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Improving CAD Hemorrhage detection in Capsule Endoscopy

Journal of Biomedical Science and Engineering 2021年第3期14卷 103-118页

作者： Polydorou Alexios Sergaki Eleftheria Polydorou Andreas Barbagiannis Christos Vardiambasis Ioannis George Giakos Zervakis Michail School of Electrical and Computer Engineering Technical University of Crete Chania Greece Department of Surgery School of Medicine National and Kapodistrian University of Athens Athens Greece Department of Electronic Engineering Faculty of Engineering Hellenic Mediterranean University Chania Crete Greece School of ECE Manhattan College New York USA

This study explores an automated framework to assist the recognition of hemorrhage traces and bleeding lesions in video streams of small bowel capsule endoscopy (SBCE). The proposed methodology aims to achieve fast image control (bleeding index and blood-color chart, which inspects all remaining frames of the footage and identifies pixels that reflect active or potential hemorrhage in color. The bleeding index and blood-color chart are estimated of the chromatic thresholds in RGB and HSV color spaces, and have been extracted after experimenting with more than 3200 training images, derived from 99 videos of a pool of 138 patients. The dataset has been provided by a team of expert gastroenterologist surgeons, who have also evaluated the results. The proposed algorithms are tested on a set of more than 1000 selected frame samples from the entire 39 testing videos, to a prevalence of 50% pathologic frames (balanced dataset). The frame elimination of identical and consecutive frames achieved a reduction of 36% of total frames. The best statistical performance for diagnosis of positive pathological frames from a video stream is achieved by utilizing masks in the HSV color model, with sensitivity up to 99%, precision 94.41% to a prevalence of 50%, accuracy up to 96.1%, FNR 1%, FPR 6.8%. The estimated blood-color chart will be clinically validated and used in feature extraction schemes supporting machine learning ML algorithms to improve the localization potential.

关键词： Capsule Endoscopy small bowel bleeding detection Computer Aided Diagnosis (CAD) Color Models Color Feature

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