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Extrapleural solitary fibrous tumor of the Thyroid gland: A case report and review of literature

World Journal of Clinical Cases 2020年第4期8卷 782-789页

作者： Yong Joon Suh Jung Ho Park Jae Hyeon Jeon Sanchir-Erdene Bilegsaikhan Department of Breast and Endocrine Surgery Hallym University Sacred Heart HospitalGyeonggi-do 14068South Korea Department of Biomedical Science Hallym UniversityChuncheon 24252South Korea

BACKGROUND Solitary fibrous tumor(SFT)is an uncommon mesenchymal neoplasm that arises from the pleura.A few SFTs have also been described in extrapleural sites.However,SFT of the Thyroid gland is rare.Here,we report a case of extrapleural SFT on the Thyroid gland,in addition to a literature review.CASE SUMMARY A 59-year-old man visited our hospital in July 2017 complaining of a large mass in his neck.His thyroid function test results,including antibody levels,were within the normal limits.Ultrasonography showed a 4.7 cm×4.0 cm×3.2 cm solitary mass of intermediate suspicion in the left thyroid lobe.A fine-needle aspiration biopsy was subsequently performed.The pathologist reported a benign follicular lesion.However,the size of this nodule increased to 5.5 cm×5.0 cm×3.4 cm by April 2018.After a multidisciplinary discussion,a left lobectomy was performed in May 2018.The specimen showed a well-demarcated,partly encapsulated,soft nodule of whitish and tan/brown color on the cut surface.Light microscopy revealed high cellularity with moderate cytologic atypia.The mitotic count was 5/10 high-power fields.There was no tumor necrosis or lymphovascular invasion.The tumor was CD34-positive and signal transducer and activator of transcription 6-positive.Neither thyroid transcription factor-1 nor cytokeratin expression was detected.The Ki-67 showed intermediate proliferative activity.The final diagnosis was extrapleural SFT of the Thyroid gland with a clear resection margin.The patient was discharged without complication three days after the surgery.CONCLUSION In the literature,extrapleural SFT of the Thyroid gland has been reported to behave indolently with the capacity for recurrence and rare metastasis,although surgical resection is the treatment of choice.Understanding this disease entity is important for accurate diagnosis and proper management.

关键词： Solitary fibrous tumor Mesenchymal neoplasm Thyroid gland Surgery Case report Review

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Colorectal cancer metastases to the Thyroid gland:A case report

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World Journal of Gastrointestinal Surgery 2020年第3期12卷 116-122页

作者： Patricia Ciriano Hernández Carlos Martínez Pinedo Enrique Calcerrada Alises Esther García Santos Susana Sánchez García Rafael Picón Rodríguez Elisa Jiménez Higuera Daniel Sánchez Peláez Violeta Herrera Montoro esús Martín Fernández Department of Surgery Hospital General Universitario de Ciudad RealCiudad Real 13005Spain Department of Pathology Hospital General Universitario de Ciudad RealCiudad Real 13005Castilla La ManchaSpain

BACKGROUND Secondary malignancies of the Thyroid gland are a rare finding in clinical practice.In addition,colorectal metastasis to the thyroid(CMT)is even more infrequently diagnosed.The source of the primary tumor follows demographic and ethnic patterns,which reflects the most prevalent malignancies in the different populations.Colorectal cancer is one of the most common types of cancer worldwide;nevertheless,CMT is infrequently diagnosed.Most of them are identified during the follow-up of gastrointestinal primary malignancies.Due to the improvement of image techniques,oncological treatment,and follow-up,survival and consequent diagnosis of metastatic disease are more frequent.Those facts make this entity a diagnostic and therapeutic challenge,due to the lack of information and the difficulties performing clinical trials and research.CASE SUMMARY Here,we present a case report of a patient diagnosed with CMT of adenocarcinoma of the rectum evidenced during follow-up,4 years after neoadjuvant chemoradiotherapy,who had subsequent curative surgical treatment of the primary tumor and inter-current lung bilateral metastases.CONCLUSION thyroid metastases of extra-thyroid origin are an uncommon finding,even rarer in cases of CMT.The diagnostic process,as well as survival of oncologic patients is improving,and consequently the number of metastases to the Thyroid gland is increasing.

