检索结果-南通市图书馆

the feeding behavior of cross-intestine parabiotic rats are modulated by brain histamine

中国病理生理杂志 2001年第8期 77-77页

作者： H.Noguchi H.Koopmans H Tanaka T.Fukagawa K.Goto K.Fukagawa H.Yoshimatsu T.Sakata Department of Internal Medicine Oita Medical University Hasoma Oita 879-5593 Japan

To clarify the mechanism in which signals to regulate food intake are transmitted from the gastro-intestinal system to the brain, we analyzed changes in hypothalamic neuronal histamine using cross-intestine parabiotic rats. Pairs of weight matched Lewis rats were sewn together in such a way as to form a common abdominal cavity. The small intestines of rats were transected and reconnected so that food eaten by one rat passed through a segment of its partner's intestine before returning to the intestine of the first rat. Concentrations of neuronal histamine were measured in microdissected hypothalami using radioimmnoassay. Sustained alteration of food intake were observed in both rats, one rat eating an average of 2.2 times (SE 0.15) as much as the other, without development of any significant difference in body weight after seven weeks. We found significant increase in hypothalamic neuronal histamine concentrations in the arcuate and tublomamelary nuclei of the hypophagic *** results are supportive of the theory that histamine acts in response to signals from the gut to regulate food intake.

关键词： the feeding behavior of cross-intestine parabiotic rats are modulated by brain histamine

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：