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effective treatment of post-intubation subglottic stenosis in children with holmium laser therapy and cryotherapy via flexible bronchoscopy

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Pediatric Investigation 2019年第1期3卷 9-16页

作者： Anxia Jiao Fang Liu Andrew D.Lerner Xiaochun Rao Yan Guo Chenfang Meng Yuena Pan Gan Li Zheng Li Fang Wang Jing Zhao Yuyan Ma Xicheng Liu Xin Ni Kunling Shen Interventional Pulmonology Department Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina China National Clinical Research Center for Respiratory Diseases BeijingChina Division of Pulmonary and Critical Care Medicine Johns Hopkins University School of MedicineBaltimoreMDUSA Respiratory Department Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina Pediatric Intensive Care Unit Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina Department of Anesthesiology Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina Department of Otolaryngology Head and Neck SurgeryBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck SurgeryMOE Key Laboratory of Major Disease in ChildrenBeijing Pediatric Research InstituteBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijingChina

Importance:Post-intubation subglottic stenosis(SGS)in children can be life *** treatment varies and lacks a universally accepted ***:We performed a prospective study to assess the safety and feasibility of holmium laser combined with cryotherapy delivered via flexible bronchoscopy for the treatment of post-intubation SGS in ***:This study involved all patients with post-intubation SGS seen at the Interventional Pulmonology Department of Beijing Children's Hospital between July 2014 and December *** laser treatment and cryotherapy was then performed under flexible bronchoscopy,whose parents refused to accept the alternative standard treatment of tracheotomy and balloon dilation under direct ***:Sixteen patients with post-intubation SGS were included in this *** ranged from 2 months to 12.25 years *** to the Cotton-Myer grading system,three cases were Grade II,12 cases were Grade III,and one case was Grade *** to the McCaffrey system,eight cases were Stage 1,two cases were Stage 2,and six cases were Stage *** average number of procedures was *** of the 16 patients achieved clinical *** patient achieved clinical *** average treatment course duration was 55.31 *** severe complications were ***-treatment clinical symptoms,endoscopic findings and quality of life showed marked ***:Our study supports the conclusion that holmium laser treatment combined with cryotherapy via flexible bronchoscopy appears to be a safe and feasible treatment for post-intubation SGS in children.

关键词： subglottic stenosis Flexible bronchoscopy Holmium laser Cryotherapy Children

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Laryngotracheal stenosis Following Intubation for COVID-19 Pneumonia: A Report of Two Cases

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International Journal of Otolaryngology and Head & Neck Surgery 2022年第5期11卷 234-241页

作者： Derar Al-Domaidat Mohammed Algarni Ro’a Alshaikh Hasan Hosam Amoodi Otolaryngology Department Dr. Soliman Fakeeh Hospital Jeddah Saudi Arabia Otolaryngology Department King Saud Bin Abdulaziz University for Health Science Jeddah Saudi Arabia Internal Medicine Department Dr. Soliman Fakeeh Hospital Jeddah Saudi Arabia Department of Surgery Jeddah University Jeddah Saudi Arabia

Benign laryngotracheal stenosis (LTS) is a debilitating and potentially life-threatening condition that is commonly caused by iatrogenic events as a result of endotracheal intubation or tracheostomy. Numerous cases are being published for patients with coronavirus disease 2019 (COVID-19) who end up with severe LTS after prolonged intubation or tracheostomy. Here, we presented two cases of LTS due to prolonged intubation after severe COVID-19 pneumonia. The characteristic of these two cases is that both of them needed second time intubation and were readmitted because of severe dyspnoea and all the workup for post-COVID-19 complications were investigated except the LTS which was later diagnosed after one month of suffering of these patients.

关键词： subglottic stenosis Tracheal stenosis Laryngotracheal stenosis Prolonged Intubation COVID-19

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