检索结果-南通市图书馆

Much late onset of Quaternary glaciations on the tibetan Plateau:determining the age of the Shishapangma Glaciation using cosmogenic 26Al and 10Be dating

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science Bulletin 2018年第5期63卷 306-313页

作者： Yixin Chen Yingkui Li Mei Zhang Zhijiu Cui Gengnian Liu College of Urban and Environmental Sciences Peking University Beijing 100871 China Department of Geography University of Tennessee Knoxville TN 37996 USA College of Urban and Environment Science Changchun Normal University Changchun 130032 China

The onset of Quaternary glaciations is a critical event in the climate and tectonic history of the tibetan *** Shishapangma Glaciation,defined based on the till deposit from the northern slopes of ***,has been identified as the oldest glaciation on the tibetan ***,the timing of this glaciation has not been *** measured^(10)Be and^(26)Al concentrations of a set of boulders on top of this till and simulated their complex exposure-burial *** simulated results indicate that the formation age of this till is likely around 835.2±241.0 ka,representing the minimum timing of glacial onset on the tibetan *** Shishapangma Glaciation is apparently much younger than the glacial onset in many other areas of the world,such as Europe and North America,and was likely driven by the coupled effect between tectonic uplift and climate cooling during the early–middle Pleistocene transition.

关键词： Glacial onset tibetan Plateau Quaternary glaciations Cosmogenic nuclides Exposure-burial history simulation

Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in tibetan highlanders

在线全文

学校读者我要写书评

暂无评论

National Science Review 2019年第6期6卷 1201-1222页

作者： Lian Deng Chao Zhang Kai Yuan Yang Gao Yuwen Pan Xueling Ge Yaoxi He Yuan Yuan Yan Lu Xiaoxi Zhang Hao Chen Haiyi Lou Xiaoji Wang Dongsheng Lu Jiaojiao Liu Lei Tian Qidi Feng Asifullah Khan Yajun Yang Zi-Bing Jin Jian Yang Fan Lu Jia Qu Longli Kang Bing Su Shuhua Xu Key Laboratory of Computational Biology CAS-MPG Partner Institute for Computational BiologyShanghai Institute of Nutrition and HealthShanghai Institutes for Biological SciencesUniversity of Chinese Academy of SciencesChinese Academy of Sciences School of Life Science and Technology Shanghai Tech University State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology School of Life Sciences Fudan University The Eye Hospital School of Ophthalmology &Optometry Wenzhou Medical University China National Center for International Research in Regenerative Medicine and Neurogenetics Institute for Molecular Bioscience Queensland Brain Institute The University of Queensland Key Laboratory for Molecular Genetic Mechanisms and Intervention Research on High Altitude Disease of Tibet Autonomous Region School of Medicine Xizang Minzu University Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences Collaborative Innovation Center of Genetics and Development Human Phenome Institute Fudan University

Human genetic adaptation to high altitudes(>2500 m) has been extensively studied over the last few years,but few functional adaptive genetic variants have been identified, largely owing to the lack of deep-genome sequencing data available to previous studies. Here, we build a list of putative adaptive variants, including 63 missense, 7 loss-of-function, 1,298 evolutionarily conserved variants and 509 expression quantitative traits loci. Notably, the top signal of selection is located in TMEM247, a transmembrane protein-coding *** tibetan version of TMEM247 harbors one high-frequency(76.3%) missense variant, rs116983452(c.248 C > T; ***83 Val), with the T allele derived from archaic ancestry and carried by >94% of tibetans but absent or in low frequencies(tibetan populations. The rs116983452-T is strongly and positively correlated with altitude and significantly associated with reduced hemoglobin concentration(p = 5.78 × 10), red blood cell count(p = 5.72 × 10) and hematocrit(p = 2.57 × 10). In particular, TMEM247-rs116983452 shows greater effect size and better predicts the phenotypic outcome than any EPAS1 variants in association with adaptive traits in tibetans. Modeling the interaction between TMEM247-rs116983452 and EPAS1 variants indicates weak but statistically significant epistatic *** results support that multiple variants may jointly deliver the fitness of the tibetans on the plateau,where a complex model is needed to elucidate the adaptive evolution mechanism.

