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Optical force-induced nonlinearity and self-guiding of light in human red blood cell suspensions

Light(Science & Applications) 2019年第1期8卷 927-935页

作者： Rekha Gautam Yinxiao Xiang Josh Lamstein Yi Liang Anna Bezryadina Guo Liang Tobias Hansson Benjamin Wetzel Daryl Preece Adam White Matthew Silverman Susan Kazarian Jingjun Xu Roberto Morandotti Zhigang Chen Department of Physics and Astronomy San Francisco State UniversitySan FranciscoCA 94132USA Department of Biomedical Engineering Vanderbilt UniversityNashvilleTN 37240USA MOE Key Lab of Weak-Light Nonlinear Photonics TEDA Applied Physics Institute and School of PhysicsNankai UniversityTianjin 300457China Guangxi Key Lab for Relativistic Astrophysics Guangxi Colleges and Universities Key Lab of Novel Energy Materials and Related TechnologySchool of Physical Science and TechnologyGuangxi UniversityNanningGuangxi 530004China Department of Physics and Astronomy California State University NorthridgeNorthridgeCA 91330USA Institut National de la Recherche Scientifique Universite du QuebecVarennesQC J3X 1S2Canada Department of Physics Chemistry and BiologyLinkoping UniversityLinkoping SE-58183Sweden School of Mathematical and Physical Sciences University of SussexSussex HouseFalmerBrighton BN19RHUK Department of Biomedical Engineering University of California IrvineIrvineCAUSA Clinical Laboratory Science Program San Francisco State UniversitySan FranciscoCA 94132USA Institute of Fundamental and Frontier Sciences University of Electronic Science and Tech.of ChinaChengdu 610054China ITMO University Saint Petersburg 197101Russia

Osmotic conditions play an important role in the cell properties of human red blood cells(RBCs),which are crucial for the pathological analysis of some blood diseases such as *** the past decades,numerous efforts have mainly focused on the study of the RBC biomechanical properties that arise from the unique deformability of ***,we demonstrate nonlinear optical effects from human RBCs suspended in different osmotic ***,we observe self-trapping and scattering-resistant nonlinear propagation of a laser beam through RBC suspensions under all three osmotic conditions,where the strength of the optical nonlinearity increases with osmotic pressure on the *** tunable nonlinearity is attributed to optical forces,particularly the forward-scattering and gradient ***,in aged blood samples(with lysed cells),a notably different nonlinear behavior is observed due to the presence of free *** use a theoretical model with an optical force-mediated nonlocal nonlinearity to explain the experimental *** work on light self-guiding through scattering biosoft-matter may introduce new photonic tools for noninvasive biomedical imaging and medical diagnosis.

关键词： nonlinearity suspensions nonlinear

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The stress-microstructure relationship in an evolving mixing layer of fiber suspensions

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Acta Mechanica Sinica 2005年第1期21卷 16-23页

作者： JianzhongLin YelongWang ZhaoshengYu DepartmentofMechanics theStateKeyLaboratoryofFluidPowerTransmissionandControlZhejiangUniversityHangzhou310027China DepartmentofMechanicalandMechatronicEngineering UniversityofSydneyNSW2006Australia

The equations for fiber suspensions in an evolving mixing layer were solved by the spectral method, and the trajectory and orientation of fibers were calculated based on the slender body theory. The calculated spatial and orientation distributions of fibers are consistent with the experimental ones that were performed in this paper. The relationship between the microstructure of fibers and additional stress was examined. The results show that the spatial and orientation distributions of fibers are heterogeneous because of the influence of coherent vortices in the flow, which leads to the heterogeneity of the additional stress. The degree of heterogeneity increases with the increasing of St number and fiber aspect ratio. The fibers in the flow make the momentum loss thickness of the mixing layer thicker and accelerate the vorticity dispersion.

关键词： Fiber suspensions Stress Microstructure Mixing layer

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A New Method of Simulating Fiber suspensions and Applications to Channel Flows

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Chinese Physics Letters 2012年第6期29卷 189-192页

作者： YANG Wei ZHOU Kun Department of Mechanics Zhejiang UniversityHangzhou 310027 Clean Combustion Research Center King Abudullah University of Science and TechnologyThuwalSaudi Arabia

A successive iteration method is proposed to numerically simulate fiber *** computational field is discretized with the collocated finite volume method,and an ergodic hypothesis is adopted to gready accelerate the solution to the Fokker-Planck *** method is employed in channel flows with different fiber volume fractions and aspect ratios,and its effectiveness is *** numerical results show that the existence of fibers significantly changes the pressure distribution,and the fiber aspect ratio has a greater effect on the velocity profile than on the volume *** the center of the channel,the velocity increases along the streamwise direction,while the velocity near the wall decreases *** uncoupling and coupling solutions of the additional stress of the fiber suspensions are quite different.

