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Midnight Salivary Cortisol and Other Effective Factors in the Graduation of Clinical suspect of Cushing Syndrome: Is There Any Reasonable Clinical Score?

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Open Journal of Endocrine and Metabolic Diseases 2013年第1期3卷 52-54页

作者： Meral Mert Refik Tanakol Hande Karpuzoglu Semra Abbasoglu Sema Yarman Harika Boztepe Faruk Alagol Istanbul University Istanbul Medical Faculty Department of Biochemistry Istanbul Turkey Istanbul University Istanbul Medical Faculty Department of Internal Medicine Division of Endocrinology and Metabolism Istanbul Turkey

Background: Diagnosis of Cushing’s Syndrome (CS) at the right time and with the right method is getting more important for the patients and clinicians due to high mortality rate. The most appropriate laboratory test will provide great benefits in terms of cost-effectiveness in the well-chosen group of patients. Selection of the high risk group is of crucial importance for the true diagnosis and treatment on time. Aim: The aim of this study was to evaluate the worth of the midnight salivary cortisol and to establish other effective factors in the graduation of clinical suspect of CS. Material and Methods: 115 patients were evaluated in weight, height, body mass index (BMI), waist/hip ratio, systolic, diastolic blood pressures, hirsutism, weight gain, purple-stria, plethore, buffalo-hump, supraclavicular fullness, temporal fat cushion, acnea, moonface, proximal muscle weakness, lower limb edema, ecchymosis, loss of libido, depression, diabetes mellitus, hypertension, allopecia of all patients were noted in the evaluation forms (23 findings). Patients were grouped according to clinical scores, low (16). Results: When we compare the groups in terms of midnight salivary cortisol, morning salivary cortisol after overnight dexamethasone suppression test, we found statistically significant relationship between the low and high clinical score groups, as well as between medium and high score groups (p: 0.0001). Urinary free cortisol was statistically significant only between low and high clinical score groups (p: 0.0001). Conclusion: This clinical scoring system which includes clinical signs and laboratory findings both, can be used for selection of the high risk group.

关键词： Salivary Cortsiol Clinical suspect Clinical Score Cushing’s Syndrome

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Sybase数据库被标记为“suspect”的解决方法

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电信技术 2001年第6期 40-42页

作者：周晓红宁夏邮电通信软件中心

根据维护“宁夏本地计费账务综合系统”Sybase数据库系统的经验和体会 ,对Sybase数据库系统出现的“currentdatabasehasbeenmarkedsuspect”错误问题进行两个方面的分析。

关键词：程序设计 suspect Sybase数据库软件维护

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谈谈suspect与doubt在用法上的差异

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大学英语 1992年第6期 73-74页

作者：甄艳华

在英语中,尽管suspeet与doubt这两个词在用法上存在着许多差异,但由于它们在词义上相近—都含有“怀疑、有疑问”的意思,因此往往不易准确地使用它们。笔者结合自己在教学中的一些体会,将其主要用法及区别归纳如下: 1.二者在词义上的差... 详细信息

在英语中,尽管suspeet与doubt这两个词在用法上存在着许多差异,但由于它们在词义上相近—都含有“怀疑、有疑问”的意思,因此往往不易准确地使用它们。笔者结合自己在教学中的一些体会,将其主要用法及区别归纳如下: 1.二者在词义上的差别: 1) suspect表示“怀疑有、

关键词： doubt suspect

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浅谈object、suspect和protest的微妙用法

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语言教育 1992年第8期 48-49页

作者：张莉

英语中有些动词的用法对学生来说十分微妙,我们叫它微妙动词(tricky verbs)。这类动词的微妙之处表现在两个方面:一是词义不易用汉语确切地解释清楚,二是由于搭配关系引起误解或造成使用上的困难。现将object、suspect和protest的微妙... 详细信息

英语中有些动词的用法对学生来说十分微妙,我们叫它微妙动词(tricky verbs)。这类动词的微妙之处表现在两个方面:一是词义不易用汉语确切地解释清楚,二是由于搭配关系引起误解或造成使用上的困难。现将object、suspect和protest的微妙用法归纳如下: 学生在学习object这个词的时候,往往只记住汉语释义是“反对”,并记住它的后面要跟to,由于这两个意思在脑子里扎根较深,所以往往忽视了。object与宾语从句连用时意义上发生了变化,当它与宾语从句连用时,从句是指“反对的理由”而不是指“反对的内容”。object that…是指出“…作为反对的理由”,而不是“反对或不赞成”。例如:

关键词：搭配关系宾语从句 object protest suspect 直接宾语 mother night never expensive

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解决Sybase数据库被标记为“suspect”的方法

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金融电子化 2003年第8期 64-64页

作者：林学刚中国人民银行徐州市中心支行

在使用 Sybase 数据库时,会遇到这样的问题:由于系统意外断电或人为误操作,使得数据库没有正常关闭,再开机进入系统时,数据库不能被打开,系统提示:数据库被挂起。出现数据库被挂起,有两种情况,一种是数据库所用设备正常,另一种是数据库... 详细信息

