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Current Medical Science 2020年第2期40卷 380-388页

作者： Meng-yun LI Chao CHEN Zheng gang WANG Jian-juan KE Xiao-bo FENG Department of Anesthesiology Zhongnan HospitalWuhan UniversiryWuhan 430071China

The intravenous use of nalmefene has been found to exert neuroprotective effect in patients with severe traumatic brain injury and acute cerebral infarction;nonetheless,it is unknown whether nalmefene alleviates delayed neurocognitive *** purpose of the current research was to clarify the impact of nalmefene on delayed neurocognitive recovery in aged patients experiencing video-assisted thoracic surgery(VATS)with intraoperative use of one lung ventilation(OLV).The present study involved 120 paticents undergoing selective VATS,randomized to accept low-dose nalmefene(N1 group,n=40),high-dose nalmefene(N2 group,1n=40)or equal volume of physiologic saline(control group,1=40).A battery of neuropsychological tests were used to estimate cognitive function I day before surgery(o)and 10 days after surgery or before discharge(t).Regional cerebral oxygen saturation(rSO2)was detected 5 min before induction(t),5 min after induction(1),15 and 60 min after onset of OLV(62 and 13),and 15 min after termination of OLV(4).The plasma values of interleukin(IL)-1β,IL-6,tumor necrosis factor(TNF)-a1 and adiponectin(ADP)were also detected prior to induction of anesthesia(T0),1 h,2 h and 6 h after surgery(TI,T2,T3).On 1,delayed neurocognitive recovery occurred in 5/40(12.5%)patients of NI group,in 5/40(12.5%)patients of N2 group and in 13/40(32.5%)patients of control group(PNl group>control group(P<0.05).The result of our present research supports the hypothesis that the perioperative intravenous t

关键词： nalmefene one lung ventilation elderly patients delayed neurocognitive recovery perioperative neurocognitive disorders thoracic surgery

Gastroparesis after video-assisted thoracic surgery:A case report

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World Journal of Clinical Cases 2023年第8期11卷 1862-1868页

作者： Hang An Yu-Cun Liu Department of General surgery Peking University First HospitalBeijing 100034China

BACKGROUND Video-assisted thoracic surgery(VATS)lobectomy is a common treatment for patients with early-stage lung *** patients can experience slight gastrointestinal discomfort after lobectomy for a *** is a gastrointestinal disorder that can be severe;it is associated with an increased risk of aspiration pneumonia and impaired postoperative ***,we report a rare case of gastroparesis after VATS *** SUMMARY A 61-year-old man underwent VATS right lower lobectomy uneventfully but had an obstruction of the upper digestive tract 2 d after *** gastroparesis was diagnosed after emergency computed tomography and oral iohexol X-ray *** gastrointestinal decompression and administration of prokinetic drugs,the patient’s gastrointestinal symptoms *** perioperative medication was applied according to the recommended dose and there was no evidence of electrolyte imbalance,intraoperative periesophageal vagal nerve injury was the most likely underlying cause of *** Although gastroparesis is a rare perioperative complication following VATS,clinicians should be on the alert when patients complain about gastrointestinal *** surgeons resect paraesophageal lymph nodes with electrocautery,excessive ambient heat and compression of paraesophageal hematoma might induce vagal nerve dysfunction.

关键词： Gastroparesis Delayed gastrointestinal emptying Video-assisted thoracic surgery Lobectomy thoracic surgery Case report

Application of Video-Assisted thoracic surgery in the Standard Operation for Lung Tumors

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Clinical oncology and cancer researeh 2010年第5期7卷 310-316页

作者： Ju-wei MU Ning LI Fang LU You-sheng MAO Qi XUE Shu-geng GAO Jun ZHAO Da-li WANG Zhi-shan LI Wen-dong LEI Yu-shu GAO Liang-ze ZHANG Jin-feng HUANG Kang SHAO Kai SU Kun YANG Jian LI Gui-yu CHENG Ke-lin SUN Jie HE Department of thoracic Cancer Institute &Hospita Surgical Oncology of Medical Sciences Beijing Chinese Academy 100021. China.

