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Liver transplantation as an alternative for the treatment of neuroendocrine liver metastasis: Appraisal of the current evidence

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 146-153页

作者： Philip C.Muller Matthias Pfister Dilmurodjon Eshmuminov Kuno Lehmann Department of Surgery and Transplantation University Hospital ZurichRämistrasse 100Zurich CH-8091Switzerland

Background:Liver transplantation(LT)for neuroendocrine liver metastases(NELM)is still in debate.Studies comparing LT with liver resection(LR)for NELM are scarce,as patient selection is heterogeneous and experience is limited.The goal of this review was to provide a critical analysis of the evidence on LT versus LR in the treatment of NELM.Data sources:A scoping literature search on LT and LR for NELM was performed with PubMed,including English articles up to March 2023.Results:International guidelines recommend LR for NELM in resectable,well-differentiated tumors in the absence of extrahepatic metastatic disease with superior results of LR compared to systemic or liver-directed therapies.Advanced liver surgery has extended resectability criteria whilst entailing increased perioperative risk and short disease-free survival.In highly selected patients(based on the Milan criteria)with unresectable NELM,oncologic results of LT are promising.Prognostic factors include tumor biology(G1/G2)and burden,waiting time for LT,patient age and extrahepatic spread.Based on low-level evi-dence,LT for low-grade NELM within the Milan criteria resulted in improved disease-free survival and overall survival compared to LR.The benefits of LT were lost in patients beyond the Milan NELM-criteria.Conclusions:With adherence to strict selection criteria especially tumor biology,LT for NELM is becoming a valuable option providing oncologic benefits compared to LR.Recent evidence suggests even stricter selection criteria with regard to tumor biology.

关键词： Liver transplantation Neuroendocrine liver metastases Liver resection selection criteria Tumor biology

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Ordinary Urban Heritage of Rattanakosin: Ordinary restaurants and everyday foods of the historic center of Bangkok

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Frontiers of Architectural Research 2024年第2期13卷 335-348页

作者： Prin Jhearmaneechotechai Design for Creative Economy Research Unit Department of Urban and Regional PlanningFaculty of ArchitectureChulalongkorn UniversityBangkok 10330Thailand

This paper discussed the selection criteria for Ordinary Urban Heritage (OUH) in Rattanakosin, the historic center of Bangkok through the case of ordinary restaurants and everyday foods. The OUH stands for an alternative approach to heritage understanding and conservation, derived from the notion of ordinary heritage, vernacular heritage, and urban heritage emphasizing the heritages of the everydayness of ordinary people. The OUHs have co-existed and inherited through the evolution of the city but are overlooked by the official conservation process. Ordinary restaurants and everyday foods were selected by 5 criteria, 1) appeared for more than 50 years;2) created, developed, and used by ordinary people;3) found as the clusters;4) able to be adapted to the urban context;5) exist until the present day.The methodology applied to the analysis of the historical documents and Bangkok maps from 1887 to 1974, and the selection criteria developed from past research in another old commercial district of Bangkok were also reinvestigated with observational surveys. Ordinary restaurants and everyday foods are the outcomes representing the heritage of everyday life of ordinary people that are ubiquitously related to commercial activities.

关键词： Ordinary restaurants Everyday foods Rattanakosin selection criteria Ordinary Urban Heritage

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A preliminary study on criteria weights for a library's digital resource selection:From the viewpoints of both users and librarians

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Chinese Journal of Library and Information Science 2011年第Z1期4卷 82-96页

作者： Qiong TANG Gang WU Danni LIANG Yingliang ZHANG Mingjun TAN School of Information Management Sun Yat-sen University School of Information Management Wuhan University Wuhan University Library

Through investigating both users' and librarians' perceptions of the relative importance of the major criteria governing the selection of digital resources, we attempted to develop a criterion weight framework for a library's selection of digital resources, which can meet both the users' requirements and the library's goal of developing digital collections. The respective weight of each specific criterion is decided through the Analytic Hierarchy Process(AHP) Method. The findings of this study indicate that, when assigning weights to the selection criteria, it is important to consult the opinions of a wide crosssection of people, especially the views of different users. As a result, the digital resource selection system characterized by the criteria weights can reflect more comprehensively the users' requirements, and meanwhile it enables librarians' more rational selection of digital resources.