在使用 Sybase 数据库时,会遇到这样的问题:由于系统意外断电或人为误操作,使得数据库没有正常关闭,再开机进入系统时,数据库不能被打开,系统提示:数据库被挂起。出现数据库被挂起,有两种情况,一种是数据库所用设备正常,另一种是数据库所用设备被损坏,处理起来也有区别。下

关键词：数据库数据库系统 suspect Sybase

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Doubt和suspect

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英语沙龙（初级版） 2007年第6期 64-页

作者：张卫族

下面哪句表示"我料想是他打碎的玻璃窗"?I doubt that he broke the window.I suspect that he broke the ***和doubt是一对很容易混淆的动词。它们都表示"怀疑",但有一个根本区别。suspect对陈述的内容抱有肯定的态度,而doubt对陈述的... 详细信息

下面哪句表示"我料想是他打碎的玻璃窗"?I doubt that he broke the window.I suspect that he broke the ***和doubt是一对很容易混淆的动词。它们都表示"怀疑",但有一个根本区别。suspect对陈述的内容抱有肯定的态度,而doubt对陈述的内容抱有否定的态度。

关键词：玻璃窗 suspect Doubt

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Retinal nerve fiber layer changes based on historic CD4 nadir among HIV positive patients undergoing glaucoma evaluation

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International Journal of Ophthalmology(English edition) 2019年第5期12卷 789-794页

作者： Sarah H.Van Tassel Paul Petrakos Elizabeth Marlow Elizabeth Mauer Harjot K.Singh Anna M.Demetriades Department of Ophthalmology Weill Cornell Medicine Division of Biostatistics and Epidemiology Department of Healthcare Policy & ResearchWeill Cornell Medicine Division of Infectious Disease New York-Presbyterian Hospital/Weill Cornell Medicine

AIM: To determine relationships between retinal nerve fiber layer(RNFL) thickness and nadir CD4 cell count in human immunodeficiency virus(HIV) positive patients evaluated for glaucoma ***: Data were reviewed for 329 HIV positive patients evaluated for glaucoma suspicion. High-definition optical coherence tomography(OCT) RNFL measurements were obtained at least 6 mo apart. Analyses were performed to identify relationships between nadir CD4 count and RNFL ***: Totally 110 eyes of 55 patients met inclusion criteria, of which 46 eyes were from subjects with nadir CD4<200 cells/mm^3 and 64 had nadir CD4≥200 cells/mm^3. Patients with nadir CD4<200 cells/mm^3 had significantly thicker superior(119.7±18.6 μm) and temporal(63.8±11.7 μm) quadrants at time of initial OCT compared to the superior(112.8±16.8 μm, P=0.048) and temporal(57.1±11.9 μm, P=0.004) quadrants of patients with higher nadir CD4. This trend toward thicker RNFL among subjects with lower nadir CD4 cell counts persisted at the time of follow up OCT where participants with nadir CD4<200 cells/mm^3 showed average RNFL thickness in the superior and temporal quadrants of 117.9±18.3 μm and 63.8±12.8 μm, respectively, compared to a superior thickness of 110.5±16.9 μm(P=0.034) and temporal thickness of 57.3±11.6 μm(P=0.007) among those with higher nadir CD4. CONCLUSION: Patients with lower nadir CD4 cell counts have thicker RNFL in the superior and temporal quadrants compared to those with higher nadir CD4 counts. RNFL thickness in HIV positive patients may be affected by historic HIV disease control and should be considered when evaluating HIV positive patients for glaucoma.

关键词： glaucoma glaucoma suspect human immunodeficiency virus retinal nerve fiber layer

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Discriminating performance of macular ganglion cellinner plexiform layer thicknesses at different stages of glaucoma

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International Journal of Ophthalmology(English edition) 2019年第3期12卷 464-471页

作者： Melih Ustaoglu Nilgun Solmaz Feyza Onder Glaucoma Research Center Wills Eye Hospital Ophthalmology Clinic Sisli Hamidiye Etfal Training and Research Hospital Ophthalmology Clinic Haseki Training and Research Hospital

