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An early scoring system to predict mechanical ventilation for botulism: a single-center-based study

World Journal of Emergency Medicine 2024年第5期15卷 365-371页

作者： Yaqing An Tuokang Zheng Yanling Dong Yang Wu Yu Gong Yu Ma Hao Xiao Hengbo Gao Yingping Tian Dongqi Yao Emergency Department the Second Hospital of Hebei Medical UniversityShijiazhuang 050051China

BACKGROUND:Early identifi cation of patients requiring ventilator support will be benefi cial for the outcomes of *** present study aimed to establish a new scoring system to predict mechanical ventilation(MV)for botulism ***:A single-center retrospective study was conducted to identify risk factors associated with MV in botulism patients from 2007 to *** analysis and multivariate logistic regression analysis were used to screen out risk factors for constructing a prognostic scoring *** area under the receiver operating characteristic(ROC)curve was ***:A total of 153 patients with botulism(66 males and 87 females,with an average age of 43 years)were *** these,49 patients(32.0%)required MV,including 21(13.7%)with invasive ventilation and 28(18.3%)with non-invasive *** analysis revealed that botulinum toxin type,pneumonia,incubation period,degree of hypoxia,and severity of muscle involvement were independent risk factors for *** risk factors were incorporated into a multivariate logistic regression analysis to establish a prognostic scoring *** risk factor was scored by allocating a weight based on its regression coeffi cient and rounded to whole numbers for practical utilization([botulinum toxin type A:1],[pneumonia:2],[incubation period≤1 day:2],[hypoxiaseverity of muscle involvement:grade II,3;grade III,7;grade IV,11]).The scoring system achieved an area under the ROC curve of 0.82(95%CI 0.75-0.89,Pseverity of muscle involvement as independent risk factors for MV in botulism patients.A score≥9 in our scoring system is associated with a higher likelihood of requiring MV in botulism *** scoring system needs to be validated externally bef

关键词： Botulism Scoring system Botulinum toxin type Incubation period Hypoxia Pneumonia severity of muscle involvement

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