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Congenital tuberculosis with tuberculous meningitis and situs inversus totalis:A case report

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World Journal of Clinical Cases 2022年第16期10卷 5495-5501页

作者： Hu Lin Shuang Teng Zhong Wang Qi-Yu Liu Department of Radiology The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Clinical Medicine Chengdu University of Traditional Chinese MedicineChengdu 610036Sichuan ProvinceChina Department of Radiology Mianyang Central HospitalMianyang 621000Sichuan ProvinceChina

BACKGROUND Congenital tuberculosis(TB),tuberculous meningitis,and situs inversus totalis are rare *** here report a patient who simultaneously suffered from these three rare *** is currently no such report in the *** TB is easily misdiagnosed and has a high case fatality *** anti-TB treatment is *** SUMMARY A 19-day-old male newborn was admitted to hospital due to a fever for 6 *** blood tests and chest X-rays suggested infection,and he was initially considered to have neonatal pneumonia and *** did not respond to conventional antiinfective ***,Mycobacterium tuberculosis was found in sputum lavage fluid on the 10th day after *** addition,the mother's tuberculin skin test was positive,with an induration of 22 mm,and her pelvic computed tomography scan suggested the possibility of tuberculous pelvic inflammatory *** child was diagnosed with congenital TB and immediately managed with anti-TB therapy and symptomatic supportive ***,the infant's condition gradually worsened and he developed severe tuberculous pneumonia and tuberculous meningitis,and eventually died of respiratory *** If conventional anti-infective treatment is ineffective in neonatal pneumonia,anti-TB treatment should be considered.

关键词： Tuberculosis Congenital situs inversus Newborn Infant Case report

Laparoscopic common bile duct exploration to treat choledocholithiasis in situs inversus patients:A technical review

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World Journal of Clinical Cases 2023年第9期11卷 1939-1950页

作者： Bo-Ya Chiu Shu-Hung Chuang Shih-Chang Chuang Kung-Kai Kuo School of Post-baccalaureate Medicine College of MedicineKaohsiung Medical UniversityKaohsiung 80708Taiwan Division of General and Digestive Surgery Department of SurgeryKaohsiung Medical University HospitalKaohsiung Medical UniversityKaohsiung 80708Taiwan School of Medicine College of MedicineKaohsiung Medical UniversityKaohsiung 80708Taiwan

situs inversus(SI)is a rare congenital condition characterized by a mirror-image transposition of the major visceral *** the 1990s,more than one hundred SI patients have been reported to have successfully undergone laparoscopic *** these cases,the major problem is to overcome is the left-right condition for right-handed *** common bile duct exploration(LCBDE),an alternative to treat patients with bile duct stones,has shown equivalent efficacy and is less likely to cause pancreatitis than endoscopic retrograde *** updated meta-analyses revealed that a shorter postoperative hospital stay,fewer procedural interventions,cost-effectiveness,a higher stone clearance rate,and fewer perioperative complications are additional advantages of ***,the technique is technically demanding,even for skilled laparoscopic *** LCBDE in patients with difficult situations,such as SI,is more complex than *** herein review published SI patients with choledocholithiasis treated by LCBDE,including our own experience,and this paper focuses on the technical aspects.

关键词： Choledocholithiasis Choledochotomy Laparoscopic common bile duct exploration Single incision situs inversus Transcystic

Percutaneous Closure of Patent Foramen Ovale in a Patient with Mirror-Image Dextrocardia and situs inversus

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Cardiovascular Innovations and Applications 2020年第3期16卷 63-66页

作者： Xiaofei Jiang Heng Zhang Mingyang Qian Cardiology Department Zhuhai People’s Hospital(Zhuhai Hospital Affi liated with Jinan University)79th Kangning RoadXiangzhou DistrictZhuhai519000 GuangdongChina Ultrasonography Department Zhuhai People’s Hospital(Zhuhai Hospital Affi liated with Jinan University)79th Kangning RoadXiangzhou DistrictZhuhai519000 GuangdongChina Pediatric Cardiology Department Guangdong Cardiovascular Institute96th Dongchuan RoadYuexiu DistrictGuangzhou510080 GuangdongChina

A 26-year-old patient with mirror-image dextrocardia and situs inversus experienced a transient ischemic *** suspected that a patent foramen ovale was the reason.A Cardi-O-Fix occluder was used to close the patent foramen ovale with a mirror-reversed rotation of the radiologic *** the 18-month follow-up,no symptoms of the transient ischemic attack appeared again.