关键词： equation suspensions iteration

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Dielectric Polarization of Electrorheological suspensions

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Chinese Physics Letters 1995年第9期12卷 573-576页

作者： HAO Tian XU Yuanze CHEN Yihong XU Mao Institute of Chemistry Academia SinicaBeijing 100080

The relation between electrorheological(ER)effect and dielectric properties of Polymer-based and inorganic-based suspensions were *** is found that ER effect is determined not only by the dielectric constant of the suspended particles,but also by the dielectric loss,which provides a criterion whether suspension exhibits ER *** wagner model,which describes the interfacial polarization occurring in multiphase systems,was introduced to predict the dielectric behaviours of ER suspensions.A good agreement is found between experiments and theoretical *** conductivity of the dispersed particles,the working temperature range and working frequency range of ER suspension can be optimized with Wagner *** other ER phenomena such as the effect of water content were also explained by using this model.

关键词： dielectric suspensions effect

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Effect of surface treatment on rheological behaviors of glass bead/hydroxyl terminated polybutadiene suspensions

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Journal of Central South University 2008年第S1期15卷 158-162页

作者：崔伟赵瑾朝王承哲周兴平解孝林 School of Chemistry and Chemical Engineering Huazhong University of Science and Technology Hubei Key Laboratory of Materials Chemistry and Service Failure Huazhong University of Science and Technology

Surface treatment of glass bead(GB) was carried out by using γ-glycidoxypropyltrimethoxy silane(GPTES) and γ-methacryloxypropyltrimethoxy silane(MPTMS) as coupling agents,*** steady viscosity and yield stress of the GB/hydroxyl terminated polybutadiene(HTPB) suspensions were determined by Brookfield R/S *** effect of surface treatment on the viscosity and yield stress of GB/HTPB suspension was *** results indicate that the viscosity of the pristine GB/HTPB suspension increases with increasing GB,and the relationship between its viscosity and volume fraction of GB depends on the shear *** modification of GB by MPTMS changes the viscosity of the MPTMS@GB/HTPB suspension,and its viscosity is the minimum at the MPTMS dosage of 0.3 g per 1 g ***,the modification of GB by MPTMS increases the yield stress of the GB/HTPB suspension,and its yield stress is the maximum at the MPTMS dosage of 0.1 g per 1 g *** GPTES modified GB/HTPB suspension behaves lower viscosity and weaker shear thinning than the MPTMS modified GB/HTPB suspension within the range of experimental shear rate.

关键词： glass bead suspensions coupling agent steady shear viscosity yield stress

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Dynamics simulation of electrorheological suspensions in poiseuille flow field

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Journal of Central South University 2008年第S1期15卷 234-238页

作者：朱石沙罗成周杰陈娜 College of Mechanical Engineer Xiangtan University Changshu Institute of Technology

Based on a modified Maxwell-Wagner model,molecular dynamics is carried out to simulate the structural changes of ER(electrorheological) suspensions in a poiseuille flow *** simulation results show that the flow assists in the collection of particles at the electrodes under a low pressure gradient,and the negative ER effect will show under a high pressure *** analyzing the relationship curves of the shear stress and the pressure gradient in different relaxation time,it is found that for the same kind of ER suspensions materials,there is an optimal dielectric relaxation frequency.

关键词： electrorheological suspensions molecular dynamics pressure gradient value relaxation time.

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Development and validation of RP-HPLC method for determination of acetazolamide, furosemide and phenytoin extemporaneous suspensions

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Asian Journal of Pharmaceutical Sciences 2016年第1期11卷 138-139页

作者： Warisada Sila-on Salinee Na-Ranong Sirilak Rakrod Sarote Ornlaor Zongporn Joungmunkong Ubon Ratchathani University Ubon Ratchathani 34190Thailand Division of Pharmacy Sappasit Prasong HospitalUbon RatchathaniThailand

The development of the extemporaneous preparations allows physicians to adjust the dose for pediatric patients and provides for a more convenient dosage vehicle for those patients with difficulty swallowing tablets[1].As such,the production unit of pharmacy division,Sappasit Prasong Hospital,Ubon Ratchathani province,prepared the extemporaneous formulations such as Acetazolamide(AM),Furosemide(FM)and Phenytoin(PT)powder for *** extemporaneous suspensions of 10 mg/mL AM,2 mg/mL FM and 10 mg/mL PT were prepared from 250 mg Diamox?,40 mg Lasix?and 50 mg Dilantin?tablets,respectively and diluted with syrup vehicle.