关键词： Colorectal cancer metastases Thyroid gland Case report thyroid metastases

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Metastasis of esophageal squamous cell carcinoma to the Thyroid gland with widespread nodal involvement: A case report

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World Journal of Clinical Cases 2020年第19期8卷 4588-4594页

作者： Xing Zhang Xin Gu Jia-Gen Li Xian-Jie Hu Department of thyroid and Breast Surgery The Affiliated People's Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina Department of Pathology The Affiliated People's Hospital of Ningbo UniversityNingbo 315040Zhejiang ProvinceChina

BACKGROUND Esophageal cancer is one of the most common causes of cancer-related death.Some patients with esophageal cancer have distant metastases at the time of diagnosis,but metastasis to the Thyroid gland(MTG)and multifocal thyroid lesions alone are extremely rare.CASE SUMMARY In this case report,we present a case of a 69-year-old male with esophageal MTG.The patient visited our hospital for a routine body check-up,which revealed multifocal nodules in his thyroid lobes and enlarged cervical lymph nodes.A fine needle aspiration biopsy showed malignancies in both thyroid lesions and lymph nodes.The patient was initially diagnosed with primary bilateral thyroid cancer that spread to his lymph nodes,and a total thyroidectomy was performed.The histology showed MTG and therefore,a diagnostic work-up was implemented to determine the primary tumor.A fluorine-18-deoxyglucose positron emission tomography scan showed that the lower part of the esophagus and the lymph nodes in the neck,chest,and abdomen were involved.An esophagogastroscopy and corresponding pathology revealed distal esophageal squamous cell carcinoma.The esophageal MTG diagnosis was confirmed with pathological immunohistochemistry.CONCLUSION This case report highlights the difficulty in diagnosing esophageal MTG.Patients may have no malignancy history and be asymptomatic.Further diagnostic procedures are necessary after MTG is confirmed by cytology or histology,and the final diagnosis should be made according to the identification of the primary malignancy combined with pathological immunohistochemistry findings.

关键词： Esophageal squamous cell carcinoma Metastasis Thyroid gland thyroidectomy Lymph nodes Case report

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Effects　of　Low　Concentration　Samarium　Chloride　on　theUltrastructure　and　Function　of　Rat　thyroid　gland

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Journal of Rare Earths 1996年第2期14卷 150-153页

作者：周莉黄可欣王晓辉聂毓秀朱秀雄 Basic Medical College Norman Bethune University of Medical Sciences Changchun 130021 China

The levels of thyroxine (T3, T4) and thyroid stimulating hormone (TSH) in rat serum were measured by radioimmunoassay, and also ultrastructure of the Thyroid gland and adenohypophyseal cell were examined by transmission electronic microscopy (TEM) after low concentration (0. 05 mg/kg) of samarium chloride (SmCl3) administration by intraperitoneal, oral and tail intravenous routes. The results showed that the level of T4 in rat serum increased and the level of TSH unchanged by the intraperitoneal administration, and the levels of T3, T4 and TSH did not increase by the oral and tail intravenous administration. The evidences mentioned above were in accord with the morphological changes of thyroid follicular epithelial cells andadenohypophysis thyrotroph observed under electronic microscope in a sense.

关键词： Thyroid gland Adenohypophysis thyrotroph Samarium chloride Radioimmunoassay,Ultrastructure

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Mobile Phone Use and Risk of Thyroid gland Lesions Detected by Ultrasonography

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Open Journal of Radiology 2016年第2期6卷 140-146页

作者： Naglaa M. Elsayed Saddig D. Jastaniah Diagnostic Radiology Department King Abdulaziz University Jeddah Saudia Arabia Diagnostic Radiology Department Faculty of Medicine Cairo University Cairo Egypt

In recent years, widespread use of mobile phones has led to a public debate about possible harmful effects on human health. A lot of researchers studied the possible effect of radiofrequency energy (RFE) emitted from cell phones on the human body. Up to our knowledge no one studied the effect of these waves on the Thyroid gland by Ultrasonography (US). Our aim was to investigate the possible effects of EMR arising from cell phones on the Thyroid gland using US. A prospective study was done on 180 participants, 110 females and 70 males, ranging in age from 15 to 65. A constructed questionnaire was distributed among them before performing US of the neck. Demographic data along with US findings were collected and statistically analyzed. A total of 46.7% of our participants had abnormal findings of the Thyroid gland more in non smart phone users and more in females. The commonest abnormality was multinodular goiter (54%). Expanded researches are still needed to answer the question about the hazards of RFE on human health. All efforts should be made to encourage users of cellular phone to follow mobile device recommendations of manufacturers and avoid its possible hazards as possible.