关键词： patent foramen ovale situs inversus mirror-image dextrocardia digital subtraction angiography

situs inversus: A Review of 191 Published Cases

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Open Journal of Internal Medicine 2022年第2期12卷 85-94页

作者： John Osaretin Osarenkhoe Igbinedion University Teaching Hospital Okada Nigeria

Background: situs inversus is a rare congenital disorder that causes a reversal in the anatomical arrangement of chest and abdominal organs, such that the organs are mirror images of the normal anatomy. It is generally classified into three: situs inversus totalis, situs abdominis (with levocardia), and situs ambiguous. Although many patients with situs inversus do go on to live normal uneventful lives, several cardiovascular, gastrointestinal as well multisystemic comorbidities have been shown to be associated with the condition. The aim of the study is to analyse and give an overview of the proportion of the different types of situs inversus and the common major comorbidities at presentation (both acquired and congenital) including the age and sex predilection, as well as the proportion of the different diagnostic methods for situs inversus. Method: Published cases from English medical journals were evaluated and analysed. Results: 191 published cases on situs inversus were reviewed. situs inversus totalis had the highest proportion (82.7%) compared to situs ambiguous (13.6%) and situs inversus abdominis (with levocardia) (3.7%). There was no sex predilection, with a male to female ratio of 0.96 (P = 0.83). According to our study, the commonest comorbidity patients with situs inversus presented with were cholelithiasis (13.6%) and Kartagener syndrome (9.4%). Presenting comorbidities with digestive system affectation had the highest proportion (57.1%). Conclusion: The study established a significant association between acquired digestive system comorbidities like cholelithiasis, compared to other comorbidities.

关键词： situs inversus Dextrocardia Comorbidity

Classical orthotopic liver transplantation from a donor with situs inversus totalis using slight rotation of the liver graft

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Chinese Medical Journal 2010年第10期123卷 1353-1355页

作者： DOU Jian YANG Tao CAO Jing-lin GAO Qing-jun SU Yan-ling ZHU Zhi-jun Department of Hepatobiliary Surgery the Third Hospital of Hebei Medical University Shijiazhuang Hebei 050051 China Department of Orthopedics the Third Hospital of Hebei Medical University Shijiazhuang Hebei 050051 China Department of Transplantation Tianjin First Center Hospital Tianjin 300192 China

situs inversus totalis （SIT） is a rare congenital abnormality that affects approximately 0.005% of all live births. 1 Liver grafts with SIT have traditionally been considered as an absolute contraindication for transplant because of anatomical concerns.2 A review of the literature indicated that there were only four cases of liver transplantation using an SIT donor and normal recipient.3-6 Various modified ＂piggyback＂ techniques were used in all of these cases. In the present case, we obtained a liver from a deceased donor with SIT,

关键词： situs inversus liver transplantation tissue donors

Liver transplantation in a patient with situs inversus:a case report

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Chinese Medical Journal 2007年第15期120卷 1376-1377页

作者： WEI Jun-ming LIU Yan-nan QIAO Jiang-chun WU Wei-ran Department of General Surgery Beijing Hospital Beijing 100730 China

situs inversus （SI） is a congenital anomaly characterized by the mirror-image orientation of the inner organs. The estimated incidence of SI is 1/15 000 to 1/10 000 live births. The disease is often complicated with biliary atresia, polysplenia, intestinal nonrotation, preduodenal portal vein, aberrant hepatic artery, or absence of the suprarenal inferior vena cava. In 2004, we performed a liver transplantation on a patient with SI complicated with hepatolithiasis, end-stage liver cirrhosis and liver failure, because of the unavailability of donor organs, the operation became more complicated and difficult.

关键词： situs inversus orthotopic liver transplantation hepatolithiasis

Liver Transplantation in a Patient with situs inversus Associated with Biliary Atresia, Polysplenia and Absence of Inferior Vena Cava: A Case Report

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Surgical Science 2016年第2期7卷 89-95页

作者： Henrique de Aguiar Wiederkehr Caroline Aragão de Carvalho Matheus Ruggeri Lucca Cajazeira Campos Barbara de Aguiar Wiederkehr Julio Cesar Wiederkehr School of Medicine Faculdade Evangélica do Paraná (FEPAR) Curitiba Brazil Department of Surgery Federal University (UFPR) Curitiba Brazil

