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Cerebral air embolism complicating transbronchial lung biopsy: A case report

World Journal of Clinical Cases 2021年第32期9卷 9911-9916页

作者： Vladimir Herout Kristian Brat Svatopluk Richter Ivan Cundrle Jr Department of Respiratory Diseases University Hospital BrnoBrno 62500Czech Republic Department of Respiratory Diseases Faculty of MedicineMasaryk UniversityBrno 62500Czech Republic International Clinical Research Center Brno 60200Czech Republic Department of Radiology and Nuclear Medicine University Hospital BrnoBrno 62500Czech Republic Department of Anesthesiology and Intensive Care St.Anne's University HospitalBrno 60200Czech Republic Department of Anesthesiology and Intensive Care Faculty of MedicineMasaryk UniversityBrno 60200Czech Republic

BACKGROUND In this case report we describe an extremely rare case of cerebral air embolism following transbronchial lung biopsy(TBLB).Only a few cases of this rare complication were described *** bronchologist should recognize this severe adverse *** recognition of this complication is mandatory in order to initiate supportive measures and consider hyperbaric oxygen *** SUMMARY In this case report we describe an extremely rare case of cerebral air embolism following *** a few cases of this rare complication were described *** patient had an incidental finding of lung tumour and pulmonary *** air embolism developed during bronchoscopy procedure,immediately after the third trans-bronchial lung biopsy sample and caused cerebral ischaemia of the right hemisphere and severe left-sided *** timely initiation of hyperbaric oxygen therapy hemiplegia didn´t resolve and the patient died several weeks *** air embolism is an extremely rare complication of *** condition should be considered in case the patient remains unresponsive or presents with acute neurological symptoms in the postintervention period since early recognition,diagnosis and hyperbaric oxygen therapy initiation are key factors determining the patient´s *** Within this report,we conclude that air/gas embolism is an extremely rare complication after TBLB,which should be considered in case the patient remains unresponsive or presents with acute neurological symptoms in the postintervention period after *** current gold standard for diagnosis is computed tomography scan of the *** recognition of this complication we suggest immediate hyperbaric oxygen therapy,if available.

关键词： transbronchial lung biopsy Cerebral air embolism Ischemic stroke Bronchoscopy Hyperbaric oxygen therapy Case report

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Endobronchial Ultrasound-guided transbronchial Needle Aspiration Increases the Yield of transbronchial lung biopsy for the Evaluation of Peribronchial Lesions

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Chinese Medical Journal 2017年第1期130卷 11-14页

作者： Cheng Chen Chuan-Yong Mu Mei-Qin Su Jing-Yu Mao Ye-Han Zhu Jian-An Huang Respiratory Department The First Affiliated Hospital of Soochow University Suzhou Jiangsu 215006 China Institute of Respiratory Diseases Soochow University Suzhou Jiangsu 215007 China

Background： Due to absence of visible endobronchial target, the diagnostic yield of flexible bronchoscopy for peribronchial lesions has been unsatisfactory. Convex probe endobronchial ultrasound （CP-EBUS） has allowed for performing real-time transbronchial needle aspiration （TBNA） of enlarged hilar and mediastinal lymph nodes and therefore could also be used as a means of diagnosing proximal peribronchial lesions. Methods： We retrospectively analyzed the results related to 72 patients who underwent CP-EBUS for peribronchial lesions without endobronchial involvement and adjacent to three-grade bronchi based on chest computed tomography （CT） scan. We recorded the images during EBUS as well as the diagnostic results of TBNA and conventional-transbronchial lung biopsy/brush （C-TBLB/b）, and final diagnoses were based on pathologic analysis and follow-up. Results： In all cases, the mass was able to be identified using EBUS in 97.2% patients （70/72） who were performed with EBUS-TBNA ＋ C-TBLB/b. Sixty-six patients had a final diagnosis, 80.0% patients （56/70） had malignancies, and 14.3% patients （10/70） had benign disease. In malignancies, the diagnostic yield of C-TBLB/b was 57.1% （32/56） and in EBUS-TBNA was 85.7% （48/56）, whereas pathologic diagnosis reached 94.6% when EBUS-TBNA was combined with C-TBLB/b. C-TBLB/b ＋ EBUS-TBNA also exhibited stronger potency of histolytic diagnosis for malignancies than either EBUS-TBNA or C-TBLB/b alone. Furthermore, there are data supporting the value of EBUS-TBNA for the diagnosis of benign lung disease. Conclusion： The combined endoscopic approach with EBUS-TBNA and C-TBLB/b is an accurate and effective method for the evaluation of peribronchial lesions, with better results than using each technique alone.

