthesiology 2024年第1期14卷 1-12页

作者： Ghislain Edjo Nkilly Raphael Okoue Ondo Pascal Christian Nze Obiang Stéphane Oliveira Jean-Marcel Mandji-Lawson Romain Tchoua Department of Anesthesia and Intensive Care Omar Bongo Ondimba Army Training Hospital (HIAOBO) Libreville Gabon Department of Anesthesia and Intensive Care Jeanne Ebori Fondation Libreville Gabon Department of Anesthesia and Intensive Care Akanda Army Training Hospital Libreville Gabon

Background: Neuraxial anesthesia with intrathecal morphine is the reference technique in cesarean section anesthesia for the management of postoperative analgesia. If there is a contraindication to this, general anesthesia is required. The objective of the study was to evaluate the analgesic effectiveness of 4 analgesic techniques performed during cesarean section under general anesthesia in two centers with different anesthetic practices (North Franche Comté Hospital and Omar Bongo Ondimba Army Training Hospital). Method: This is a retrospective and descriptive study over 2 years, from January 1, 2019 to December 31, 2020. It involved evaluating the analgesic effectiveness and tolerance of morphine in the epidural catheter, wound infiltration, intravenous analgesia and transversus Abdominous plane block (TAP block) from the post-anesthesia care unit (PACU) until the 4th post-operative day. Results: Of the 354 cesarean sections performed, 84 (11.14%) received general anesthesia. The average age was 32.27 years. Acute fetal distress was the first indication for cesarean section (45.2%), followed by hemorrhagic placenta previa (10.7%) and prolapse of the cord (8.33%). Morphine in the epidural catheter was the most used (47.6%) followed by parietal infiltration (36.9%), intravenous analgesia (13.1%) and TAP block (2.38%). The analgesic effectiveness was comparable between the techniques from postoperative day 0 to day 4. No difference in side effects. Postoperative morphine consumption was significantly reduced (p = 0.011) in the infiltration (9 mg) and TAP block (9mg) groups compared to the epidural catheter (16 mg) and intravenous analgesia (17 mg). No difference in 02 rehabilitation criteria (ambulation, first bowel movement). No difference in the occurrence of chronic pain. Conclusion: In the event of a cesarean section under general anesthesia, there are effective and well-tolerated alternatives to neuraxial anesthesia, particularly regional anesthesia

关键词： Cesarean General Anesthesia Morphine Parietal Infiltration Epidural Catheter transversus abdominis plane block Intravenous Analgesia

Anesthesia management in a pediatric patient with Becker muscular dystrophy undergoing laparoscopic surgery:A case report

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World Journal of Clinical Cases 2021年第29期9卷 8852-8857页

作者： Ling Peng Wei Wei Department of Anaesthesiology West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Patients with Becker muscular dystrophy(BMD)have a high risk of developing hyperkalemia,rhabdomyolysis,and malignant hyperthermia when exposed to volatile anesthetics and depolarizing muscle *** with BMD are also prone to respiratory depression after general ***,it is extremely challenging for anesthesiologists to manage anesthesia in BMD patients,particularly in pediatric BMD ***,we present successful anesthesia management using transversus abdominis plane block(TAPB)combined with total intravenous anesthesia(TIVA)in a pediatric BMD patient undergoing laparoscopic inguinal hernia *** SUMMARY A 2-year-old boy,weighing 15 kg,with BMD,was scheduled for laparoscopic inguinal hernia *** was used for induction,and continuous infusions of short-acting intravenous anesthetics combined with TAPB were performed for anesthesia ***,TAPB provided good postoperative *** patient underwent uneventful surgery and anesthesia,and over the 17 mo follow-up period showed no anesthesia-induced *** TAPB combined with TIVA,using short-acting intravenous anesthetic agents,can provide safe and effective anesthesia management in pediatric BMD patients undergoing short-term abdominal surgery.

关键词： transversus abdominis plane block Total intravenous anesthesia Becker muscular dystrophy Pediatric patient Case report