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smoking cessation prior to elective total joint arthroplasty results in sustained abstinence postoperatively

World Journal of Orthopedics 2024年第7期15卷 627-634页

作者： Billy Insup Kim Jeffrey O'Donnell Colleen M Wixted Thorsten Markus Seyler William A Jiranek Michael Paul Bolognesi Sean Patrick Ryan Department of Orthopedic Surgery Hospital for Special SurgeryNew YorkNY 10021United States Department of Orthopedic Surgery New York UniversityNew YorkNY 10003United States Department of Orthopedic Surgery Duke University HospitalDurhamNC 27560United States

BACKGROUND Tobacco use is a well-documented modifiable risk factor for perioperative complications.AIM To determine the tobacco abstinence rates of patients who made cessation efforts prior to a total joint arthroplasty(TJA)procedure.METHODS A retrospective evaluation was performed on 88 self-reported tobacco users who underwent TJA between 2014-2022 and had tobacco cessation dates within 3 mo of surgery.Eligible patients were contacted via phone survey to understand their tobacco use pattern,and patient reported outcomes.A total of 37 TJA patients participated.RESULTS Our cohort was on average 61-years-old,60%(n=22)women,with an average body mass index of 30 kg/m2.The average follow-up time was 2.9±1.9 years.A total of 73.0%(n=27)of patients endorsed complete abstinence from tobacco use prior to surgery.Various cessation methods were used perioperatively including prescription therapy(13.5%),over the counter nicotine replacement(18.9%),cessation programs(5.4%).At final follow up,43.2%(n=16)of prior tobacco smokers reported complete abstinence.Patients who were able to maintain cessation postoperatively had improved Patient-Reported Outcomes Measurement Information System(PROMIS)-10 mental health scores(49 vs 58;P=0.01),and hip dysfunction and osteoarthritis outcome score for joint replacement(HOOS.JR)scores(63 vs 82;P=0.02).No patients in this cohort had a prosthetic joint infection or required revision surgery.CONCLUSION We report a tobacco cessation rate of 43.2%in patients undergoing elective TJA nearly 3 years postoperatively.Patients undergoing TJA who were able to remain abstinent had improved PROMIS-10 mental health scores and HOOS.JR scores.The perioperative period provides clinicians a unique opportunity to assist active tobacco smokers with cessation efforts and improve postoperative outcomes.

关键词： smoking cessation Total joint arthroplasty Outcomes Tobacco use Postoperative abstinence

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Persuasive Technology for the Future of smoking cessation^*

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Advances in Internet of Things 2024年第2期14卷 36-52页

作者： Fatimah Dera M. Alshahrani College of Computer Science King Khalid University (KKU) Abha KSA

This paper explores the integration of persuasive technology into smoking cessation efforts through the development and evaluation of a mobile app, “No-Smoke.” Leveraging compelling features like social support, tracking, planning, and motivation, the app aims to augment user engagement and support the process of quitting smoking. The efficacy of these features has been substantiated through both automated testing and user feedback, highlighting their potential to enhance awareness, motivation, and behavior modification. Despite notable successes, limitations, including a limited user base and uncertainties regarding long-term efficacy, have been acknowledged, stemming from the inherent complexities of smoking cessation. Nevertheless, based on user experiences and feedback, “No-Smoke” represents a promising advancement in the use of technology for public health interventions, particularly in the realm of smoking cessation. To address existing challenges, future research is recommended to encompass a comprehensive, long-term study involving a larger and more diverse user base. Additionally, further investigation should focus on personalization enhancements and the integration of machine learning algorithms to better understand and respond to user behavior.

关键词： Persuasive Technology smoking cessation Mobile App

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When smoke meets gut:deciphering the interactions between tobacco smoking and gut microbiota in disease development

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Science China(Life Sciences) 2024年第5期67卷 854-864页

作者： Bo Chen Guangyi Zeng Lulu Sun Changtao Jiang Center of Basic Medical Research Institute of Medical Innovation and ResearchPeking University Third HospitalBeijing 100191China Department of Physiology and Pathophysiology School of Basic Medical SciencesState Key Laboratory of Vascular Homeostasis and RemodelingPeking UniversityBeijing 100191China Center for Obesity and Metabolic Disease Research School of Basic Medical SciencesPeking UniversityBeijing 100191China State Key Laboratory of Women’s Reproductive Health and Fertility Promotion Peking UniversityBeijing 100191China Department of Endocrinology and Metabolism Peking University Third HospitalBeijing 100191China

Tobacco smoking is a prevalent and detrimental habit practiced worldwide,increasing the risk of various diseases,including chronic obstructive pulmonary disease(COPD),cardiovascular disease,liver disease,and cancer.Although previous research has explored the detrimental health effects of tobacco smoking,recent studies suggest that gut microbiota dysbiosis may play a critical role in these outcomes.Numerous tobacco smoke components,such as nicotine,are found in the gastrointestinal tract and interact with gut microbiota,leading to lasting impacts on host health and diseases.This review delves into the ways tobacco smoking and its various constituents influence gut microbiota composition and functionality.We also summarize recent advancements in understanding how tobacco smoking-induced gut microbiota dysbiosis affects host health.Furthermore,this review introduces a novel perspective on how changes in gut microbiota following smoking cessation may contribute to withdrawal syndrome and the degree of health improvements in smokers.