关键词： tibetan adaptive genetic variant high-altitude adaptation next-generation sequencing(NGS) archaic ancestry expression quantitative traits loci(eQTL) tissue-specific expression hemoglobin concentration hypoxia

Environmental significance of levoglucosan records in a central tibetan ice core

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science Bulletin 2019年第2期64卷 122-127页

作者： Chao You Tandong Yao Chao Xu Key Laboratory of tibetan Environment Changes and Land Surface Processes Institute of Tibetan Plateau Research Chinese Academy of Sciences Center for Excellence in tibetan Plateau Earth Sciences Chinese Academy of Sciences

The environmental significance of levoglucosan(LEV) records in tibetan glacier ice layers on sub-annual to annual scales, in particular their suitability as a specific biomarker for indicating past fire changes, is poorly understood at present. In this work, a continuous LEV record was reconstructed in a central tibetan ice core for the period 1990–2012. The LEV record was classified into two categories based on its LEV concentrations: background levels and extreme events. Annually-resolved LEV records and background levels in the ice core were strongly correlated with satellite observations of fire occurrence frequency over the northern Indian peninsula between 2003 and 2012, especially for strong fire events during the pre-monsoon season(March–May). In addition, peaks in LEV concentrations may represent extreme fire events in regions around the tibetan Plateau. LEV records in the ice core reflect a longterm increasing trend in fire background and also an increase in fire extreme events, across the tibetan Plateau and its surroundings. We therefore conclude that LEV records in tibetan ice cores can be used as a powerful tool for calibrating and reconstructing past fire changes over subtropical Asia.

关键词： Fire variation Levoglucosan Ice core tibetan Plateau Subtropical Asia

Genome-wide DNA methylation landscape of four Chinese populations and epigenetic variation linked to tibetan high-altitude adaptation

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2023年第10期66卷 2354-2369页

作者： Zeshan Lin Yan Lu Guoliang Yu Huajing Teng Bao Wang Yajun Yang Qinglan Li Zhongsheng Sun Shuhua Xu Wen Wang Peng Tian School of Ecology and Environment Northwestern Polytechnical UniversityXi’an 710072China State Key Laboratory of Genetic Engineering Center for Evolutionary BiologyCollaborative Innovation Center of Genetics and DevelopmentSchool of Life SciencesFudan UniversityShanghai 200438China GrandOmics Biosciences Beijing 102200China Department of Radiation Oncology Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)Peking University Cancer Hospital and InstituteBeijing 100142China Human Phenome Institute Zhangjiang Fudan International Innovation Centerand Ministry of Education Key Laboratory of Contemporary AnthropologyFudan UniversityShanghai 201203China Beijing Institutes of Life Science Chinese Academy of SciencesBeijing 100101China School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunming 650223China State Key Laboratory of Crop Stress Biology for Arid Areas and College of Agronomy Northwest A&F UniversityYangling 712100China

DNA methylation(DNAm)is one of the major epigenetic mechanisms in humans and is important in diverse cellular *** variation of DNAm in the human population is related to both genetic and environmental ***,the DNAm profiles have not been investigated in the Chinese population of diverse ***,we performed double-strand bisulfite sequencing(DSBS)for 32 Chinese individuals representing four major ethnic groups including Han Chinese,tibetan,Zhuang,and *** identified a total of 604,649 SNPs and quantified DNAm at more than 14 million Cp Gs in the *** found global DNAm-based epigenetic structure is different from the genetic structure of the population,and ethnic difference only partially explains the variation of ***,non-ethnic-specific DNAm variations showed stronger correlation with the global genetic divergence than these ethnic-specific *** methylated regions(DMRs)among these ethnic groups were found around genes in diverse biological ***,these DMR-genes between tibetan and nontibetans were enriched around high-altitude genes including EPAS1 and EGLN1,suggesting DNAm alteration plays an important role in high-altitude *** results provide the first batch of epigenetic maps for Chinese populations and the first evidence of the association of epigenetic changes with tibetans'high-altitude adaptation.

关键词： DNA methylation double-strand bisulfite sequencing Chinese ethnic groups tibetan high-altitude adaptation

De novo assembly of a tibetan genome and identification of novel structural variants associated with high-altitude adaptation

在线全文

学校读者我要写书评

暂无评论

National Science Review 2020年第2期7卷 391-402页

作者： Ouzhuluobu Yaoxi He Haiyi Lou Chaoying Cui Lian Deng Yang Gao Wangshan Zheng Yongbo Guo Xiaoji Wang Zhilin Ning Jun Li Bin Li Caijuan Bai Baimakangzhuo Gonggalanzi Dejiquzong Bianba Duojizhuoma Shiming Liu Tianyi Wu Shuhua Xu Xuebin Qi Bing Su High Altitude Medical Research Center School of Medicine Tibetan University Fukang Obstetrics Gynecology and Children Branch Hospital Tibetan Fukang Hospital State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences Kunming College of Life Science University of Chinese Academy of Sciences Chinese Academy of Sciences Key Laboratory of Computational Biology CAS-MPG Partner Institute for Computational Biology Shanghai Institute of Nutrition and Health Shanghai Institutes for Biological SciencesUniversity of Chinese Academy of Sciences School of Life Science and Technology Shanghai Tech University Center for Disease Control Tibet Autonomous Region National Key Laboratory of High Altitude Medicine High Altitude Medical Research Institute Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences Collaborative Innovation Center of Genetics and Development