AIM: To determine the discriminating performance of the macular ganglion cell-inner plexiform layer(GCIPL) parameters between all the consecutive stages of glaucoma(from healthy to moderate-to-severe glaucoma), and to compare it with the discriminating performances of the peripapillary retinal nerve fiber layer(RNFL) parameters and optic nerve head(ONH) ***: Totally 147 eyes(40 healthy, 40 glaucoma suspects, 40 early glaucoma, and 27 moderate-to-severe glaucoma) of 133 subjects were included. Optical coherence tomography(OCT) was obtained using Cirrus HD-OCT 5000. The diagnostic performances of GC-IPL, RNFL, and ONH parameters were evaluated by determining the area under the curve(AUC) of the receiver operating characteristics. RESULTS: All GC-IPL parameters discriminated glaucoma suspect patients from subjects with healthy eyes and moderate-to-severe glaucoma from early glaucoma patients(Psuspects, whereas no RNFL or ONH parameter could discriminate between the two. The best parameters to discriminate glaucoma suspects from subjects with healthy eyes were superonasal GC-IPL, superior RNFL and average c/d ratio(AUC=0.746, 0.810 and 0.746, respectively). Discriminating performances of all the parameters for early glaucoma vs glaucoma suspect comparison were lower than that of the other consecutive group comparisons, with the bestGC-IPL parameters being minimum and inferotemporal(AUC=0.669 and 0.662, respectively). Moreover, minimum GC-IPL, average RNFL, and rim area(AUC=0.900, 0.858, 0.768, respectively) were the best parameters for discriminating moderate-to-severe glaucoma patients from early glaucoma ***: GC-IPL parameters can discriminate glaucoma suspect patients from subjects with healthy eyes, and also all the consecutive stages of glaucoma from each other(from glaucoma suspect to moderate-tosevere

关键词： retinal nerve fiber layer optic nerve head cirrus HD-OCT ganglion cell-inner plexiform layer glaucoma suspect

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Development of multiple mobile networks call detailed records and its forensic analysis

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Digital Communications and Networks 2019年第4期5卷 256-265页

作者： Emmanuel Abba A.M.Aibinu J.K.Alhassan Department of Cyber Security Science Federal University of TechnologyMinnaNigeria Department of Mechatronics Engineering Federal University of TechnologyMinnaNigeria

Call Detailed Records(CDR)are generated and stored in Mobile Networks(MNs)and contain subscriber’s information about active or passive usage of the network for various communication *** spatio-temporal nature of CDR makes them a valuable dataset used for forensic *** in technology have led to the seamless communication across Multiple Mobile Network(MMN),which poses a threat to the availability and integrity of CDR *** CDR implementation is capable of logging peer-to-peer communications over single connection only,thus necessitating improvements on how the CDR data is stored for forensic *** this paper,the problem is solved by identifying and conceptually modelling six new artifacts generated by such communication *** newly identified artifacts are introduced into the existing CDR for an incident capturing of the required data for forensic analysis during investigations involved in the MMN *** show an improved absolute speed of 0.0058 s for the MMN-CDR to associate a suspect with an incident,which is 0.0038 s faster than the speed of 0.0097s for the existing CDR to associate a suspect with an ***,a novel method for forensically tracking calls over the MMN has been *** MMN-CDR,when forensically analyzed,reveals an increase in time efficiency over the existing CDR due to its high absolute ***,higher accuracy and completeness percentage are both obtained.

关键词： CDR Investigation Multiple mobile networks suspect

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Utilization of Malaria Diagnostic Tests and Receipt of Anti-Malarial Drugs by Febrile Patients Attending Outpatient Clinics of Health Centre IV Facilities in Mukono District, Uganda

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Health 2014年第13期6卷 1628-1642页

作者： Rose Naigino Achilles Katamba Harriet M. Babikako Aggrey Mukose Makerere University School of Public Health College of Health Sciences Kampala Uganda

Background: Failure to demonstrate the presence of malaria parasites prior to treatment with anti-malarial drugs remains a challenge in Uganda, often resulting into over-prescription of anti-malarial drugs to febrile patients suspected of malaria. The aim of this study was to describe the role of utilization of malaria diagnostic tests and associated factors in the receipt of anti-malarial drugs among febrile patients suspected of malaria. Methods: In a cross-sectional study design, client-exit interviews with febrile patients and key-informant interviews with purposively selected health workers were conducted at outpatient clinics of health centre IV facilities in Mukono district. Data entry and analysis were done using EpiData 3.2 and STATA 10 respectively. Data were described using frequency distributions and proportions. Chi square was used in two by two tables, odds ratios as the measure of association and an alpha level of 0.05 was used in all significance tests. Results: Out of 408 respondents, the majority were female (252, 61.8%) and a third of the samples were aged five years and below. The mean age in years was 3.3 with a standard deviation of 2.1. More than half of the respondents (359, 88%) utilized malaria diagnostic tests and about half (241, 59%) received anti-malarial drugs. There were no statistically significant differences between utilizers and non-utilizers in most characteristics except age, history of indoor residual spraying and perceived satisfaction with services at outpatient clinics. Utilizers were 75% less likely to receive anti-malarial drugs than non-utilizers after controlling for age, sex and residence (OR: 0.25, 95%CI: 0.09, 0.66). Frequent power cut-offs as well as limited knowledge on malaria treatment guidelines amongst laboratory personnel were some of the major limitations to microscopic diagnosis of malaria. Conclusion: Utilizers were 75% less likely to receive anti-malarial drugs as opposed to non-utilizers. This implies that

关键词： Malaria Diagnostic Test Febrile Malaria suspect Utilizers Receipt of Anti-Malarial Drugs

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