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Quality of life after surgical and endoscopic management of severe acute pancreatitis: A systematic review

World Journal of Gastrointestinal Endoscopy 2022年第7期14卷 443-454页

作者： Emmanouil Psaltis Chris Varghese Sanjay Pandanaboyana Manu Nayar Department of HPB and Transplant Surgery Newcastle upon Tyne NE77DNUnited Kingdom Department of Surgery Freeman HospitalNewcastle upon Tyne NE77DNUnited Kingdom Department of Surgery Faculty of Medical and Health SciencesUniversity of AucklandAuckland 1010New Zealand Population Health Sciences Institute Newcastle UniversityNewcastle upon Tyne NE17RUUnited Kingdom Department of Gastroenterology Freeman HospitalNewcastle upon Tyne NE77DNUnited Kingdom

BACKGROUND Treatment for severe acute severe pancreatitis(SAP)can significantly affect Health-related quality of life(HR-QoL).The effects of different treatment strategies such as endoscopic and surgical necrosectomy on HR-QoL in patients with SAP remain poorly *** To critically appraise the available evidence on HR-QoL following surgical or endoscopic necrosectomy in patient with *** A literature search was performed on PubMed,Google^(TM) Scholar,the Cochrane Library,MEDLINE and Reference Citation Analysis databases for studies that investigated HR-QoL following surgical or endoscopic necrosectomy in patients with *** collected included patient characteristics,outcomes of interventions and HR-QoL-related *** Eleven studies were found to have evaluated HR-QoL following treatment for severe acute pancreatitis including 756 *** studies were randomized trials,four were prospective cohort studies and four were retrospective cohort studies with prospective *** studies compared HR-QoL following surgical and endoscopic *** metrics of HR-QoL were used including Short Form(SF)-36 and *** randomized trial and one cohort study demonstrated significantly improved physical scores at three months in patients who underwent endoscopic necrosectomy compared to surgical *** prospective study that examined HR-QoL following surgical necrosectomy reported some deterioration in the functional status of the *** the other hand,a cohort study that assessed the long-term HR-QoL following sequential surgical necrosectomy stated that all patients had SF-36>60%.In the only study that examined patients following endoscopic necrosectomy,the HR-QoL was also very *** studies investigated the quality adjusted life years suggesting that endoscopic and surgical approaches to management of pancreatic necrosis were comparable in cost ***,regarding HR-QoL between open necrose

关键词： Acute pancreatitis Pancreatic necrosis surgical necrosectomy Endoscopic necrosectomy Minimally invasive drainage Quality of life

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