关键词： Development and validation of RPHPLC method Extemporaneous suspensions

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Biophotonic rogue waves in red blood cell suspensions

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Photonics Research 2023年第11期11卷 1838-1846页

作者： YU-XUAN REN JOSHUA LAMSTEIN CHENSONG ZHANG CLAUDIO CONTI DEMETRIOS NCHRISTODOULIDES ZHIGANG CHEN Institute for Translational Brain Research MOE Frontiers Center for Brain ScienceFudan UniversityShanghai 200032China Department of Physics and Astronomy San Francisco State UniversitySan FranciscoCalifornia 94132USA Center for Systems and Therapeutics Gladstone InstitutesSan FranciscoCalifornia 94158USA Division of CryoEM and Bioimaging Stanford Synchrotron Radiation LightsourceSLAC National Accelerator LaboratoryMenlo ParkCalifornia 94025USA Department of Physics University SapienzaI-00185 RomaItaly Department of Electrical Engineering University of Southern CaliforniaLos AngelesCalifornia 90089USA TEDA Applied Physics Institute and School of Physics Nankai UniversityTianjin 300457China

Rogue waves are ubiquitous in nature,appearing in a variety of physical systems ranging from acoustics,microwave cavities,optical fibers,and resonators to plasmas,superfluids,and Bose–Einstein *** nonlinear solitary waves,rogue waves are extreme events that can occur even without nonlinearity by,for example,spontaneous synchronization of waves with different spatial frequencies in a linear ***,we report the observation of rogue-wave-like events in human red blood cell(RBC)suspensions under weak light illumination,characterized by an abnormal L-shaped probability *** biophotonic extreme events arise mostly due to the constructive interference of Mie-scattered waves from the suspended RBCs,whose biconcave shape and mutable orientation give rise to a time-dependent random phase modulation to an incident laser *** numerically simulate the beam propagation through the colloidal suspensions with added disorder in both spatial and temporal domains to mimic random scattering due to Brownian *** addition,at high power levels,nonlinear beam self-focusing is also observed,leading to a dual-exponential probability distribution associated with the formation of multiple soliton-like *** rogue wave events should also exist in environments with cells of other species such as swimming bacteria,and understanding of their underlying physics may lead to unexpected biophotonic applications.

关键词： suspensions extreme soliton

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Microchip Electrode Development for Traveling wave Dielectrophoresis of Non-Spherical Cell suspensions

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Engineering（科研） 2012年第10期4卷 88-93页

作者： Sakshin Bunthawin Jatuporn Kongklaew Adisorn Tuantranont Kata Jaruwongrangsri Thitima Maturos Biotechnology of Electromechanics Research Unit Science of Physics Faculty of Technology and Environment Prince of Songkla University Kathu Phuket 83120 Thailand Nano-Electronics and MEMs laboratory National Electronics and Computer Technology Center Pathumthani 12120 Thailand

A microchip interdigitated electrode with a sequential signal generator has been developed for traveling wave dielectrophoresis (twDEP) of biological cell suspensions. The electrode was fabricated on a microscope glass slide and coated with a 0.5 μm thickness of gold through a sputtering technique which was designed for large-scale inductions of cells rather than for individual cells as in previous versions of our device. As designed for a representative cell size of 10 μm, the electrode array was 50 μm in width to allow large numbers (>106) of cells to be processed. The sequential signal generator produces an arbitrary AC quadrature-phase to generate traveling electric field for a microchip interdigitated electrode. Each phase signal can be automatically altered and alternated with the other phases within interval time of 0.01-30 seconds (controlled by programming). We demonstrate the system could be used to estimate the dielectric properties of the yeast Saccharomyces cerivisiae TISTR 5088, the green alga Tetraselmis sp. and human red blood cells (HRBCs) through curve-fitting of dielectro- phoretic velocities and critical frequencies.

关键词： Traveling wave Dielectrophoresis Microchip Interdigitated Electrode Cell suspensions Dielectric Properties

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Photoelectrochemical Production of Hydrogen in Aqueous suspensions Nanoparticles Composites of CdS/ZnS

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Materials Sciences and Applications 2011年第11期2卷 1631-1638页

作者： Kasem K. Kasem Melissa Dahn Nida Zia Aubrey Finney 不详

Aqueous solutions of mixed CdS/ZnS semiconductor (SC) nanoparticle suspensions in phosphate buffers containing 10 mM [Fe(CN)6]4– were used for photochemical production of hydrogen via hydrated electron intermediates. CdS was doped with varying percentages of ZnS to expand the absorption range of the composite to the UV region. Results show that maximum generation of hydrated electrons by [Fe(CN)6]4– occurs at pH 6. Furthermore, native CdS amorphous nanoparticles give the greatest photocurrent. Studies also show that, in phosphate buffer, the steady state photocurrent was directly proportional to the CdS content in the mixture of CdS/ZnS. The aqueous nano-systems sustained their stability as indicated by the reproducibility of their photocatalytic activities. Solar radiated assemblies of CdS/ZnS/ [Fe(CN)6]4– sustained cyclic systems for continuous hydrogen production.

关键词： Photolysis Nanoparticles Hydrogen suspensions Cadmium Sulfide

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