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检索条件"主题词=Self-activating"
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Intracellular effects of prodrug-like wortmannin probes
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Chinese Chemical Letters 2019年 第1期30卷 67-70页
作者: Shasha Ying Shubo Du Jia Dong Bi Xuan Ng Chengwu Zhang Lin Li Jingyan Ge Qing Zhua Key Laboratory of Bioorganic Synthesis of Zhejiang Province College of Biotechnology and Bioengineering Zhejiang University of Technology Department of Chemistry National University of Singapore Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing Tech University (Nanjing Tech)
Wortmannin, a known inhibitor of phosphoinositide 3-kinases(PI3 Ks), their low selectivity and high toxicity is still problematic and less is known about their effects on PI3 Ks in cellular systems. Hence, we have syn... 详细信息
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