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3D bioprinting of collagen-based materials for oral medicine

Collagen and Leather 2024年第1期5卷 28-46页

作者： Bosen Yang Hai Liu Linli Jiang Yiwei Zeng Yiyuan Han Chuanlu Sha Xin Xie Hui Li Jiajing Zhou Wei Lin College of Biomass Science and Engineering Key Laboratory of Leather Chemistry and Engineering of Ministry of EducationNational Engineering Laboratory for Clean Technology of Leather ManufactureSichuan UniversityChengdu 610065China State Key Laboratory of Oral Diseases National Clinical Research Center for Oral DiseasesDepartment of Oral and Maxillofacial SurgeryWest China Hospital of StomatologySichuan UniversityChengdu 610065China Laboratory for Biomaterials and Drug Delivery Department of AnesthesiologyDivision of Critical Care MedicineBoston Children's HospitalHarvard Medical SchoolBostonMA 02115USA

Oral diseases have emerged as one of the leading public health challenges *** the existing clinical modalities for restoration of dental tissue loss and craniomaxillofacial injuries can achieve satisfactory therapeutic results,they cannot fully restore the original complex anatomical structure and physiological function of the tissue.3D printing of biological tissues has gained growing interest in the field of oral medicine with the ability to control the bioink component and printing structure for spatially heterogeneous repairing constructs,holding enormous promise for the precise treatment of oral ***,collagen-based materials have been recognized as promising biogenic bioinks for the regeneration of several tissues with high cell-activating and biocompatible *** this review,we summarize 3D printing methods for collagen-based biomaterials and their ***,we highlight the animal sources of collagen and their characteristics,as well as the methods of collagen ***,this review provides an overview of the 3D bioprinting technology for the regeneration of the pulpal nerve and blood vessels,cartilage,and periodontal *** envision that this technique opens up immense opportunities over the conventional ones,with high replicability and customized function,which can ultimately promote effective oral tissue regeneration.

关键词： 3D bioprinting Oral medicine Tissue engineering Collagen scaffold materials Bioink Hydrogel

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Selection of different endothelialization modes and different seed cells for tissue-engineered vascular graft

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Bioactive materials 2021年第8期6卷 2557-2568页

作者： Qingjin Cai Wanshan Liao Fangchao Xue Xiaochen Wang Weiming Zhou Yanzhao Li Wen Zeng Department of Cell Biology Third Military Medical UniversityChongqing400038China State Key Laboratory of Trauma Burn and Combined InjuryChongqingChina Departments of Neurology Southwest HospitalThird Military Medical UniversityChongqingChina

Tissue-engineered vascular grafts(TEVGs)have enormous potential for vascular replacement ***,thrombosis and intimal hyperplasia are important problems associated with TEVGs especially small diameter TEVGs(<6 mm)after *** of TEVGs is a key point to prevent ***,we discuss different types of endothelialization and different seed cells of tissue-engineered vascular ***,endothelial heterogeneity is also *** on it,we provide a new perspective for selecting suitable types of endothelialization and suitable seed cells to improve the long-term patency rate of tissue-engineered vascular grafts with different diameters and lengths.

关键词： Tissue-engineered vascular grafts scaffold materials seed cells vascular endothelialization endothelial heterogeneity

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The development of tissue engineering corneal scaffold:which one the history will choose?

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Annals of Eye Science 2018年第1期3卷 44-51页

作者： Lin Lin Xiuming Jin Eye Center Affiliated Second HospitalSchool of MedicineZhejiang UniversityHangzhou 310009China

Since the 21st century,the development of corneal tissue engineering technology has been developing *** the progress of biomaterials,cell culture and tissue engineering technology,tissue engineering cornea has gained great development in both basic scientific research and clinical *** particular,tissue engineered corneal scaffolds are the core components of tissue engineered *** is the focus of current research on tissue engineering cornea to search for scaffolds with good biocompatibility,high safety and good biomechanical *** this paper,the recent research progress of tissue engineering corneal materials is reviewed.

关键词： Tissue engineering cornea scaffold materials

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