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Iatrogenic scleroderma renal crisis:A case report and mini literature review for renal crisis

Discussion of Clinical Cases 2021年第3期8卷 4-8页

作者： Gülsah Boz Samet Karahan Nurdan Yüksek Kayseri City Education and Research Hospital Department of Internal MedicineDivision of NephrologyKayseriTurkey Kayseri City Education and Research Hospital Department of Internal MedicineDivision of RheumatologyKayseriTurkey Kayseri City Education and Research Hospital Department of Internal MedicineKayseriTurkey

Background:systemic sclerosis is a connective tissue disease characterized by fibrosis of the skin and organs,marked changes in microvascular structure,cellular and humoral immune *** involvement is more frequent and mainly characterized by moderate proteinuria,elevated serum creatinine levels,and *** most common kidney involvement in SSc is scleroderma renal crisis(SRC)that is fatal without prompt *** report:A 52-year-old Caucasian male with known diffuse cutaneous systemic sclerosis was hospitalized with communityacquired *** the fifth day after appropriate antibiotic therapy and 60 mg/day methylprednisolone,decreased urine output,arterial hypertension,decreased renal function and pulmonary edema *** patient was diagnosed with a scleroderma renal *** hemodialysis was applied to the patient,and captopril 6×25 mg/day and nifedipine 2*60 mg/day treatment were *** received a routine hemodialysis program for about three *** hemodialysis program was terminated when the patient’s urine quality and quantity ***:SRC,characterized by malignant hypertension,azotemia,microangiopathic hemolytic anemia,and kidney failure,is one of the most important complications of systemic sclerosis with a poor prognosis without prompt *** use is one of the important risk factors that precipitate SRC *** angiotensin-converting enzyme inhibitors,survival increased after SRC,the need for dialysis decreased,and usually allowed the discontinuation of dialysis treatment within about 6-18 *** of SRC in the presence of the above-mentioned findings in patients with a diagnosis or suspected systemic sclerosis can be considered the most important treatment step.

关键词： Scleroderma systemic sclerosis Scleroderma renal crisis systemic sclerosis-associated thrombotic microangiopathy

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