关键词： tobacco smoking gut microbiota dysbiosis nicotine smoking cessation

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Impact of smoking cessation counseling among acute myocardial infarction patients on post-hospitalization mortality rates:a systematic review

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Frontiers of Nursing 2022年第2期9卷 135-142页

作者： Eyad Abu Alhaijaa Ismael Alblishi Mohammad Alnaeem Jafar Alasad Alshraideh Patient Safety and Experience Department.Abdali Medical Center Amman 9662Jordan Al-Istishari Hospital Amman 11184Jordan Faculty of Nursing University of JordanAmman 11942Jordan Clinical Nursing Department Faculty of NursingUniversity of JordanAmman 11942Jordan

Objective:The current systematic review aimed to assess the impact of smoking cessation counseling(SCC)on patients’short-and long-term mor tality after acute myocardial infarction(AMI).Methods:The Cochrane guidelines were used to conduct a systematic review of Medline(Pub Med),Science Direct,CINAHL Cochrane database,and Google Scholar for studies on the impact of SCC on AMI patients’mor tality.Results:Five studies were found to meet the predefined inclusion criteria.Smoker patients were not routinely counseled to quit smoking during their post-AMI hospital stay.Studies showed a reduction in mor tality among AMI patients’who received SCC compared with patients who did not receive it.Conclusions:SCC during hospitalization and after discharge is a simple and cost-effective intervention that improves AMI patients’survival.

关键词： acute myocardial infarction counseling mortality nursing smoking cessation

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Nicotine gum or patch treatment for smoking cessation and smoking reduction： a multi-centre study in Chinese physicians

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Frontiers of Medicine 2014年第1期8卷 84-90页

作者： Dan Xiao Nanshan Zhong Chunxue Bai Qingyu Xiu Canmao Xie Dayi Hu Yun Mao Roland Perfekt Elisabeth Kruse Qing Li John Jiangnan Liu Chen Wang Beijing Chao-Yang Hospital Capital Medical University WHO Collaborating Center for Tobacco or Health Beijing 100020 China Beijing Institute of Respiratory Medicine Beij'ing 100020 China Department of Respiratory Capital Medical University Beijing 100069 China Guangzhou Institute of Respiratory Disease 1st Affiliated Hospital Guangzhou Medical College Guangzhou 520120 China Zhongshan Hospital Fudan University Shanghai 200032 China Changzheng Hospital 2nd Military Medical University Shanghai 200003 China 1st Affiliated Hospital Sun Yat-sen University Guangzhou 510080 China people's Hospital Peking University Beijing 100044 China Shanghai Johnson & Johnson Pharmaceuticals Shanghai 200245 China McNeil AB Helsingborg Sweden Johnson & Johnson New Jersey USA Research Centre of Respiratory Medicine in Beijing Hospital Ministry of Health of the People 1's Republic of China Beijing 100730 China

In China, around 23% of physicians （41% male, 3% female） currently smoke. Pharmacotherapy for tobacco dependence is available, but is not widely used in China. The purpose of this study was to estimate the effectiveness and the safety on smoking cessation of nicotine gum and nicotine patch in Chinese healthcare professionals. Three hundred regular smokers motivated to quit were recruited from six hospitals in China. All subjects were accepted nicotine replacement therapy, and they could choose nicotine gum （2 mg or 4 mg, depending on baseline smoking level） or nicotine patch （15 mg/16 h） for 12 weeks, with a 12-week follow-up. Limited behavioural support was provided. At Week 24, the 2-24 weeks continuous abstinence rate （verified by expired carbon monoxide） was 17%, the point prevalence abstinence rate （no smoking since the previous visit） was 35%, and 38% of subjects had continuously reduced their daily cigarette consumption by at least 50% versus baseline. Compliance with treatment was good, particularly with patch. No serious adverse event was reported, and most adverse events were mild or moderate. The most common treatment-related adverse events were gastro- intestinal （both gum and patch） and local irritation symptoms. Nicotine patch and gum were well tolerated in Chinese smokers. Abstinence rates were comparable to those previously reported with nicotine replacement therapy, and many smokers who did not quit substantially reduced their cigarette consumption.