Structural variants(SVs) may play important roles in human adaptation to extreme environments such as high altitude but have been under-investigated. Here, combining long-read sequencing with multiple scaffolding techniques, we assembled a high-quality tibetan genome(ZF1), with a contig N50 length of 24.57 mega-base pairs(Mb) and a scaffold N50 length of 58.80 Mb. The ZF1 assembly filled 80 remaining N-gaps(0.25 Mb in total length) in the reference human genome(GRCh38). Markedly, we detected17 900 SVs, among which the ZF1-specific SVs are enriched in GTPase activity that is required for activation of the hypoxic pathway. Further population analysis uncovered a 163-bp intronic deletion in the MKL1 gene showing large divergence between highland tibetans and lowland Han Chinese. This deletion is significantly associated with lower systolic pulmonary arterial pressure, one of the key adaptive physiological traits in tibetans. Moreover, with the use of the high-quality de novo assembly, we observed a much higher rate of genome-wide archaic hominid(Altai Neanderthal and Denisovan) shared non-reference sequences in ZF1(1.32%–1.53%) compared to other East Asian genomes(0.70%–0.98%),reflecting a unique genomic composition of tibetans. One such archaic hominid shared sequence—a662-bp intronic insertion in the SCUBE2 gene—is enriched and associated with better lung function(the FEV1/FVC ratio) in tibetans. Collectively, we generated the first high-resolution tibetan reference genome, and the identified SVs may serve as valuable resources for future evolutionary and medical studies.

关键词： long-read sequencing tibetan structural variants genetic adaptation reference genome

Solar forcing of desert vegetation and drought frequency during the last 2700 years in the interior Qaidam Basin, northeastern tibetan Plateau

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2020年第4期63卷 561-574页

作者： Quan LI Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China

Knowledge of long-term change in vegetation and climate in semi-arid/arid regions is essential for the study of current climate and development of mitigation strategies against severe drought. Here, a fossil pollen record of annually-varved core from Sugan Lake in interior Qaidam Basin was quantitatively analyzed to reconstruct changes in vegetation, floristic diversity and drought frequency. Results of biomization suggested that regional vegetation was desert vegetation with three short-term occupations of temperate steppe/xerophytic shrub during the last 2700 years. Floristic diversity generally increased/decreased with the expansion/degradation of desert vegetation. Moisture fluctuations showed three distinct stages(extremely dry between 742 BC and ~AD500, relatively wet with an increasing trend between ~AD500 and 1200 and relatively wet with frequent fluctuations after AD1200), interrupted by 14 drought events. Spectral analysis and continuous wavelet transform of moisture variation revealed 200-and 120-year cycles. According to cross-wavelet transform analysis, major drought frequency of ~200-year was explicitly correlated to solar activity. It's suggested that the centennial-scale drought frequency was mainly driven by solar activity, through modulation of large-scale atmospheric circulation. Furthermore, the effect of surface temperature–evaporation and uplifting/subsiding air flow should be notable. The climatic drought in interior Qaidam Basin could be intensified under the continuous global warming.

关键词： Pollen Vegetation change Drought frequency Qaidam Basin Northeastern tibetan Plateau

Impact of Surface Potential Vorticity Density Forcing over the tibetan Plateau on the South China Extreme Precipitation in January 2008. Part Ⅰ:Data Analysis

在线全文

学校读者我要写书评

暂无评论

Journal of Meteorological Research 2019年第3期33卷 400-415页

作者： Tingting MA Guoxiong WU Yimin LIU Zhihong JIANG Jiahui YU Key Laboratory of Meteorological Disaster of Ministry of Education/Joint International Research Laboratory of Climate and Environmental Change Nanjing University of Information Science & Technology Nanjing 210044 State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 College of Earth Science University of Chinese Academy of Sciences Beijing 100049 Center for Excellence in tibetan Plateau Earth Sciences Chinese Academy of Sciences Beijing 100101

