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The application of indocyanine green in guiding prostate cancer treatment

Asian Journal of Urology 2023年第1期10卷 1-8页

作者： Donghua Xie Di Gu Ming Lei Cong Cai Wen Zhong Defeng Qi Wenqi Wu Guohua Zeng Yongda Liu Department of Urology Minimally Invasive Surgery CenterThe First Affiliated Hospital of Guangzhou Medical UniversityGuangdong Key Laboratory of UrologyGuangzhouChina

Objective:Indocyanine green(ICG)with near-infrared fluorescence absorption is approved by the United States Food and Drug Administration for clinical applications in angiography,blood flow evaluation,and liver function *** has strong optical absorption in the near-infrared region,where light can penetrate deepest into biological *** sought to review its value in guiding prostate cancer ***:All related literature at PubMed from January 2000 to December 2020 were ***:Multiple preclinical studies have demonstrated the usefulness of ICG in identifying prostate cancer by using different engineering *** studies have demonstrated the usefulness of ICG in guiding sentinel node dissection during radical prostatectomy,and possible better preservation of neurovascular bundle by identifying landmark prostatic *** techniques such as adding fluorescein in additional to ICG were tested in a limited number of patients with encouraging *** addition,the use of the ICG was shown to be *** though there are encouraging results,it does not carry sufficient sensitivity and specificity in replacing extended pelvic lymph node dissection during radical ***:Multiple preclinical and clinical studies have shown the usefulness of ICG in identifying and guiding treatment for prostate *** randomized prospective studies are warranted to further test its usefulness and find new modified approaches.

关键词： Indocyanine green Intraoperative imaging Prostate cancer sentinel lymph node dissection Neurovascular bundle

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