关键词： Library digital resources selection criteria criteria weights Analytic Hierarchy Process(AHP)

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Redox Mediator Chemistry Regulated Aqueous Batteries:Insights into Mechanisms and Prospects

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CCS Chemistry 2022年第9期4卷 2874-2887页

作者： Tengsheng Zhang Qianru Chen Xinran Li Jiahao Liu Wanhai Zhou Boya Wang Zaiwang Zhao Wei Li Dongliang Chao Dongyuan Zhao Laboratory of Advanced Materials Shanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsSchool of Chemistry and MaterialsFudan UniversityShanghai 200433

Redox mediators(RMs),serving as intermediate electron carriers or reservoirs,play vital roles in developing new charge transfer energy storage systems with high voltage or capacity in aqueous batteries.However,the underlying mechanism and selection criteria of RMs remain unclear in aqueous batteries,which hinders the further exploitation of new RMs and aqueous battery chemistries.

关键词： redox mediators aqueous batteries mechanism selection criteria high-efficiency highenergy

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Liver transplantation for malignant liver tumors

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iLIVER 2022年第1期1卷 3-11页

作者： Richard X.Sousa Da Silva Beat Muellhaupt Philipp Dutkowski Pierre-Alain Clavien Department of Surgery and Transplantation Swiss Hepato-Pancreato-Biliary(HPB)and Transplant CenterUniversity Hospital ZurichRaemistrasse 1008091 ZurichSwitzerland Wyss Zurich ETH ZurichUniversity of ZurichWeinbergstrasse 358006 ZurichSwitzerland Department of Gastroenterology and Hepatology University Hospital ZurichRaemistrasse 1008091 ZurichSwitzerland

Liver transplantation is a highly effective treatment not only for acute or chronic liver failure but also for primary liver cancer such as hepatocellular carcinoma,perihilar cholangiocarcinoma,intrahepatic cholangiocarcinoma,and metastatic tumors such as from neuroendocrine or colorectal liver metastases.The success strongly relies on strict adherence to stringent selection criteria,which lead to excellent outcomes,while previously regarded as contraindication for liver transplantation.These impressive results are,however,mostly achieved with a combination of pretreatment strategies and convincing control of the tumor growth prior to transplantation,as well as minimizing long-term immunosuppression.With this emergence of oncologic liver transplantation,we expect an increasing need of grafts,and therefore included in this report strategies to improve the number of available grafts by maximizing liver utilization rates.Modern machine liver perfusion approaches may play in this respect an important role.

关键词： Liver transplantation selection criteria Malignant tumor Machine perfusion Tumor recurrence

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Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

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Acta Pharmaceutica Sinica B 2021年第8期11卷 2505-2536页

作者： Sonal V.Bhujbal Biplob Mitra Uday Jain Yuchuan Gong Anjali Agrawal Shyam Karki Lynne S.Taylor Sumit Kumar Qi(Tony)Zhou Department of Industrial and Physical Pharmacy College of PharmacyPurdue University Oral Product Development Bristol Myers Squibb Material Science and Engineering Bristol Myers Squibb

Amorphous solid dispersions(ASDs)are popular for enhancing the solubility and bioavailability of poorly water-soluble drugs.Various approaches have been employed to produce ASDs and novel techniques are emerging.This review provides an updated overview of manufacturing techniques for preparing ASDs.As physical stability is a critical quality attribute for ASD,the impact of formulation,equipment,and process variables,together with the downstream processing on physical stability of ASDs have been discussed.selection strategies are proposed to identify suitable manufacturing methods,which may aid in the development of ASDs with satisfactory physical stability.