关键词： Radiofrequency Energy Mobile Phones Ultrasound Thyroid gland Nodules

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Metastasis of liver cancer to the thyroid after surgery:A case report

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World Journal of Clinical Cases 2022年第15期10卷 5036-5041页

作者： Hao-Chen Zhong Zhao-Wei Sun Guang-Hua Cao Wei Zhao Kai Ma Bing-Yuan Zhang Yu-Jie Feng Medical College Qingdao UniversityQingdao 266071Shandong ProvinceChina Department of Hepatobiliary and Pancreatic Surgery Huikang Hospital of QingdaoQingdao 266000Shandong ProvinceChina Department of Hepatobiliary and Pancreatic Surgery The Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina

BACKGROUND Secondary thyroid malignancies are rarely reported,especially thyroid metastasis after resection of hepatocellular carcinoma(HCC).We report a patient with thyroid metastasis after resection of HCC.CASE SUMMARY A 42-year-old female underwent partial hepatectomy for HCC three years ago.She attended hospital because of neck discomfort.After various examinations,she was diagnosed with metastatic HCC.She survived after surgical resection of the affected side of the thyroid.CONCLUSION Although secondary malignant tumor of the thyroid is classified as distant metastasis,surgical resection is still necessary according to the patient's condition.

关键词： Hepatocellular carcinoma Liver cancer Thyroid gland Metastasis Surgery Case report

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Factors influencing postoperative anxiety and depression following Iodine-131 treatment in patients with differentiated thyroid cancer:A cross-sectional study

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World Journal of Psychiatry 2023年第7期13卷 486-494页

作者： Ying-Rui Su Xiao-Peng Yu Li-Qun Huang Long Xie Jin-Shun Zha Department of Nuclear Medicine The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

BACKGROUND Differentiated thyroid cancer(DTC)often seriously impacts patients’lives.Radionuclide Iodine-131(131I)is widely used in treating patients with DTC.However,most patients know little about radionuclide therapy,and the treatment needs to be performed in a special isolation ward,which can cause anxiety and depression.AIM To explore anxiety and depression status and their influencing factors after 131I treatment in patients with DTC.METHODS A questionnaire survey was conducted among postoperative patients with DTC who received 131I treatment at our hospital from June 2020 to December 2022.General patient data were collected using a self-administered demographic characteristics questionnaire.The self-rating depression scale and self-rating anxiety scale were used to determine whether patients were worried about their symptoms and the degree of anxiety and depression.The patients were categorized into anxiety,non-anxiety,depression,and non-depression groups.Singlevariable and multiple-variable analyses were used to determine the risk factors for anxiety and depression in patients with thyroid cancer after surgery.RESULTS A total of 144 patients were included in this study.The baseline mean score of self-rating anxiety and depression scales were 50.06±16.10 and 50.96±16.55,respectively.Notably,48.62%(70/144)had anxiety and 47.22%(68/144)of the patients had depression.Sex,age,education level,marital status,household income,underlying diseases,and medication compliance significantly differed among groups(P<0.05).Furthermore,multivariate logistic regression analysis showed that education level,per capita monthly household income,and medication compliance level affected anxiety(P=0.015,0.001,and 0.001 respectively).Patient’s sex,marital status,and underlying diseases affected depression(P=0.007,0.001,and 0.009,respectively).CONCLUSION Nursing interventions aiming at reducing the risk of anxiety and depression should target unmarried female patients with low education level,low family income,underlying diseases,and

关键词： Iodine-131 Thyroid gland Neoplasms Anxiety Depression Prognosis

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thyroid fine needle aspiration

Thyroid fine needle aspiration

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2013年

作者： Grace C. H. Yang.

ISBN: (纸本)9781107022201

This practical text and color atlas tells the story of 350 patients, covering a wide range of thyroid lesions with high quality composite images that correlate cytology with histology, and radiology with pathology. Each case includes clinical presentation and final pathology. Concise, easy-to-read text enables readers to quickly find the information they need for accurate diagnosis. 'Lookalike' le

关键词： Thyroid gland Diseases Cytodiagnosis. Thyroid gland Needle biopsy. thyroid Neoplasms diagnosis. Biopsy, Fine-Needle methods. Thyroid gland pathology.

