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Investigation of serum calcium and vitamin D levels in superior semicircular canal dehiscence syndrome: A case control study

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Journal of Otology 2023年第1期18卷 49-54页

作者： Theofano Tikka Mohd Afiq Mohd Slim Trung Ton Anna Sheldon Louise J.Clark Georgios Kontorinis Department of Ear Nose and Throat SurgeryQueen Elizabeth University Hospital345 Govan RdGlasgowG514TFUnited Kingdom

Objective: It remains unknown whether calcium metabolism has any effect on the clinical presentation of superior semicircular canal dehiscence(SSCD). Our aim was to analyse the adjusted calcium and vitamin D levels in SSCD patients compared to a control ***: This was a prospective case-control study performed in a tertiary referral center, university teaching hospital in the UK. It included all new patients with SSCD seen in a dedicated skull base clinic over a 5-year period(2015-2019) compared to a gender and age matched control group. The main outcome of the study was adjusted calcium and Vitamin D levels between the two ***: A total of 31 SSCD patients were recruited with a matched number of control patients. The mean Vitamin D level on the SSCD group was 44.8 nmoL/l(SD: 20.8) compared to 47.5 nmoL/l(SD: 27.4) on the control group(p = 0.702). Mean Adjusted calcium level was 2.34 mmoL/l(SD: 0.7) for SSCD compared to2.41 mmoL/l(SD: 0.11) for controls(p = 0.01), being within normal limits for both the SSCD and the control ***: Our study did not identify a link between Vitamin D levels and presence of SSCD. Normal adjusted calcium values were found in both groups. Despite that a statistically significant lower calcium level was found in the SSCD group which could indicate that suboptimal levels of calcium may affect the micro-environment of the otic capsule at the SSC region.

关键词： superior semicircular canal Dehiscence Calcium Vitamin D Metabolism

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Bilateral superior semicircular canal Dehiscence without Signs of Vestibular Involvement about a Case

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International Journal of Otolaryngology and Head & Neck Surgery 2022年第2期11卷 82-90页

作者： Habib Ould Cheikh El Wely Saloua Ouraini Mohamed Moumni Jalal Oubenjah Mohamed Zalagh Bouchaib Hemmaoui Nourredine Errami Fouad Benariba Otorhinolaryngology and Head & Neck Surgery Department Mohamed V Military Hospital Rabat Morocco

superior semicircular canal dehiscence (SSCD) is a rare entity recently described whose typical clinical symptomatology is represented by dizziness triggered by a variation of pressure. We reported a case of SSCD which was diagnosed thanks to computed tomography (CT) scan of the petrous bone conducted systematically in front of mixed deafness with normal eardrum. The SSCD was bilateral and was revealed by mixed deafness on the left side and perception deafness on the right with a normal eardrum without the notion of vertigo. The cervical vestibular evoked myogenic potential (cVEMP) and an ultra-high resolution CT scan of the petrous bones in coronal and sagittal sections allowed the diagnosis. The SSCD should be considered in the presence of any conductive or mixed hearing loss with a normal eardrum. The CT scan in coronal and sagittal submillimetric sections allows the diagnosis.

关键词： superior semicircular canal Dehiscence Deafness

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