关键词： Amorphous solid dispersions Stability Drug delivery Manufacturing Solvent evaporation Melting process Co-precipitation Downstream processing selection criteria

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Selecting flagship species to solve a biodiversity conservation conundrum

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Plant Diversity 2020年第6期42卷 488-491页

作者： Jie Qian Huifu Zhuang Weikang Yang Yifeng Chen Shilong Chen Yanhua Qu Yuanming Zhang Yongping Yang Yuhua Wang Kunming Institute of Botany Chinese Academy of Sciences132 Lanhei RoadKunming650201YunnanChina Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences818 South Beijing RoadUrumqi830011XinjiangChina Northwest Institute of Plateau Biology Chinese Academy of Sciences23 Xinning RoadXining810008QinghaiChina Institute of Hydrobiology Chinese Academy of Sciences7 Donghu South RoadWuhan430072HubeiChina Institute of Zoology Chinese Academy of Sciences1 Beichen West RoadChaoyang DistrictBeijing100101China

The difficulty of effectively monitoring and managing the environment to conserve biodiversity is as yet an unsolved conundrum.A project of the Chinese Academy of Sciences has concluded that progress can be made through the use of flagship species selected using criteria drawn from conservation biology,ecosystem function,socio-economics,and cultural importance.Inclusion of the latter three criteria will help attract and maintain the commitment of the public to play full parts in carrying out any conservation measures needed.A system is proposed for scoring species to select those that are most suitable as flagships.This method can be used regardless of the size of the area chosen for attention,whether it is a region,a country,or a particular protected area.

关键词： Flagship species selection criteria Biodiversity conservation Proposed program

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Tree growth performance and estimation of wood quality in plantation trials for Maesopsis eminii and Shorea spp.

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Journal of Forestry Research 2018年第4期29卷 1144-1153页

作者： Lina Karlinasari Suhada Andini Descarlo Worabai Prijanto Pamungkas Sri Wilarso Budi Iskandar Z.Siregar Department of Forest Products Faculty of ForestryBogor Agricultural University(IPB) Alumnus Department of Silviculture Faculty of ForestryBogor Agricultural University(IPB) Department of Silviculture Faculty of ForestryBogor Agricultural University(IPB)

Plantations of tropical species axe becoming an increasingly important source of wood. However, it is important that research trials focus not only on tree growth performance, but also on wood quality. The aims of this study were to assess the growth performance of six commercially and ecologically important tree species from separate plantation trials in Indonesia and to determine the relationships between tree growth and wood quality in terms of the dynamic modulus of elasticity （MOE） and wood density. Forty-eight 7-year Maesopsis eminii Engl. and thirty-five 9-year specimens （7 each of 5 Shorea spp.） were selected from two trials. The MOE, based on acoustic velocity, was indirectly measured to evaluate wood stiffness. Tree-growth performance was evaluated, and correlations between growth traits and acoustic velocity as well as density and wood stiffness properties were estimated. The growth performance of M. eminii in terms of tree volume was significantly different in three different cate- gories of growth （i.e. fast, medium, slow）. Of the five Shorea spp. studied, Shorea leprosula Miq. had the highest growth rate, as expected since it is known to be a fastgrowing Shorea species. Indirect measurement of wood quality by means of non-destructive ultrasonic methods showed a weak negative correlation between tree volume and acoustic velocity and dynamic MOE. Although each fast-growing tree could reach a merchantable size faster than other varieties or species, wood traits of various species tested were not significantly different based on tree growth rate performance. The findings from this study could be used to improve selection criteria in future breeding trials; indirect measurements of the dynamic modulus of elasticity can be used in mass pre-selection of genetic materials, to choose the most-promising material for in-depth evaluation.