OBJECTIVE To evaluate the indication and short-term outcomes of video assisted thoracic surgery （VATS） for lung tumors. METHODS Data of 306 consecutive patients undergoing VATS pulmonary resection between January 2009 and August 2010 in Cancer Institute ＆ Hospital, Chinese Academy of Medical Sciences were retrospectively reviewed. RESULTS There were 7 patients who underwent open thoracotomy, accounting for 2.29% （7/306）. The overall morbidity rate of complications and the mortality rate induced by VATS was 1.63% （5/306） and 0.33% （1/306）, respectively. There were no significant differences in morbidity and mortality rate between the patients receiving the VATS and the patients receiving the OT. The overall hospitalization, postoperative length of stay （LOS） and chest tube duration in the VATS lobectomy group （n = 167） were shorter than those in the open thoracotomy （OT）, but the operative time in the VATS group was longer than that in the OT group （n = 124）. There were no significant differences in the number of station of lymph nodal dissection （LND） and number of LND in pathological stage I between VATS group and OT group, but significant differences were found in the number of station of LND and the number of LND in pathological stage II and stage IIIA between the 2 groups. Compared with those who underwent OT wedge resection （n = 72）, the patients who underwent VATS wedge resection （n = 108） had shorter operative time, chest tube duration and hospital LOS, and there were no significant differences in morbidity of the complications and mortality between the 2 groups. CONCLUSION VATS lobectomy can be performed for patients with clinical stage I lung cancer （with tumor diameter smaller than 5 cm, without hilar and mediastinal lymph node enlargement）. VATS lobectomy is superior to OT lobectomy in short-term outcomes, although further studies exploring long-term outcomes through longer follow-up is needed to determine the oncologic equivalency between the VATS and th

关键词： thoracic surgery video-assisted lung neoplasms thoracotomy.

The Application of Specific Nursing in Perioperative Patients of thoracic surgery and Postoperative Recovery and Improvement of Patients’ Negative Emotions

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Journal of Biosciences and Medicines 2021年第6期9卷 169-181页

作者： Fen Xue Junrong Ding Min Lu Yanjun Mao Special Needs Ward I Shanghai Pulmonary Hospital Shanghai China Department of thoracic surgery Shanghai Pulmonary Hospital Shanghai China Nursing Department Shanghai Pulmonary Hospital Shanghai China

Objective: To study the application of specific nursing in perioperative patients of thoracic surgery and postoperative recovery and improvement of patients’ negative emotions. Patients and Methods: A total of 88 patients in the thoracic surgery operating room of our hospital were selected and divided into group A (specific nursing, n = 44) and group B (routine nursing, n = 44). The anxiety and depression status of the two groups were assessed by the Self-rating Anxiety Scale (SAS) and the Self-rating Depression Scale (SDS). The relevant respiratory parameters after surgery, including total lung capacity, maximum respiration flow-rate, tidal volume, and vital capacity were observed. The extubation time, ICU hospitalization time, and VAS scores of postoperative pain were compared, with a score of 10 being full. The higher the score, the higher the pain. The in-cidence of postoperative wound infection, pulmonary infection, respiratory tract infection and the satisfaction with the operation were compared. Sf-36 scale was used to score the physical function, life function, psychological function and quality of life of the patients in the two groups. Results: The surgical effect of group A was significantly higher than that of group B (all p Conclusion: Specific nursing has higher application value than routine nursing, which is worth further promotion in clinic.

关键词： Specific Nursing thoracic surgery Postoperative Recovery Negative Emotions

Perspectives on early-stage lung cancer identification and challenges to thoracic surgery

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Chronic Diseases and Translational Medicine 2022年第2期8卷 79-82页

作者： Xiao Li Kezhong Chen Fan Yang Jun Wang Department of thoracic surgery Peking University People's HospitalBeijing100044China

Lung cancer is one of the leading causes of cancer-related death worldwide with the long-term survival rate for stage I cancers treated with surgery reaching over 80%,but rapidly reducing as disease develops with stage III cancer patients presenting with a long-term survival rate of just 20%.Altliough surgery remains die most effective strategy for treating early stage lung cancers,screening and early diagnosis remain critical for improving prognosis in lung *** addition to advancements in surgical techniques,die rapid development of artificial intelligence(AI),liquid biopsy,and other technologies in recent years has led to new breakthroughs in the diagnosis of this *** application of neoadjuvant therapies using immune checkpoint inhibitors have also shown promise for improved efficacy in the treatment of early stage lung *** editorial was designed to summarize the recent progress around the screening and diagnosis of early stage lung cancers and the challenges associated with various surgical strategies for treating these patients.