关键词： Endobronchial Ultrasound transbronchial Needle Aspiration Peribronchial Lesions transbronchial lung biopsy

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Diagnosis based on electromagnetic navigational bronchoscopyguided biopsied peripheral lung lesions in a 10-year-old girl:A case report

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World Journal of Clinical Cases 2023年第15期11卷 3651-3657页

作者： Fan-Zheng Meng Qiong-Hua Chen Man Gao Li'e Zeng Jie-Ru Lin Jing-Yang Zheng Department of Pediatrics The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Respiratory Medicine The Third Clinical Medical CollegeFujian Medical UniversityQuanzhou Women's and Children's HospitalQuanzhou 362000Fujian ProvinceChina Department of Respiratory Medicine Quanzhou Women's and Children's HospitalQuanzhou 362000Fujian ProvinceChina Department of Respiratory Medicine Quanzhou Women's and Children's HospitalThe Third Clinical Medical CollegeFujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

BACKGROUND Electromagnetic navigational bronchoscopy(ENB)is an emerging diagnostic tool that enables practitioners to biopsy peripheral lung tissues that were previously only accessible under computed tomography(CT)***,few studies have investigated ENB use in ***,we report a case of a 10-yearold girl with peripheral lung lesions who complained of a 7-d persistent *** was diagnosed with Streptococcus parasanguinis infection based on findings obtained using ENB-guided transbronchial lung biopsy(TBLB).CASE SUMMARY A 10-year-old girl presented with constitutional symptoms of cough and fever of 7 days’*** CT scans detected peripheral lung lesions and no endobronchial *** performed under the guidance of an ENB lungpro navigation system was safe,well-tolerated,and effective for biopsying peripheral lung *** of biopsied samples indicated the patient had a pulmonary Streptococcus parasanguinis infection,which was treated with antibiotics instead of more invasive treatment *** patient’s symptoms resolved after she received a 3-wk course of oral *** of pretreatment and post-treatment CT scans revealed absorption of some lung lesions within 7 mo of hospital *** ENB-guided TBLB biopsying of peripheral lung lesions in this child is a safe,well-tolerated,and effective alternative to conventional interventions.

关键词： Electromagnetic navigational bronchoscopy lungpro transbronchial lung biopsy Child Diagnosis Case report

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Chronic eosinophilic pneumonia with mucous plugs:case report

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Chinese Medical Journal 2006年第3期119卷 262-264页

作者： XIE Li-xin MO Guo-xin CHEN Liang-an LIU You-ning Department of Respiratory Medicine General Hospital of PLABeijing 100853 China

Chronic eosinophilic pneumonia （CEP）, a rare eosinophilic lung disease of unknown etiology,is characterized by peripheral blood eosinophilia, chest radiograph infiltrates, and prompt response to corticosteroid therapy. The first detailed description of CEP was described by Carrington et al in 1969. The usual symptoms are cough, dyspnea, fever, and weight loss. It is most often seen in middle aged woman and has a subacute onset. We report a case of CEP presenting with right lower lung infiltrates and mucus plugging that causing bronchus obstruction.

关键词： chronic eosinophilic pneumonia mucous plug transbronchial lung biopsy

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