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Effectiveness of a Single High Dose of Platelet-Rich Plasma (PRP) Injection Over Corticosteroid and Hyaluronic Acid Injections on Osteoarthritis, Chronic Tendinitis and tennis elbow Treatment

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Open Journal of Regenerative Medicine 2022年第2期11卷 41-53页

作者： Charbel Khalil Diana Chaker Albert Azar Elie El Kayem Rawad Salameh Mohamad Dar-Yahya Fadi Nader Alain Chebly Kamil Samaha Ahmad Ibrahim Reviva Stem Cell Platform for Research and Applications Center Bsalim Lebanon Middle East Institute of Health University Hospital Bsalim Lebanon Bone Marrow Transplant Unit Burjeel Medical City Abu Dhabi UAE Stem Cell Institute Faculty of Medical Sciences Lebanese University Beirut Lebanon NSERM National Institute of Health and Medical Research Paris XI Paris France Faculty of Medicine Lebanese American University Beirut Lebanon Lebanese University Faculty of Medicine Beirut Lebanon Medical Genetics Unit (UGM) Faculty of Medicine Saint Joseph University Beirut Lebanon Higher Institute of Public Health Saint Joseph University Beirut Lebanon

Background: Corticosteroid, hyaluronic acid (HA) injections and Anti-inflammatory agents are considered as non-invasive treatments for knee osteoarthritis (OA), Chronic Tendinitis (CT) and tennis elbow (TE) that are supposed to provide symptomatic relief and to help surgical delay intervention. Platelet rich plasma (PRP) is a biological component shown to be beneficial for different orthopedic dysfunctionalities treatment. The presence of GFs in PRPs such as transforming growth factor-β, insulin-like growth factor 1co-stimulate the mesenchymal stem cells and fibroblasts secretions and promotes the fibrin matrix formation which effectively drive the healing process, induces regenerative response and lead to the damage structure repair in orthopedics trauma. Methods: Three groups of a total of 30 patients presenting OA, CT and TE diagnosis, non-responding to corticosteroid, HA and non-steroid anti-inflammatory treatments were randomized to undergo one intra-articular injections of single high dose of PRP. The efficacy of Intra-articular PRP Injections was evaluated before the injection and one month after. The efficiency assessment score was based on [1] Knee injury and Osteoarthritis Outcome Score, [2] Physical Function Short Form (KOOS-PS) Arabic (KSA) version LK 1.0, [3] HOOS-Physical Function Short form (HOOS-PS), and [4] Macdermid patient-rated tennis elbow. Results: A significant reduction of pain and a marked improvement in movements was observed in the 3 patient’s groups, PRP-injected patients showed significantly higher values compared with baseline: (p < 0.005 vs baseline), improve functional status and reduce clearly the articular dysfunctions over the time. In our study, single High dose injection of PRP provided an overall superior clinical improvement compared with HA and corticosteroid treatments over the time and the different follow-up checkpoints of the study.

关键词： Platelet Rich Plasma (PRP) Osteoarthritis Chronic Tendinitis tennis elbow Corticosteroid Hyaluronic Acid Non-Steroid Anti-Inflammatory

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The Effect of Deep Friction Massage versus Stretching of Wrist Extensor Muscles in the Treatment of Patients with tennis elbow

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Open Journal of Therapy and Rehabilitation 2016年第1期4卷 48-54页

作者： Sahar Mahmoud Hassan Ashraf Ramadan Hafez Hamada Eid Seif Shaji John Kachanathu Cairo University Hospital Cairo University Egypt Faculty of Physical Therapy Deraya University Alminya Algadida Egypt Collage of Applied Medical Sciences King Saud University Riyadh Saudi Arabia

Overuse injuries of the elbow and forearm are very common in athletes. This study was conducted to evaluate the effect of muscle stretching and deep friction massage with using wrist joint support during management of tennis elbow. This study included forty patients with tennis elbow divided into two equal groups: the first group with a mean age 38.1 ± 0.294 followed a physical therapy program in form of deep friction massage on the proximal attachment of wrist extensor muscles, the second group with a mean age 37.6 ± 0.253, submitted to stretching exercises of wrist extensors. Both of groups submitted to ultrasonic therapy with wrist splint during treatment period, three sessions per week for six weeks. Outcome measures were universal goniometer, visual analogue scale, and squeezing sphygmomanometer. The results showed that there was a significant improvement in ROM of wrist flexion and wrist extension, and handgrip in second group and it was more than in the first group while no significant difference in pain. This study showed that stretching exercise is more beneficial in the management of patients with tennis elbow.