关键词： early-stage lung cancer progress thoracic surgery

Management strategies in a thoracic surgery ward during COVID-19 pandemic: Experience from West China Hospital

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World Journal of Virology 2020年第4期9卷 47-53页

作者： Lin Lin Ling-Li Niu E Zheng Yong Yuan Ning Ning Mei Yang West China School of Nursing Sichuan UniversityChengdu 610041Sichuan ProvinceChina Department of thoracic surgery West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Orthopedic surgery West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina

The coronavirus disease 2019 was first reported in Wuhan in December 2019 and then spread rapidly throughout the *** March 11,2020,the World Health Organization declared coronavirus disease 2019 a *** response to the pandemic,the management division of West China Hospital oversaw the implementation of hospital-wide emergency *** accordance with these measures,the hospital's thoracic surgery ward implemented a new management system by reformulating staff training plans,patient admission procedures,and other systems for managing the ward and protecting perioperative ***,the ward was successful in restoring normal working order,protecting all staff from occupational exposures,and ensuring the safety of inpatients and their families.

关键词： COVID-19 thoracic surgery thoracic surgery ward management SARSCoV-2 Epidemic prevention and control Nosocomial infection

The Application of Specific Nursing in Perioperative Patients of thoracic surgery and Postoperative Recovery and Improvement of Patients’ Negative Emotions

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The Application of Specific Nursing in Perioperative Patient...

Quality of Sleep at the Ward after Cardiothoracic surgery

作者： Fen Xue Junrong Ding Min Lu Yanjun Mao Special Needs Ward I Shanghai Pulmonary Hospital Department of thoracic surgery Shanghai Pulmonary Hospital Nursing Department Shanghai Pulmonary Hospital

Objective: To study the application of specific nursing in perioperative patients of thoracic surgery and postoperative recovery and improvement of patients’ negative emotions. Patients and Methods: A total of 88 patients in the thoracic surgery operating room of our hospital were selected and divided into group A（specific nursing, n = 44） and group B（routine nursing, n = 44）.The anxiety and depression status of the two groups were assessed by the Self-rating Anxiety Scale（SAS） and the Self-rating Depression Scale（SDS）.The relevant respiratory parameters after surgery, including total lung capacity, maximum respiration flow-rate, tidal volume, and vital capacity were observed. The extubation time, ICU hospitalization time, and VAS scores of postoperative pain were compared, with a score of 10 being full. The higher the score, the higher the pain. The incidence of postoperative wound infection, pulmonary infection, respiratory tract infection and the satisfaction with the operation were compared. Sf-36 scale was used to score the physical function, life function, psychological function and quality of life of the patients in the two groups. Results: The surgical effect of group A was significantly higher than that of group B（all p ＜ 0.05）. The total lung capacity, maximum respiration flow-rate, tidal volume and vital capacity of group A were significantly higher than those of group B（all p ＜ 0.05）. The extubation time and hospitalization time of group A were significantly higher than those of group B（all p ＜ 0.05）. VAS score of group A was significantly lower than that of group B（all p ＜ 0.05）. The infection rate of group A was significantly lower than that in group B（all p ＜ 0.05）. Conclusion: Specific nursing has higher application value than routine nursing, which is worth further promotion in clinic.