关键词： nicotine replacement therapy smoking cessation Chinese physicians

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Effect of smoking cessation on airway inflammation of rats with chronic bronchitis

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Chinese Medical Journal 2007年第17期120卷 1511-1516页

作者： LI Qing-yun HUANG Shao-guang WAN Huan-ying WU Hua-cheng ZHOU Tong LI Min DENG Wei-wu Department of Respiratory Medicine Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Pathology Ruijin Hospital ShanghaiJiao Tong University School of Medicine Shanghai 200025 China Department of N ephrology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China

Background smoking is the major cause of airway inflammation in chronic obstructive pulmonary disease （COPD）, and smoking cessation is regarded as one of the important strategies for prevention and treatment of the inflammation. The inflammation of the chronic airway may be present and deteriorated even if the COPD patients stop smoking. Whether and how early smoking cessation affects the progress of inflammation is still obscure. This study was conducted to find the appropriate time for smoking cessation to terminate the airway inflammation in rats with smoke-induced chronic bronchitis. Methods A rat model of COPD was established by passively inhaling smoke mixture. Fifty-four young male Sprague-Dawley rats were randomly divided into 9 groups with different periods of smoke exposure and different time points of cessation. The inflammation markers to be detected included inflammatory cells in the bronchoalveolar lavage fluid （BALF）, the myeloperoxidose （MPO） activity, the morphologic changes and the expression of ICAM-1 on the airway epithelium. Results When smoking was terminated at early stage, the inflammatory markers and related indexes were different from those of the typical chronic bronchitis group （group M7）（P〈0.01）. The pathologic score of group SC7 （2 weeks of smoking cessation after occurrence of typical chronic bronchitis ） was not different from that of group M7, and the level of ICAM-1 was still up-regulated （compared to group M7, P〉0.05）. Meanwhile, most of inflammatory cells in BALF were neutrophils compared to other groups （P〈0.01）.When smoking was terminated, the MPO activity was significantly lower than that of group M7 （P〈0.01）. Conclusions smoking cessation at early stage can effectively inhibit the inflammatory reaction of COPD. Once chronic bronchitis occurs, little could be improved by smoking cessation.

关键词： smoke chronic bronchitis inflammation smoking cessation

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Impact of weight gain following smoking cessation on one-year outcome after drug-eluting stent implantation

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Chinese Medical Journal 2012年第6期125卷 1041-1046页

作者： FAN Xiao-ming LU An-kang SHEN Wei-feng WU Qi-hong MA Xiao-ye YANG Er-li ZHANG Rui-Yan ZHANG Shi-jia Department of Cardiology Rui Jin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Cardiovascular Center of Xinqiao Hospital Third Military Medical University Chongqing 400037 China

Background Weight gain following smoking cessation increases cardiovascular risk, but its effects on prognosis after percutaneous coronary intervention （PCI） remain unclear. This study aimed to investigate the relationship between weight gain post smoking cessation and one-year clinical outcome in patients who underwent PCI with drug-eluting stent （DES）. Methods A total of 895 consecutive male smoking patients were divided into quitters （n=437） and continuers （n=458） according to their smoking status after PCI. Weight gain, major adverse cardiac events （MACE, including cardiac deaths, myocardial infarction and revascularization）, and recurrent angina were recorded during follow-up for one year. Results Average weight gain in quitters was more than that in continuers （1.5 kg vs. -0.03 kg, P〈0.001）. Weight was unchanged or increased by more than 1.5 kg in 78.17% of continuers, while 50.57% of quitters had a weight gain of less than 1.5 kg. Compared with continuers, MACE in quitters was significantly reduced after PCI （6.12% vs. 4.81%, P=0.049）, especially recurrent angina （13.97% in continuers vs. 9.84% in quitters, P=0.027）. After adjusting for weight gain and other factors, smoking cessation was independently associated with a lower risk of MACE and recurrent angina （0R=0.73, P=0.035）. However, weight gain 〉1.5 kg （OR=1.55, P=0.026） could curtail the benefits from smoking cessation. Conclusions Weight gain may reduce the benefits of smoking cessation after PCI with DES implantation. Thus, although smoking cessation is recommended after PCI, weight control should also be highly encouraged for these patients.

关键词： smoking smoking cessation coronary artery disease weight gain

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Effect of acupuncture treatment on smoking cessation in smokers from Hong Kong

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Journal of Traditional Chinese Medicine 2016年第5期36卷 634-639页

作者： Wang Yingying Liu Zhao Zhang Ou Chen Min Huang Lingling Wu Yuan Zhang Fanfan Wu Guanyi He Xiuqing Yang Jinsheng Institute of Acupuncture and Moxibustion China Academy of Chinese Medical Sciences Beijing 100700 China Tobacco Medicine Research and Clinical smoking cessation Center China-Japan Friendship Hospital Beijing 100029 China Acupuncture specialist centre of Hong Kong Pok Oi Hospital Hong Kong China

