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abo blood group is a predictor of survival in patients with laryngeal cancer

Chinese Journal of Cancer 2016年第12期35卷 706-712页

作者： Ting Jin Pei-Jing Li Xiao-Zhong Chen Wei-Han Hu Key Laboratory of Radiation Oncology in Zhejiang Province Hang-zhou 310022ZhejiangP.R.China. Department of Radiation Oncology Zhejiang Cancer Hospital38 Guang Ji RoadHangzhou 310022ZhejiangP.R.China. State Key Laboratory of Oncology in South China Department of Radiation OncologyCollaborative Innovation Center of Cancer MedicineSun Yat-sen University Cancer CenterNo.651 Dongfeng Road EastGuang-zhou 510060GuangdongP.R.China.

Background: Whether the abo blood group is associated with the survival of patients with laryngeal cancer remains unknown. The purpose of this study was to investigate the association between the abo blood group and clinico?pathologic characteristics of patients with laryngeal cancer and assess whether the abo blood group was associated with ***: We analyzed the records of 1260 patients with laryngeal cancer who underwent curative treatment at Sun Yat?sen University Cancer Center between January 1993 and December 2009. The Chi?square test was used to assess the relationship between the abo blood group and clinicopathologic characteristics. The Kaplan–Meier method was used to estimate 3?, 5?, and 10?year overall survival(OS) rates. The Cox proportional hazards model was used in univariate and multivariate analyses of ***: No signiicant association was found between the abo blood group and clinicopathologic characteristics except for primary tumor site. The median OS for patients with blood groups A, B, AB, and O were 87.0, 80.0, 90.0, and 72.5 months, respectively. The 3?, 5?, and 10?year OS rates were 82.4%, 76.0%, and 67.5% for patients with blood group A; 77.4%, 69.8%, and 58.4% for patients with blood group B; 82.2%, 73.1%, and 65.6% for patients with blood group AB; and 71.7%, 66.4%, and 55.5% for patients with blood group O, respectively. Univariate and multivariate analyses showed that the abo blood group had signiicant efects on prognosis in patients with laryngeal ***: the abo blood group is associated with survival in patients with laryngeal cancer. Patients with blood group O had signiicantly shorter OS than patients with other abo blood groups.

关键词： the abo blood group Laryngeal cancer Prognosis Survival

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