关键词： tennis elbow Stretching Exercises of Wrist Extensors Ultrasonic Therapy and Deep Friction Massage Splinting

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DEVELOPMENT OF A QUESTIONNAIRE TO FACILITATE CHINESE MEDICINE PATTERN DIFFERENTIATION OF LATERAL elbow PAIN(tennis elbow):RESULTS FROM A DELPHI PROCESS

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Journal of Integrative Medicine 2014年第3期 297-297页

作者： Shi-Ping Zhang Wing-Fai Yeung Marcus Gadau Zhao-Xiang Bian School of Chinese Medicine Hong Kong Baptist University Department of Psychiatry University of Hong Kong

Background: Acupuncture is a possible alternative treatment method for lateral elbow pain(LEP).Individualized acupuncture treatment has been practiced for pain therapy; however, studies on the underlying rational for individualized acupuncture treatment are ***: To develop a questionnaire using the Delphi process that can assist acupuncturists to assess the underlying traditional Chinese medicine(TCM) pattern of ***: First, a multi-disciplinary research team was formed to conduct the Delphi survey.A provisional version of the questionnaire was developed by(1) comprehensive literature search on acupuncture for LEP as well as symptoms and TCM patterns associated with LEP;(2) extensive literature review from text books on TCM patterns;(3) meetings of a representative of the research team with specialized acupuncturists to consult expert *** of the Delphi survey consisted of experts with substantial clinical and research experience in acupuncture for LEP.A total of 33 international and national experts were invited by *** Delphi survey was terminated after two *** each round consensus was defined by content validity index(CVI) of ≥ 0.51(representing a 51% level of consensus).Results: Consensus was found on 72 of the 74 symptoms that could be indicative for a specific TCM pattern of *** was achieved from all 25 panelists who responded to the second round on all four TCM patterns that could underlie LEP, namely, Invasion of Wind-Cold Dampness, Retention of Damp-Heat, Deficiency of Qi and Blood and Stagnation of Qi and Blood.A list of symptoms that indicate one of the four TCM patterns and a list of preferred treatment modalities for each pattern were also generated via CVI of ≥ 0.51 during the Delphi ***: The current version of the Delphi-based questionnaire appeared to have considerable face and content *** reliability and validity are currently being tested.

关键词： Delphi RESULTS FROM A DELPHI PROCESS tennis elbow DEVELOPMENT OF A QUESTIONNAIRE TO FACILITATE CHINESE MEDICINE PATTERN DIFFERENTIATION OF LATERAL elbow PAIN

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Lateral epicondylitis:New trends and challenges in treatment

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World Journal of Orthopedics 2022年第4期13卷 354-364页

作者： Vesselin Karabinov Georgi P Georgiev Clinic of Neurology National Cardiology HospitalSofia 1000Bulgaria Department of Orthopedics and Traumatology University Hospital Queen Giovanna-ISULMedical University of SofiaSofia 1527Bulgaria

Lateral epicondylitis(LE)is a chronic aseptic inflammatory condition caused by repetitive microtrauma and excessive overload of the extensor carpi radialis brevis *** is the most common cause of musculoskeletal pain syndrome in the elbow,inducing significant pain and limitation of the function of the upper *** affects approximately 1-3%of the population and is frequently seen in racquet sports and sports associated with functional overload of the elbow,such as tennis,squash,gymnastics,acrobatics,fitness,and weight ***,artists,musicians,electricians,mechanics,and other professions requiring frequent repetitive movements in the elbow and wrists are also *** is a leading causation for absence from work and lower sport results in *** treatment includes a variety of conservative measures,but if those fail,surgery is *** review summarizes the knowledge about this disease,focusing on risk factors,expected course,prognosis,and conservative and surgical treatment approaches.

关键词： Diagnosis Lateral epicondylitis tennis elbow Treatment Review

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Diagnostic confidence of sonoelastography as adjunct to greyscale ultrasonography in lateral elbow tendinopathy

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Chinese Medical Journal 2014年第17期127卷 3110-3115页

作者： Park Giyoung Kwon Dongrak Park Junghyun Department of Rehabilitation Medicine Catholic University of Daegu School of Medicine Daegu Korea Department of Rehabilitation Medicine Gangnam Severance Hospital Rehabilitation Institute of Neuromuscular Disease Yonsei University College of Medicine Seoul Korea

Background Conventional ultrasonography or magnetic resonance （MR） imaging is commonly performed to obtain information about the severity of the disease,location of the injury,and differential *** aim of this research was to investigate the diagnostic confidence of sonoelastography as an adjunct to greyscale ultrasonography in lateral elbow *** A single experienced physiatrist performed greyscale ultrasonography and sonoelastography in 28 patients （9 men,19 women; mean age,48.5 years; age range,36-67 years） with unilateral symptoms of lateral elbow tendinopathy; the asymptomatic elbows were used as *** images were described as normal,tendinosis,partialthickness tear,and full-thickness *** images of the common extensor tendon were analyzed qualitatively （scoring of the elastic spectrum） and quantitatively （based on a color histogram）.Results Both the imaging methods had high sensitivity,specificity,and accuracy for diagnosing lateral elbow *** the clinical diagnosis of lateral elbow tendinopathy,sonoelastography showed significantly higher diagnostic accuracy （96.4％） than ultrasonography （89.5％,P ＜0.01）.Quantitative analysis showed objective interpretation of the sonoelastographic images that revealed greater intensity of green and blue pixels in symptomatic elbows （P ＜0.01）.Conclusion Sonoelastography increases diagnostic confidence in tennis elbow pathology over greyscale ultrasonography alone and may be an additional powerful diagnostic tool in cases of lateral elbow tendinopathy with inconclusive greyscale ultrasonographic findings.

关键词： sonoelastography ultrasonography tennis elbow tendons

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