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Biomedical and Environmental Sciences 2014年第7期27卷 495-505页

作者： SUN Bao Qing CHEN De Hui ZHENG Pei Yan HUANG Hui Min LUO Wen Ting ZENG Guang Qiao ZHANG Xiao Wen State Key Laboratory of Respiratory Disease National Clinical Center for Respiratory DiseasesGuangzhou Institute of Respiratory DiseasesFirst Affiliated HospitalGuangzhou Medical University Department of Pediatrics First Affiliated HospitalGuangzhou Medical University Department of Otorhinolaryngology-Head & Neck Surgery First Affiliated HospitalGuangzhou Medical University

Objective To investigate the serum total ige （tlgE） and specific ige （slgE） to common allergens among allergic patients in Guangzhou, China. Methods 7 085 patients were examined for tlgE and slgE to 15 allergens, based on the protocols of reversed enzyme allergosorbent test and the sandwich enzyme-linked immunosorbent assay. Results 3 758 （53.04%） patients tested positive for tlgE, and 4 640 （65.49%） for slgE. Der pteronyssinus, Derfarinae, eggs, and cow＇s milk were the most common allergens leading to higher positive rates of slgE responses. Several peaks of sensitization were： Der pteronyssinus, Derfarinae, and Blomia tropicalis at age 10-12; cow＇s milk at age below 3; eggs at age 4-6. The mean level and positive rate of tlgE tended to increase in subjects sensitized to more allergens. Sensitization to Der pteronyssinus （OR, 1.6; P〈O.05）, Der farinae （OR, 1.5; P〈O.05）, Blomia tropicalis （OR, 1.4; P〈O.05）, Blattella germanica （OR, 1.5; P〈O.05）, cow＇s milk （OR, 1.3; P〈O.05）, and soy beans （OR, 2.0; P〈O.05） were independently correlated with allergy-related conditions in preliminary diagnosis. Conclusion The major allergens in Guangzhou include Derpteronyssinus, Derfarinae, cow＇s milk, and eggs. Sensitization to these allergens appears to be predictors of allergy-related disorder.

关键词： Allergy Allergen Symptoms serum ige

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Treatment of “itching symptom” of allergic rhinitis from the perspective of “wind”

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World Journal of Acupuncture-Moxibustion 2017年第4期27卷 60-64页

作者：冯罡鹤壁京立医院康复科河南458030

Objective To observe the clinical efficacy of ＂itching symptom＂ of allergic rhinitis treated from the perspective of ＂wind＂. Methods Forty patients were given acupuncture therapy, Fengchf （风池 GB 20, bilaterally）, Dazhui （大椎 GV 14）, Fengmen （风门 BL 12, bilaterally）, Feishu （肺俞 BL 13, bilaterally） and Shangyingxiang （上迎香 EX-HN8, bilaterally） were selected. After needle withdrawal, a fire cup was applied between GV 14 and BL 13, and the cup was retained for 10 min. Treatment for 15 times was considered as 1 course of treatment. Three days were free from treatment between 2 courses, and 3 courses were needed. The curative effect was evaluated after treatment ends, and follow-up visit was performed one year after treatment. Results The scores of nasal symptom and itching symptom after treatment ends and one year after treatment significantly reduced when compared with that before treatment （all P〈0.05）, the difference was not statistically significant when compared the scores of nasal symptom and itching symptom one year after treatment with that after treatment ends （both P〉O.O5）.According to the follow-up visit performed one year after treatment, the markedly effective and effective cases reduced, ineffective cases increased, and the total effective rate declined slightly. The serum ige levels, after treatment ends I-（164.79±44.29） IU/mL and one year after treatment [（180.71±52.81）IU/ mL] , both significantly reduced when compared with that before treatment [（380.12±61.45） IU/mL, both P〈0.05] , the serum ige level one year after treatment increased when compared with that after treatment ends, but the difference was not statistically significant （P〉O.05）. Conclusion （1） Significant short-term and long-term curative effects have been obtained during the treatment of ＂itching symptom＂ of allergic rhinitis from the perspective of ＂wind＂, （2） the mechanism of action may be related with the decrease of serum ige level, （3） it is indicated that there are correlations betwee

关键词： allergic rhinitis itching symptom wind-evil serum ige

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Clinical Observation of Zhuang Medicine Crystal Sugar Ye'An Decoction in Treating Senile Skin Pruritus and Its Effects on serum lgE

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Journal of Clinical and Nursing Research 2020年第6期4卷 79-83页

作者： Yun Zhang Yuying Lan Guangxi University of Chinese Medicine Nanning City 530001Guangxi ProvinceChina

Objective:To discuss the specific application of Zhuang Medicine Crystal Sugar Ye'An Decoction in senile skin pruritus and its effects on serum ige detection ***:90 patients with senile skin pruritus admitted to our hospital from February 2019 to April 2020 were randomly *** general treatment effect,itching,secondary skin lesion severity,sernum IL-6,ige level and adverse reactions between 45 patients treated with Chlorcyclizine Hydrochloride Tablets(The control group)and 45 patients treated with Crystal Sugar Ye'An Decoction were ***:The total effective rate of the treatment in the observation group was 93.33%,much higher than that in the control group,75.56%.The difference was verified and statistically significant(P0.05).After the treatment,the above data were all reduced,and the reduction of the observation group was more significant than that of the control group,indicating the difference was statistically significant(Pserum IL-6 and ige test data between the two groups(P>0.05).After the treatment,the tendency all declined,and that of the observation group was more obvious,indicating the difference was statistically significant(P<0.05).During the experiment,no obvious adverse reactions were observed in both ***:In the treatment of patients with senile pruritus,the application of Zhuang Medicine Crystal Sugar Ye’An Decoction is not only safe and reliable,but can promote the improvement of patients'symptoms,adjust the level of inflammatory factors,and enhance clinical efficacy.

关键词： Zhuang medicine Senile skin pruritus serum ige Crystal Sugar Ye An Decoction

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