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Current therapeutic strategies for premature ejaculation and future perspectives

Asian Journal of Andrology 2011年第4期13卷 550-557页

作者： Zhong-Cheng Xin Yi-Chen Zhu Yi-Ming Yuan Wan-Shou Cui Zhe Jin Wei-Ren Li Tao Liu Andrology Centre of Peking University First Hospital Peking University Beijing 100034 China Department of Urology Beijing Friendship Hospital Capital Medica University Beijing 100050 China

Premature ejaculation （PE） is a common sexual disorder in men that is mediated by disturbances in the peripheral and central nervous systems. Although all pharmaceutical treatments for PE are currently used ＇off-label＇, some novel oral agents and some newer methods of drug administration now provide important relief to PE patients. However, the aetiology of this condition has still not been unified, primarily because of the lack of a standard animal model for basic research and the absence of a widely accepted definition and assessment tool for evidence-based clinical studies in patients with PE. In this review, we focus on the current therapeutic strategies and future treatment perspectives for PE.

关键词： 5-HT dapoxetine premature ejaculation sexual disorder selective serotonin reuptake inhibitor treatment

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Erectile Dysfunction (ED) within Hospital Facilities in Cotonou

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Open Journal of Urology 2017年第3期7卷 65-74页

作者： Natchagande Gilles Avakoudjo Dedjinin Georges Josue Yevi Ines Dodji Magloire Agounkpe Michel Michael Kaka Mahamane Adama Salissou Sossa Jean Hodonou DetondjiFred Jacquet Djamal Soumanou Fouad Hounnasso Prince Pascal CNHU-HKM Urology-Andrology University Clinic CotonouRepublique of Benin

Introduction: Erectile dysfunction (ED) is defined as the persistent inability to achieve the necessary degree of erection for sexual activity. It is a common disease which can significantly affect the quality of life of sufferer and their partners. The purpose of this study is to give an overview of the magnitude of this medical condition in Benin society. Material and Method: It was a multicenter cross-sectional descriptive and analytical study conducted over a period of one month from 1st to 30th June 2015. A questionnaire was prepared for this purpose. Outcomes: The average age in this series is 48.32 with extremes ranging from 18 to 95 years. These patients were predominantly public servants. All our patients (100% of the study population) responded to the single question of John. B. Mckinlay. The global ED prevalence was 52.6%. The multivariate analysis helped to identify a correlation with several factors associated with ED. These factors included: age, occupation, lifestyle, etc. 41.91% of patients with ED and/or other sexual disorders declared “not at all acceptable” to continue living with these disorders. The patients benefitted from different treatments including IPDE-5 and traditional treatment in respectively 32.8% and 40.1% of cases. Conclusion: ED is a condition in its own which has an impact on the patients’ quality of life. Its discovery may lead to the diagnosis of cardiovascular, hormonal or neurological diseases.

关键词： ED sexual disorder sexuality

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