关键词： Specific Nursing thoracic surgery Postoperative Recovery Negative Emotions

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Open Journal of Nursing 2015年第6期5卷 529-537页

作者： Jozefine Propper Richard van Valen Ron Tvan Domburg Maaike Brunott Ad J.J.C.Bogers Department of Cardio-thoracic surgery ThoraxcenterErasmus Medical CenterRotterdamThe Netherlands Department of Cardiology ThoraxcenterErasmus Medical CenterRotterdamThe Netherlands

Objective: Sleeping problems are among the issues most mentioned by patients after cardiothoracic surgery. These problems can have a negative effect on duration of the hospital stay and recovery. In the ward of our cardiothoracic surgery department, a study was initiated to assess the quality of sleep after cardiothoracic surgery. The primary objective was to investigate the effect of cardiothoracic surgery on the quality of sleep. The secondary objective was to investigate the quality of sleep. Correlations with perioperative factors and related issues such as the type of surgery and medication were sought. Methods: A consecutive prospective cohort study was initiated (N = 72). The study used validated questionnaires to assess sleep: the Pittsburgh Sleep Quality Index (PSQI), the Epworth Sleepiness Scale (ESS), the Verran Snyder-Halpern Sleep Scale (VSH) and the Factors Influencing Sleep Quality (FISQ). Results: The PSQI showed that the quality of sleep one month after surgery was inferior to the quality of sleep before surgery (p-value: 0.03). The efficiency of sleep (time spent in bed) was higher after surgery then before surgery (p-value: 0.01). The VSH showed increased impaired sleep on the third night after surgery. The most disruptive factors were not being comfortable in a hospital bed, pain and the noise of medical devices. Conclusions: The quality of sleep after cardiothoracic surgery is worse when compared with the preoperative situation. The chief influencing factors are discomfort in bed, pain and disturbance from medical devices. The use of pain medication does not improve the quality of sleep.

关键词： Cardiac surgery thoracic surgery Sleep Sleep Deprivation Factors Influencing Sleep Quality (FISQ)

Perioperative massive cerebral stroke in thoracic patients:Report of three cases

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World Journal of Clinical Cases 2021年第13期9卷 3170-3176页

作者： Min-Yu Jian Fa Liang Hai-Yang Liu Ru-Quan Han Department of Anesthesiology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China

BACKGROUNDPerioperative stroke is a rare but devastating complication. The risk factors formassive cerebral stroke in surgical patients include older age, male sex, priorcerebrovascular disease, hypertension, renal failure, smoking, diabetes mellitus,and atrial *** SUMMARYWe describe two cases of perioperative massive cerebral stroke following thoracicsurgery and one case following bronchoscopy. Neurologic symptoms, includingchanges in mental status and hemiplegia, occurred within 10 h after surgery in thethree patients. All three patients died after the *** massive cerebral stroke may be more likely to occur in thoracicsurgical patients if there are pre-existing factors including previous stroke,hypotension, and hypoxemia. Sufficient pain control after surgery and timelyneurology consultation and management are helpful for the diagnosis and controlof stroke in high-risk patients.

关键词： Perioperative Massive cerebral stroke thoracic surgery Anesthesia Literature review Case report

Contralateral hemopneumothorax after penetrating thoracic trauma:A case report

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World Journal of Clinical Cases 2021年第15期9卷 3773-3778页

作者： Mehlikaİşcan thoracic surgery Department Gebze Fatih State HospitalKocaeli 41400GebzeTurkey

BACKGROUND Trauma is the leading cause of death in young adults up to the age of 45 *** is a frequent consequence of penetrating thoracic trauma,and is usually associated with pneumothorax and *** arterial bleeding or intrathoracic hemorrhage occurs after penetrating thoracic trauma,and uncontrolled bleeding is the main cause of *** SUMMARY In this case report,a patient who developed a right hemopneumothorax after penetrating thoracic trauma was examined.A 19-year-old male patient,who was brought to the emergency room with a penetrating stab injury to the posterior of the left hemithorax,was diagnosed with a right hemopneumothorax after physical examination and thoracic *** tube thoracostomy was performed as the initial *** control was achieved with right posterolateral thoracotomy in the patient,who developed massive hemorrhage after 1 h and hemodynamic *** patient recovered and was discharged on the fourth postoperative *** Contralateral hemopneumothorax that accounts for 30%of thoracic traumas and can be encountered in penetrating thoracic traumas requiring major surgery in 15-30%of cases was emphasized and the contralateral development mechanism was addressed.

关键词： Chest tube Contralateral hemopneumothorax Penetrating thoracic trauma Thoracotomy thoracic surgery Tube thoracostomy Case report