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Frequency and Antimicrobials Susceptibility Pattern of <i>Staphylococcus aureus</i>Associated with Wound Infections in Surgery Department, Wad Madani Teaching Hospital, Sudan

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Pharmacology & Pharmacy 2021年第12期12卷 334-343页

作者： Sanaa M. Yousif Adam D. Abakar Bakri Y. M. Nour Salma O. Ibrahim Omer M. Abu Elhasan Mirgani A. Yousif Sitelbanat Yassin Hajer M. Hussien Mohamed Taj-Eldin Elhadi A. Ahmed National Blood Bank Ministry of Health Khartoum Sudan Department of Medical Parasitology Faculty of Medical Laboratory Sciences University of Gezira Wad Medani Sudan Department of Medical Microbiology Faculty of Medical Laboratory Sciences University of Gezira Wad Medani Sudan Wad-Madani College of Medical Sciences and Technology Wad Medani Sudan Faculty of Pharmacy University of Gezira Wad Medani Sudan

Background: Most community and hospital acquired infections are due to Staphylococcus aureus, these infections involve both local suppurative and systemic conditions. There is an increase in the incidence rates of acquiring resistant strains of Staphylococcus aureus in hospitals and community in Sudan. This study aims to detect frequency of Staphylococcus aureus isolated from surgical-sites infections (SSIs) and traumatic wounds, and to determine susceptibility to commonly used drugs. Methods: Prospective cross-sectional laboratory based study was followed, 250 patients admitted to Surgery Departments at Wad Madani Teaching Hospitals during 2019 and 2020 were recruited;with clinical manifestation of SSIs and or/traumatic wounds. Swab sample was taken from each participant and incubated aerobically on mannitol salt agar. Biochemical tests and 16rRNA gene used for Staphylococcus aureus identification. Antimicrobial susceptibility was accomplished using Kirby Bauer disc diffusion technique. Results: Infection rate of wounds in males and females equal 71% (17/250) and 29% (73/250), while infection rate in the age group of 41 to 60 y

关键词： Staphylococcus aureus surgical-sites Wounds Meropeneme Sudan

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