Biliary atresia (BA) is the result of a process of unknown etiology which can occur as an isolated lesion or in association with several congenital abnormalities and remains the main indications of liver transplantation among infants. One of the malformations associated with biliary atresia is situs inversus totalis, which is a rare congenital abnormality found in 10% - 20% of infants with biliary atresia and presents an incidence varying from 1:5000 to 1:20,000. This case report aims to present an extremely rare case of a patient with situs inversus associated with biliary atresia, polysplenia and abscence of inferior vena cava that underwent liver transplantation. Case Report: A 10-month-old boy was referred to our hospital with the diagnosis of cirrhosis, due to biliary atresia. Abdominal ultrasound and Doppler scan showed the liver in the left upper quadrant as well as signs of chronic liver disease. In addition, we could notice that the spleen had several lobes, suggesting polysplenia, and was positioned in the right upper quadrant. The patient underwent living donor liver transplant. His mother was the donor and the graft, segment III, was positioned in the left upper quadrant associated with a Y en Roux reconstruction of the biliary tract. During the first post-operatory day, the patient presented signs of disseminated sepsis. Laboratory and imaging diagnostic tests were performed presenting a small intestinal malrotation associated with diffuse ischemia. The patient died at the third day of PO due to complications related to this condition. Conclusion: Any patient with situs inversus with acute abdomen should be aggressively investigated for other structural and biochemical abnormalities. If liver transplant is indicated, the procedure can be successfully performed.

关键词： Liver Transplantation situs inversus Polysplenia Biliary Atresia

Incomplete situs inversus Revealed by Acute Pain of the Right Hypochondrium

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Open Journal of Gastroenterology 2022年第10期12卷 263-270页

作者： Alice Nanelin Guingané Julien Sawadogo Adjirata Koama Bénilde Marie-Ange Tiemtoré-Kambou Roger Sombié Alain Bougouma Service d’hépato-gastroentérologie CHU Bogodogo Ouagadougou Burkina Faso Service de chirurgie générale et digestive du CHU-YO Ouagadougou Burkina Faso Service de radiologie CHU Bogodogo Ouagadougou Burkina Faso Service d’hépato-gastroentérologie CHU-YO Ouagadougou Burkina Faso

situs inversus is an abnormal placement of the thoracic and/or abdominal organs that are inverted right/left from normal. It is a rare congenital malformation often discovered in childhood. In adults, it can lead to misdiagnosis. Clinical case: A 35-year-old female patient, seen in a hepatogastroenterology consultation for acute spontaneous pain in the right hypochondrium. She had no particular clinical history. A diagnosis of hepatopathy was suspected. Abdominal and pelvic CT scans showed the left liver, stomach and spleen in the right hypochondrium, but with the heart in place, suggesting incomplete situs inversus. The evolution in our patient was spontaneously resolved with analgesics and antispasmodics, which leads us to believe that the volvulus was probably partial and without other complications. Conclusion: In developing countries, antenatal diagnosis of situs inversus is rare and is usually made during a pathology that leads the patient to a medical consultation. CT is one of the key paraclinical examinations for its diagnosis as genetic tests are not widely available.

关键词： situs inversus Abdominal Pain Hypochondrium Abdominal CT Scan

Successful Transcatheter Closure of Patent Ductus Arteriosus in Isolated Levocardia with situs inversus

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World Journal of Cardiovascular Diseases 2016年第4期6卷 88-93页

作者： Adikesava Naidu Otikunta Y. V. Subba Reddy Sivaprasad Naidu Nallapati S. A. A. Latheef Srinivas Ravi Department of Cardiology Osmania General Hospital & Osmania Medical College Hyderabad India School of Life Sciences University of Hyderabad Hyderabad India

Isolated levocardia with situs inversus is an extremely rare type of situs anomaly with an estimated incidence of 1 per 22,000 in the general population. This autosomal recessive situs anomaly has been described as normal levo position of the heart with dextro position of the abdominal viscera. In this case report, we describe accidental diagnosis of isolated levocardia with situs inversus in pediatric patient while evaluating for heart murmur. Systematic examination of the patient identified the presence of patent ductus arteriosus, anomalous course of inferior vena cava and bovine aortic arch. We shared our experience of successful transcatheter closure of patent ductus arteriosus. This case report is worth reporting both, for demonstrating the possibility of the percutaneous device closure of the patent ductus arteriosus in patient with this unusual situs anomaly to interventional cardiologists and because of scanty of literature.

关键词： situs inversus Isolated Levocardia Patent Ductus Artrious Transcatheter Closure Anomalous Inferior Vena Cava Bovine Aortic Arch