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Surveillance of dengue and chikungunya infection in Dong Thap,Vietnam:A 13-month study

Asian Pacific Journal of Tropical Medicine 2016年第1期9卷 36-40页

作者： Pham Thi Kim Lien Laurence Briant Truong Ba Tang Bui Minh Trang Laurent Gavotte Emmanuel Comillot Vu Trong Duoc Tran Nhu Duong Roger Frutos Phan Thi Nga National Institute of Hygiene and Epidemiology University of Montpellier Department of Biology Dong Thap General Hospital Cirad TA-A17/GCampus International de Raillarguet

Objective:To establish a surveillance in Dong Thap,at the border with Cambodia by assessing the presence of DHNV serotypes and CHIKV among patients hospitalized at Dong Thap general ***:Cross-sectional descriptive analysis was conducted on a cohort of 131 patients hospitalized with acute fever and symptoms compatible with dengue or *** study was conducted from January 2012 to February *** full clinical picture was established as well as serological and molecular *** analysis was sequentially performed on blood samples collected on admission and an average of seven days after *** detection of IgM antibody to DENV was performed by IgM capture ELTSA and the detection of DENV and CHIKV RNA was done by reverse-transcription multiplex ***:101 patients out of 131(77%) were confirmed with *** four dengue serotypes were detected with a predominance of DENV2 and *** chikungunya infection was detected although reported in neighboring Cambodia.A differential efficiency of serological dengue detection was *** was 29%upon admission and 53%after seven days on the same patients.30 patients out of 131(23%) were negative with both DENV and ***:Dengue is at risk of being underestimated and chikungunya is not systematically *** in detection and surveillance procedures are therefore discussed to increase efficiency of dengue detection and continue the monitoring the emergence of CHIKV in Dong Thap province and in Vietnam.

关键词： Dengue Chikungunya Arbovirus Dong thapvietnam

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