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Assessment of LLLT systemic effects on thyroid hormones function after dental titanium implant installation:An experimental rabbit model

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Natural Science 2013年第8期5卷 933-940页

作者： Luciano Mayer Fernando Vacilotto Gomes Carlos Eduardo Baraldi Joao Batista Blessmann Weber Marília Gerhardt de Oliveira Department of Oral and Maxillofacial Surgery School of DentistryPontifícia Universidade Católica do Rio Grande do SulPorto AlegreBrazil Oral and Maxillofacial Surgery and Traumatology—Department of Surgery Universidade Federal do Rio Grande do SulSchool of DentistryRio Grande do SulBrazil Oral and Maxillofacial Surgery Service Hospital Cristo Redentor—Grupo Hospitalar ConceicaoPorto AlegreBrazil

This study aimed to assess the systemic effect of LLLT on Thyroid gland functioning and consequently on calcium regulation through Triiodothyronine (T3) and Thyroxine (T4) measurements in rabbits’ serum. A total of thirty two New Zealand male rabbits were randomly distributed in four groups with eight animals each: control group C (nonirradiated animals), group EI (5 J/cm2 per session), group EII (10 J/cm2 per session) and group EIII (20 J/cm2 per session). All animals underwent lower left incisor extraction followed by immediate insertion of an osseintegrated implant, providing an equality of initial clinical condition between the groups. The experimental groups were irradiated with aluminium gallium arsenide diode laser (GaAlAs, λ = 830 nm, 50 mW, CW), during 13 days at each 48 hours, totalizing 7 sessions. Laboratorial T3 and T4 measurements were done in four distinct moments (before surgical procedure, immediately after surgical procedure, after the first LLLT session and after the last LLLT session) in all animals. The results obtained showed statistically significant differences in Triiodothyronine values between the groups throughout the experiment. It was concluded that the LLLT, in the protocol of irradiation used in this study, promoted a significantly alteration on rabbits’ serum hormonal levels.

关键词： Thyroid gland Laser Therapy Low Level thyroid Hormones Dental Implant

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Definition of retrosternal thyroid growth

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Open Journal of Clinical Diagnostics 2012年第2期2卷 36-39页

作者： Ernst GEising Sandra Rosenbaum-Krumme Walter Jentzen Alfred Godecke Andreas Bockisch Radprax ArnsbergGermany Clinic for Nuclear Medicine University of Duisburg-EssenDuisburg and EssenGermany

The diagnosis of a retrosternal thyroid growth (RTG) causes extended surgical exploration and a different surgical treatment planning (partial sternotomy, thoracotomy) and is usually made by the help of thyroid scintigraphy and ultrasonography. But both examinations have problems in determining the retrosternal thyroid extend in the complex anatomy of sternal bone and often pathologically altered manubrioclavicular joints (MCJ). This study evaluates the variation of anatomical structures in the upper sternal region, the position of the sternal markers during scintigraphy, and the frequency of enhanced bone metabolism of the MCJs. For this aim, the positions of the upper edges of the MCJs were measured by X-ray fluoroscopy in 50 consecutive patients. To prove the exactness of an external marker as used in thyroid scintigraphy, the variation of the marker position was also determined. The activity in the MCJs was measured semiquantitatively with bone scintigraphy in further 100 patients (mean age: 62.3 yrs, SD: 14.2 yrs). As results, the upper edges of the medial clavicular edges exceed the upper margin of the sternal edge up to 2.7 cm. The distance between the medial clavicular edges ranged from 2.3 - 5.6 cm. The position of the sternal marker was correct in the horizontal deviation (mean: 0.1 cm, SD: 0.48 cm) but too high in the vertical position (mean: 2.2 cm, SD: 0.67 cm). During bone scintigraphy, the MCJs showed no enhanced activitity in 75/200 joints, medium activity in 96/200 joints, and strong enhanced activity in 29/200 joints. In consequence, a high variability in the position of the anatomical structures has to be considered together with a high amount of degenerative alterations. The position of the sternal marker was inappropriate in the vertical direction and overestimated a possible retrosternal growth.

关键词： Thyroid gland thyroid Scintigraphy Manubrioclavicular Joints

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