OBJECTIVE: To analyze the characteristics of smokers treated with acupuncture for smoking cessation in Hong Kong.METHODS: A total of 2051 subjects were recruited in a clinical pilot research project "acupuncture for smoking cessation", which was conducted jointly by Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences and Hong Kong Pok Oi Hospital from January of 2011 to December of 2013. The characteristics of study subjects, including baseline information, smoking background, intention to quit and influencing factors were analyzed.RESULTS: The majority of subjects treated with acupuncture for smoking cessation in Hong Kong was male(66.7%), but the proportion of female smokers in this study(33.3%) was higher than that of female smokers in Hong Kong population(13.8%, P smoking was 25.49 years. The number of cigarettes smoked per day was 17.57 cigarettes.Fagerstrom Test for Nicotine Dependence(FTND)was 5.29 points. Most of the subjects had attempted quitting smoking(81.42%). The confidence index(7.44 points) and the readiness to quit smoking(8.13 points) were high. Subjects quitting smoking were mostly due to health cause(81.91%). The majority of subjects were at the level of middle school(61.63%). The higher the educational level was, the lower the tobacco dependence was and the higher the confidence in successfully quitting smoking was. 50.27% of subjects chose acupuncture for smoking cessation mainly through friends, television and network publicity. Subjects who had received acupuncture had the highest confidence index, while those who wanted to try a new method had the lower confidence index.CONCLUSION: Acupuncture for smoking cessation was more popular in female smokers, especially those aged 31-40 years. The effectiveness of acupuncture-smoking cessation was most significant in the smokers over 60.

关键词： Acupuncture smoking cessation Tobacco use disorder

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Evaluation of 3-day smoking cessation training course for doctors from 38 cities in China

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Chinese Medical Journal 2012年第7期125卷 1338-1340页

作者： ZHANG Chun-mei XIAO Dan Robea West Susan Michie Ronald Troughton Peter Hajek WANG Chen Department of Respiratory Medicine Beijing Chao-Yang HospitalCapital Medical UniversityBeijing 100020China Beijing Hospital Ministry of HealthBeijing 100730China

Background The World Health Organization＇s ＂Framework Convention on Tobacco Control＂ came into effect in China in 2006. Since then, a series of tobacco control measures has been undertaken, including the first step to establish a coordinated network of stop-smoking clinics in Chinese hospitals. Training for stop-smoking specialists has been traditionally provided via printed materials. This study evaluated the outcomes of the first two intensive 3-day courses in smoking cessation in China run in collaboration with experts who provide training to UK Specialist Stop smoking Service. Methods Eighty-four doctors from 38 cities in China responsible for stop-smoking treatment in 20 provinces and four autonomous regions participated in the training courses. Participants＇ knowledge competencies and self-efficacy were assessed before and after the authentication training. Results The training significantly improved participants＇ knowledge, skills and self-efficacy across different domains. Forty-eight participants were finally certified as ＂smoking cessation specialist＂. Conclusions The UK model of face-to-face training was acceptable and effective in China. A relatively brief intensive training program can generate significant improvements in skills, knowledge, and readiness to engage in smoking cessation activities.

关键词： smoking cessation certification continuing medical education self-efficacy

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Motivations, Challenges and Coping Strategies for smoking cessation: Based on Multi-ethnic Pregnant Couples in Far Western China

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2017年第3期37卷 439-445页

作者：白雪陈江芸方子张霄艳王方潘正琼方鹏骞 School of Health and Medicine Management Tongji Medical College Huazhong University of Science and Technology Department of Financial Management Tongji Hospital Tongji Medical College Huazhong University of Science and Technology School of Policy and Public Administration Hubei University Medical Department Wuhan General Hospital of Guangzhou Military Command

The present study aimed to clarify the smoking cessation motivations, challenges and coping strategies among pregnant couples. A qualitative design using a grounded theory approach was applied. Data were collected by individual semi-structured interviews with 39 married individuals(21 non-smoking pregnant women and 18 smoking or ever-smoking men with a pregnant wife) and 3 imams in an ethnically diverse region of far western China. The most common theme for smoking cessation motivation was 'embryo quality'(i.e., a healthier baby), followed by family's health. Most interviewees reported that husband's withdrawal symptoms were the greatest challenge to smoking cessation, followed by the Chinese tobacco culture. Coping strategies given by the pregnant women typically involved combining emotional, behavioral and social interventions. Social interventions showed advantages in helping to quit smoking. Pregnancy appears to be a positive stimulus for pregnant couples' smoking cessation. Our results suggest that pregnancy, a highly important life event, may help to reduce barriers to smoking cessation at the social level(e.g., limiting access to cigarettes, avoiding temptation to smoke), but does little to help with the withdrawal symptoms. Professional guidance for smoking cessation is still necessary.

关键词： smoking cessation pregnant couple motivations challenges coping strategies

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