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Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation

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Bioactive Materials 2019年第1期4卷 168-188页

作者： Adela Helvia Martínez Sánchez Maryam Omidi Marcus Wurlitzer Marceline Manka Fuh Frank Feyerabend Hartmut Schlüter Regine Willumeit-Römer Bérengère J.C.Luthringer Division of Metallic Biomaterials Institute of Material ResearchHelmholtz-Zentrum GeesthachtMax Planck Strasse 121502GeesthachtGermany Institute of Clinical Chemistry and Laboratory Medicine Mass Spectrometric ProteomicsUniversity Medical Center Hamburg-EppendorfMartinistraße 5220246HamburgGermany

Treatment of physeal fractures(15%–30%of all paediatric fractures)remains a challenge as in approximately 10%of the cases,significant growth disturbance may *** Magnesium-based implants represent a strategy to minimize damage(i.e.,load support until bone healing without second surgery).Nevertheless,the absence of harmful effects of magnesium-implants and their degradation products on the growth plate should be ***,the proteome of human mesenchymal stem cells undergoing chondrogenesis was evaluated when exposed to the products of various Magnesium-based materials *** results of this study indicate that the materials induced regulation of proteins associated with cell chondrogenesis and cartilage formation,which should be beneficial for cartilage regeneration.

关键词： stem cells differentiation Chondrogenesis Proteomics Magnesium biomaterial Biodegradable implant

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An Overview of the Use of Medicinal Plants in Regenerative Dentistry

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Open Journal of Stomatology 2023年第1期13卷 50-88页

作者： Sara Dhoum Samir Ibenmoussa Mustapha Sidqui Faculty of Dental Medicine Hassan II University Casablanca Morocco Faculty of Medicine and Pharmacology Hassan II University Casablanca Morocco

Aim: The oral cavity has the particularity to host multiple hard and soft tissues, in this paper, we will discuss the current therapies that lead to cell differentiation by regenerative therapies and the future alternatives proposed by medicinal plants and all the regenerative potential of these different tissues. Material and Methods: A detailed review of the literature through the various search engines: Scopus, PubMed, google scholar, Cochrane, etc., uses the selected keywords to explore the effect of the regenerative potential of several medicinal plants. Results: Through our research, we have proceeded to sort different medicinal plants, according to their repairing and regenerative potential on the different tissues of the oral cavity. Conclusion: Future studies are conceivable to explore the opportunities and potential provided by medicinal plants in the field of regenerative dentistry.

关键词： Medicinal Plants Medicinal Herbs Tissue Regeneration Enamel Remineralization Dental Pulp Periodontal Regeneration Bone Regeneration Wound Healing stem cells differentiation Odontoblastic differentiation Oral Cavity Herbal Extract Oral Tissues

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