关键词： Dynamic MOE Non-destructive test selection criteria Tree growth Wood quality Maesopsiseminii Shorea spp

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Study on Breeding Practices and Reproductive Performance of Black-Head Somali Sheep under Traditional Management System: The Case of Awbarre District, Eastern Ethiopia

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Open Journal of Animal Sciences 2023年第1期13卷 20-33页

作者： Abdi Abdilahi Kawnin Abdimahad Abdulahi Mahamed Abdimawlid Ali Department of Animal and Range Sciences College of Dry Land Agriculture Jigjiga University Jigjiga Ethiopia Somali Region Pastoral and Agro-Pastoral Research Institute Jigjiga Ethiopia

The study was conducted in the Awbarre district of the Fafen zone of the Somali regional state of Ethiopia. The objective of the study was to assess the breeding practices and reproductive performance of Black-head Somali sheep under a traditional management system. Purposive and simple random sampling techniques were used to select targeted kebeles and households, respectively. A total of 120 households were selected from four kebeles, each of 30 households, based on the production system and sheep population. Semi-structured questionnaires, group discussions, key informants interviews and field observations were used to generate the required data. The primary purpose of keeping sheep was for income generation, followed by saving as a future asset. The majority (89.2%) of the respondents separated male and female animals during herding. The selection criteria for breeding rams were appearance, growth, pedigree, and color while for breeding ewes were appearance, adaptability, pedigree, color, and lamb growth. The overall weaning age of Black-head Somali sheep in the study area was 3.7 months for both males & females. The castration of male sheep was common for the purpose of fattening, fattening with breeding control and breeding control as well. The castration is mainly performed during the summer and autumn and the methods of castration were both traditional and modern methods, the traditional castration method being the most important one in pastoral areas. The age of sexual maturity was 7.64 months for rams and 8.97 months for ewe’s male and female lambs in the pastoral area and 8.42 & 8.38 for rams & ewes in agro-pastoral and overall lambing interval was 11 months. On average, the ewe of Black-head Somali sheep in pastoral & agro-pastoral could produce 9.49 & 9.57 lambs, respectively in their lifetime. As the pastoralists and agro-pastoralists indicated the source of the breeding ram was their own, so the exchange of breeding ram is recommended to minimize the risk of inbreeding and further studies of on-far

关键词： Black-Head Somali Sheep Breeding Practice Reproductive Performance selection criteria

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Screening Methods for Waterlogging Tolerance at Maize (Zea mays L.) Seedling Stage

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Agricultural Sciences in China 2010年第3期9卷 362-369页

作者： LIU Yong-zhong, TANG Bin, ZHENG Yong-lian, MA Ke-jun, XU Shang-zhong and QIU Fa-zhan National Key Laboratory of Crop Genetic Improvement/Huazhong Agricultural University, Wuhan 430070, P.R.China National Key Laboratory of Crop Genetic Improvement/Huazhong Agricultural University Wuhan 430070 P.R.China

Waterlogging strongly affects agronomic performance of maize （Zea mays L.）. In order to investigate the suitable selection criteria of waterflooding tolerant genotypes, and identify the most susceptible stage and the best continuous treatment time to waterlogging, 20 common maize inbred lines were subjected to successive artificial waterflooding at seedling stage, and waterlogging tolerance coefficient （WTC） was used to screen waterflooding tolerant genotypes. In addition, peroxidase （POD） activities and malondialdehyde （MDA） contents were measured for 6 of 20 lines. The results showed that the second leaf stage （V2） was the most susceptible stage, and 6 d after waterflooding was the best continuous treatment time. Dry weight （DW） of both shoots and roots of all lines were significantly reduced at 6 d time-point of waterlogging, compared to control. POD activities and MDA contents were negatively and significantly correlated, and the correlation coefficient was -0.9686 （P 〈 0.0001）. According to the results, WTC of shoot DW can be used for practical screening as a suitable index, which is significantly different from control and waterlogged plants happened 6 d earlier. Furthermore, leaf chlorosis, MDA content and POD activities could also be used as reference index for material screening. The implications of the results for waterlogging-tolerant material screening and waterlogging-tolerant breeding have been discussed in maize.

关键词： maize （Zea mays L.） waterlogging tolerance screening method selection criteria

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