The external source/sink of potential vorticity (PV) is the original driving force for the atmospheric circulation. The relationship between surface PV generation and surface PV density forcing is discussed in detail in this paper. Moreover, a case study of the extreme winter freezing rain/snow storm over South China in January 2008 is performed, and the surface PV density forcing over the eastern flank of the tibetan Plateau (TP) has been found to significantly affect the precipitation over South China in this case. The TP generated PV propagated eastward in the middle troposphere. The associated zonal advection of positive absolute vorticity resulted in the increasing of cyclo-nic relative vorticity in the downstream region of the TP. Ascending air and convergence in the lower troposphere developed, which gave rise to the development of the southerly wind. This favored the increasing of negative meridio-nal absolute vorticity advection in the lower troposphere, which provided a large-scale circulation background conducive to ascending motion such that the absolute vorticity advection increased with height. Consequently, the ascending air further strengthened the southerly wind and the vertical gradient of absolute vorticity advection between the lower and middle troposphere in turn. Under such a situation, the enhanced ascending, together with the moist air transported by the southerly wind, formed the extreme winter precipitation in January 2008 over South China.

关键词： potential vorticity density (PVD) absolute vorticity advection tibetan Plateau winter precipitation

Pleistocene magnetic susceptibility and paleomagnetism of the tibetan loess and its implications on large climatic change events

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2001年第S1期44卷 227-232页

作者：颜茂都方小敏陈诗越杨胜利吕连清李吉均安芷生 MOE National Laboratory of Western China’s Environmental Systems & Department Geography Lanzhou University Lanzhou China State Key Laboratory of Loess and Quaternary Geology Institute of Earth Environment of Chinese Academy of Sciences Xi’an China

Ganzi loess represents the oldest tibetan loess, its formation is the key to determining the readjustment of tibetan atmospheric circulation and the relationship between tibetan uplift and global climatic change. Detailed magnetostratigraphic study shows that the Ganzi loess was formed at about 1.13 MaBP. It also reveals that there are two notable climatic events occurring in 0.95-0.92 Ma and 0.65-0.5 Ma respectively. They both demonstrate that the tibetan atmospheric circulation was readjusted and the tibetan Plateau entered the cryosphere at 21.13 Ma, and the tibetan glaciation might reach its maximum at ~ 0.65-0.5 Ma.

关键词： : tibetan Plateau loess uplift atmospheric circulation climatic change.

Characterizing the Mass Elevation Effect across the tibetan Plateau

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2018年第12期15卷 2651-2665页

作者： HAN Fang ZHANG Bai-ping ZHAO Fang WAN Li TAN Jing LIANG Tian School of Civil and Architectural Engineering, Shandong University of Technology Institute of Geographic Sciences and Natural Resources Research, State Key Laboratory of Resources and Environmental Information System, Chinese Academy of Sciences College of Environment and Planning, Henan University Chinese Research Academy of Environmental Sciences Beijing Aerospace TITAN Technology Co., Ltd School of Civil and Architectural Engineering Shandong University of TechnologyZibo 255000China Institute of Geographic Sciences and Natural Resources Research State Key Laboratory of Resources and Environmental Information SystemChinese Academy of SciencesBeijing 100101China College of Environment and Planning Henan UniversityKaifeng 455000China Chinese Research Academy of Environmental Sciences Beijing 100012China Beijing Aerospace TITAN Technology Co. LtdBelling 100083China

It is over 110 years since the term Mass Elevation Effect(MEE) was proposed by A. D. Quervain in 1904. The quantitative study of MEE has been explored in the tibetan Plateau in recent years; however, the spatial distribution of MEE and its impact on the ecological pattern of the plateau are seldom known. In this study, we used a new method to estimate MEE in different regions of the plateau, and, then analyzed the distribution pattern of MEE, and the relationships among MEE, climate, and the altitudinal distribution of timberlines and snowlines in the Plateau. The main results are as follows:(1) The spatial distribution of MEE in the tibetan Plateau roughly takes on an eccentric ellipse in northwestsoutheast trend. The Chang Tang Plateau and the middle part of the Kunlun Mountains are the core area of MEE, where occurs the highest MEE of above 11℃; and MEE tends to decreases from this core area northwestward, northeastward and southward;(2) The distance away from the core zone of the plateau is also a very important factor for MEE magnitude, because MEE is obviously higher in the interior than in the exterior of the plateau even with similar mountain base elevation(MBE).(3) The impacts of MEE on the altitudinal distribution of timberlines and snowlines are similar, i.e., the higher the MEE, the higher timberlines and snowlines. The highest timberline(4600–4800 m) appears in the lakes and basins north of the Himalayas and in the upper and middle reach valleys of the Yarlung Zangbo River, where the estimated MEE is 10.2822℃–10.6904℃. The highest snowline(6000–6200 m) occurs in the southwest of the Chang Tang Plateau, where the estimated MEE is 11.2059°C–11.5488℃.

关键词： Mass Elevation Effect (MEE) Distribution Pattern Timberline Snowline tibetan Plateau