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Indoor Allergen Levels and Household Distributions in Nine Cities Across China

Biomedical and Environmental Sciences 2015年第10期28卷 709-717页

作者： ZHENG Yi Wu LAI Xu Xin ZHAO De Yu ZHANG Chun Qing CHEN Jian Jun ZHANG Luo WEI Qing Yu CHEN Shi LIU En Mei NORBACK Dan GJESING Birgitte ZHONG Nan Shan SPANGFORT D.Michael Research Asia Pacific ALK Department of Respiratory Medicine the Affiliated Children's Hospital of Nanjing Medical University State Key Laboratory of Respiratory Disease the First Affiliated HospitalGuangzhou Medical University ENT Department of Wuhan Union Hospital ENT Department of Beijing Tongren Hospital Allergology Department of Shenyang 202 Hospital Asthmatic Children's Immunotherapy Center of People's Hospital of Hainan Province Respiratory Department Children's Hospital of Chongqing Medical University Department of Medical Science and Occupational and Environmental Medicine University HospitalUppsala University

Objective Chinese allergic subjects have high levels of sensitization to house dust mite （HDM） and other indoor allergens. This study quantifies common indoor allergen levels in Chinese households. Methods Dust samples were collected from nine cities. Major allergens Der p 1 and Der f I from Dermatophagoides pteronyssinus and D. farinae, and specific antigens of Blomia tropicalis, Tyrophagus putrescentiae, Acarus siro, and cockroach species Blattella germanica and Periplaneta americana were measured by *** HDM allergens were found in dust samples from bedding in 95% of the Chinese households. The median levels varied from 〈0.006 to 9.2 μg/g of dust, depending on the city. The percentages of households having HDM allergen levels associated with the risk of developing allergy sensitization and asthma were 65% and 25%, respectively. Specific antigens of the storage mite and cockroach were only found in samples from the southern and tropical regions of China. Levels of mite allergens were generally higher in samples from bedding compared to samples from the living room, even for storage mites, whereas levels of cockroach antigens were higher in the living room *** HDM allergens are present in bedding dust samples from most Chinese households. Cities in southern and central China have relatively high levels of HDM major allergens compared to cities in northern and western China. Antigens of storage mites and cockroaches are not as common as HDM allergens.

关键词： Dermatophagoides pteronyssinus D. farinae House dust mite Indoor allergen storage mite

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