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Endoscopic diagnosis of early-stage primary esophageal small cell carcinoma: Report of two cases

World Journal of Clinical Cases 2021年第11期9卷 2562-2568页

作者： Li-Mian Er Yan Ding Xiao-Fang Sun Wen-Qian Ma Li Yuan Xiu-Li Zheng Na-Na An Ming-Li Wu Department of Endoscopy The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina Department of Pathology The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina Department of Endoscopy People's Hospital of XingtaiXingtai 054000Hebei ProvinceChina

BACKGROUND Primary esophageal small cell carcinoma(PESCC)is a highly aggressive malignancy,and its detailed clinical behaviors have remained virtually *** of the rapid tumor progression,the diagnosis of esophageal small cell carcinoma at early stage is extremely difficult in clinical ***,only a handful of PESCC cases have been *** SUMMARY Case 1:A 62-year-old man was diagnosed with an esophageal submucosal tumor by *** ultrasonography showed a 0.8 cm low echo nodule in the muscularis *** the patient refused to undergo endoscopic resection,neoplasia was detected by endoscopy 1 year *** 2:A 68-year-old woman was diagnosed as having an esophageal submucosal tumor by endoscopy at a local *** 2 wk later,we performed endoscopic ultrasonography and found a 1 cm low echo nodule in the muscularis mucosa;the submucosal was thinner than normal but still continuous;mucosal hyperemia and erosion were found on the surface of the *** submucosal dissection(ESD)was performed and the histopathological finding showed a small cell carcinoma invading the submucosal *** Early esophageal small cell carcinoma shows submucosal infiltrating growth with a hypoechoic mass in the muscularis mucosa as diagnosed by endoscopic *** is easily misdiagnosed as submucosal *** manifestations should be identified and pathological biopsies should beemployed. ESD may be performed to provide an opportunity for early treatmentof PESCC.

关键词： Primary esophageal small cell carcinoma Early stage Endoscopic submucosal dissection Endoscopic ultrasonography small submucosal masses Poor prognosis Case report

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