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Severe thromboembolic complication Revealing a Nephrotic Syndrome Due to Segmental and Focal Hyalinosis: A Case Report

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Open Journal of Nephrology 2021年第3期11卷 450-457页

作者： Sah Dit Baba Coulibaly Magara Samaké Aboubacar Sidiki Fofana Seydou Sy Hamadoun Yattara Nanko Doumbia Katilé Drissa Moctar Coulibaly Kodio Atabieme Djénéba Maiga Aboudou Messoum Dolo Nouhoum Coulibaly Hamat Ibrahim Saharé Fongoro Konaté Anselme Nephrology Unit of Somino DOLO Hospital Mopti Mali Nephrology Unit of the Fousseyni DAOU Hospital Kayes Mali National Center for Scientific and Technological Research (CNRST) Bamako Mali Faculty of Medicine of Bamako Bamako Mali Department of Nephrology and Haemodialysis University Teaching Hospital of Point-G Bamako Mali Medicine Department of Mali Hospital Bamako Mali Gastrohepato-Enterology Unit of the Fousseyni DAOU Hospital Kayes Mali Nephrology Unit of the Mali GAVARDO Hospital of Sebenicoro Bamako Mali Nephrology Unit of Sikasso Hospital Sikasso Mali Department of Nephrology-Hemodialysis National General Reference Hospital N'Djamena Chad Department of Gastro-Hepato-Enterology Gabriel Touré University Hospital Bamako Mali

Adult Nephrotic Syndrome (NS) is defined by proteinuria > 3 g/24h or 50 mg/kg/day, hypoprotidemia < 60 g/24h, hypoalbuminemia < 30 g/L. It is a disease with high thromboembolic risk. Peripheral vein thrombosis is comm... 详细信息

Adult Nephrotic Syndrome (NS) is defined by proteinuria > 3 g/24h or 50 mg/kg/day, hypoprotidemia thromboembolic risk. Peripheral vein thrombosis is common, while its association with pulmonary localizations has been more rarely reported. We report a case of nephrotic syndrome revealed by an association of pulmonary embolism, renal vein and inferior vena cava thrombosis. The diagnosis was confirmed by thoracic angioscan. Renal biopsy revealed Focal Segmental Hyalinosis (FSH). An anti-coagulant treatment and an anti-proteinuric treatment were instituted based on a calcium channel blocker (amlodipine) associated with the conversion enzyme inhibitor (perindopril).

关键词： thromboembolic complication Nephrotic Syndrome Segmental and Focal Hyalinosis Bamako/Mali

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Safety of laparoscopic surgery in digestive diseases with special reference to antithrombotic therapy: A systematic review of the literature

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World Journal of Clinical Cases 2018年第14期6卷 767-775页

作者： Takahisa Fujikawa Kenji ando Department of Surgery Kokura Memoria Hospital Department of Cardiology Kokura Memorial Hospital

AIMTo elucidate the effect of antithrombotic therapy （ATT） on bleeding and thromboembolic complications during or after laparoscopic digestive *** articles or internationally accepted abstracts between 2000 and 2017 were searched from PubMed, Cochrane Database, and Google Scholar, and studies involving laparoscopic digestive surgery and antiplatelet therapy （APT） and/or anticoagulation therapy （ACT） were included after careful review of each study. Data such as study design, type of surgical procedures, antithrombotic drugs used, and surgical outcome （both bleeding and thromboembolic complications） were extracted from each *** published articles and two internationally accepted abstracts were eligible for inclusion in the systematic review. Only one study concerning elective laparoscopic cholecystectomy in patients with peri-operative heparin bridging for ACT showed that the risk of postoperative bleeding was higher compared with those without ACT. The remaining 14 studies reported no signifcant differences in the incidence of bleeding complications between the ATT group and the group without ATT. The risk of thromboembolic events （TE） associated with laparoscopic digestive surgery in patients receiving ATT was not signifcantly higher than those with no ATT or interrupted *** T et al . Laparoscopic digestive surgery and antithrombotic therapyCONCLUSIONLaparoscopic digestive surgery in ATT-burdened patients for prevention of bleeding and TE showed satisfactory results. The risk of hemorrhagic complication during or after these procedures in patients with continued APT or heparin bridging was not signifcantly higher than in patients with no ATT or interrupted APT.

关键词： thromboembolic complication Bleeding complication Laparoscopic surgery Anticoagulation therapy Digestive surgery Antithrombotic therapy Antiplatelet therapy

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Safety of liver resection in patients receiving antithrombotic therapy:A systematic review of the literature

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World Journal of Hepatology 2021年第7期13卷 804-814页

作者： Takahisa Fujikawa Department of Surgery Kokura Memorial HospitalFukuoka 802-8555Japan

BACKGROUND Little is unknown about the effect of chronic antithrombotic therapy(ATT)on bleeding complication during or after *** addition,the safety and effectiveness of chemical prevention for venous thromboembolism(VTE)is still *** To clarify the effect of ATT on thromboembolism and bleeding after liver *** Articles published between 2011 and 2020 were searched from Google Scholar and PubMed,and after careful reviewing of all studies,studies concerning ATT and liver resection were *** such as study design,type of surgery,type of antithrombotic agents,and surgical outcome were extracted from the *** Sixteen published articles,including a total of 8300 patients who underwent hepatectomy,were eligible for inclusion in the current *** studies regarding patients undergoing chronic ATT showed that hepatectomy can be performed safely,and three studies have also shown the safety and efficacy of preoperative continuation of *** chemical prevention for VTE,some studies have shown a potentially high risk of bleeding complications in patients undergoing chemical thromboprophylaxis;however,its efficacy against VTE has not been shown statistically,especially among Asian *** Hepatectomy in patients with chronic ATT can be performed safely without increasing the incidence of bleeding complications,but the safety and effectiveness of chemical thromboprophylaxis against VTE during liver resection is still controversial,especially in the Asian *** a clear protocol or guideline requires further research using reliable studies with good design.

关键词： Liver resection Bleeding complication Antithrombotic therapy thromboembolic complication Thromboprophylaxis

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