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化疗药Enrofloxacin和抗球虫药toltrazuril用于水禽的临床经验

国外畜牧学(猪与禽) 1989年第1期 49-50页

作者： K.-P.Behr 陈克喜汉诺威兽医学院西德

Enrofloxacin（Bay Vp 2674,BAYTRI-LR）是一种兽用新型的喹诺酮羧酸衍生物.鸡和火鸡的体内.外和实验室、田间试验表明其为高效广谱抗菌药,尤其对革兰氏阴性菌和霉形体有效.此药在鸡和火鸡口服和非经肠投用时吸收容易、快速,0.5;小时后... 详细信息

Enrofloxacin（Bay Vp 2674,BAYTRI-LR）是一种兽用新型的喹诺酮羧酸衍生物.鸡和火鸡的体内.外和实验室、田间试验表明其为高效广谱抗菌药,尤其对革兰氏阴性菌和霉形体有效.此药在鸡和火鸡口服和非经肠投用时吸收容易、快速,0.5;小时后达最大血清浓度,口服前血清浓度半

关键词：抗球虫药鸭疫巴氏杆菌巴氏杆菌属 toltrazuril Enrofloxacin

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Control of Canine Endoparasites,Especially Isospora spp.,with Procox^(■) in Naturally Infected Puppies:Parasitological,Bacteriological and Health Parameters

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Open Journal of Veterinary Medicine 2013年第2期3卷 121-130页

作者： Barbara Anna Rauscher Sabine Schafer-Somi Monika Ehling-Schulz Karin Mostl Stefanie Handl Barbara Hinney Joachim Spergser Roland Schaper Anja Joachim Institute of Parasitology Department of PathobiologyUniversity of Veterinary Medicine ViennaViennaAustria Centre for Artificial Insemination and Embryo Transfer Department for Small Animals and HorsesUniversity of Veterinary Medicine ViennaViennaAustria Functional Microbiology IBMHDepartment of PathobiologyUniversity of Veterinary Medicine ViennaViennaAustria Institute of Virology Department of PathobiologyUniversity of Veterinary Medicine ViennaViennaAustria Institute of Animal Nutrition Department for Farm Animals and Veterinary Public HealthUniversity of Veterinary Medicine ViennaViennaAustria Clinical Microbiology and Infection Biology IBMHDepartment of PathobiologyUniversity of Veterinary Medicine ViennaViennaAustria Bayer Animal Health GmbH MonheimGermany

The effect of Procox? (Bayer, emodepside/toltrazuril suspension for dogs) against natural infections with Isospora spp. was investigated. Two groups were treated either with 0.5 ml suspension/kg of body weight (0.45 mg emodepside and 9 mg toltrazuril/kg of body weight) in the 3rd, 5th and 7th week of life (w.o.l.) (Procox? group;n = 28) or with a control anthelminthic (Dewormed Control group;n = 26). Animals were surveyed weekly from the 3rd w.o.l. by coproscopy and clinical examination. Faecal samples were examined microbiologically from the 4th to the 8th w.o.l. and faecal inflammatory markers canine calprotectin and canine S100A12 were measured in the 8th w.o.l. Specific antibody titres were evaluated in serum samples from five litters before and after vaccination against canine distemper virus and canine parvovirus 2. The prevalence of Isospora-positive animals increased to 67% in the Dewormed Control group (n = 15 puppies from four parasite-positive litters), while in the Procox? group (n = 15 puppies) it was less than 34% with significantly lower excretion (p ? was easily applied and effective;adverse effects did not occur. The level of seroconversion or titre increase upon vaccination was higher in parasite-free animals (91%) compared to Procox?-treated puppies (30%) and the Control animals (10%). Animals from parasite-free litters showed significantly different excretion patterns for haemolytic Escherichia coli and Clostridium perfringens, while there was no difference between Procox?-treated and Control animals. In some animals kept under poor hygienic conditions diarrhoea was noted in association with C. perfringens, E. coli or Salmonella. Concentrations of inflammatory markers in the faeces did not significantly differ between the Procox? and the Control group. Adequate control of parasitic and bacterial infections in suckling puppies requires both antiparasitic treatment and hygiene. Even when parasites do not cause overt effects treatment is recommended

关键词： Dog Emodepside Gut Health Isospora toltrazuril Toxocara Vaccination

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