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salvage surgery for nasopharyngeal cancer

World Journal of Otorhinolaryngology-Head and Neck surgery 2015年第1期1卷 -页

作者： Raymond K.Tsang William I.Wei Division of Otorhinolaryngology-Head and Neck surgery Department of Surgery University of Hong Kong Queen Mary Hospital Hong Kong Li ShuPui ENT Head & Neck surgery Centre Hong Kong Sanatorium & Hospital Hong Kong

Nasopharyngeal carcinoma (NPC) is a special type of head and neck cancer with a widely variable geographical variation in *** central location of the tumor inside the head coupled with the radiosensitivity of the tumor to radiation made radiation therapy the first choice in primary treatment of *** in radiotherapy and chemotherapy have markedly improved the local control of ***, a small but significant number of patients still suffered from loco-regional failures that would be amenable to *** form of retreatment was to employ a second course of *** efficacy of re-irradiation to treat local of regional recurrent NPC has been ***, the local tissue had already received a high dose of radiation and the second radiation could result in radiation toxicities to the local tissue, leading to significant *** salvage, on the other hand, could spare the patients from complications of *** to the difficult access of the nasopharynx, various surgical approaches had been devised for *** maxillary swing approach had the largest published experience with over 300 cases from various *** the recent decade, the endoscopic approach with or without robotic assistance had gained popularity for resecting small, centrally located *** minimally invasive approach further reduced the morbidity for treating locally recurrent *** recurrences had been a rare entity after the introduction of modern radiotherapy technique and concurrent *** of nodal failure with second radiation has dismal *** removal of the lymph node harboring the recurrence should be in the form of a formal radical neck *** cases of extensive nodal recurrence where microscopic disease may be present after a formal neck dissection, additional radiotherapy can be delivered with after-loading *** treatment played a defin

关键词： Nasopharyngeal carcinoma Nasopharyngectomy salvage surgery Recurrent cancer

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Inserting the Ulnar Prosthesis into Radius as a Novel salvage surgery for Revision Total Elbow Arthroplasty with Massive Bone Defect

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Chinese Medical Journal 2016年第16期129卷 1917-1921页

作者： Mao-Qi Gong Ji-Le Jiang Xie-Yuan Jiang Ye-Jun Zha Ting Li Department of Orthopedic Trauma Beijing Jishuitan Hospital Beijing 100035 China

Background： Infection and aseptic loosening are common complications of total elbow arthroplasty （TEA） and often require revision surgery. However, bone defects, along with other complications, bring an extra difficulty to the second surgery, especially for patients with a massive bone defect in the proximal ulna. Several methods including allograft or autograft have been introduced into practice, but none sufficiently solves these problems. Methods： We conducted a new surgical method for patients with a massive ulnar bone defect needing revision TEA. During revision arthroplasty, the ulnar prosthesis was inserted into the radius as a salvage procedure. Four consecutive patients received revision arthroplasty with this method between 2013 and 2016. Patients＇ data were collected to evaluate the clinical outcome. Results： All patients had a Grade Ill ulnar bone defect. At the last follow-up session, all patients reported a painless, functional elbow joint. Three patients suffered from a periprosthetic infection that was completely cured using the two-stage method. No major complications, including infection, aseptic loosening, or wound problems were found. One patient had a transient ulnar neuritis, and another had a transient radial neuritis. Both patients had full recovery at the last follow-up session. Conclusions： Inserting an ulnar prosthesis into the radius is a novel procedure for patients with a massive bone defect due to infection or aseptic loosening. It is a safe, quick, and effective treatment with a promising short-term outcome. This method should be provided as a salvage procedure for patients with a nonreconstructable ulnar bone defect.

关键词： Massive Bone Defect Prosthesis Radius Revision surgery salvage surgery Total Elbow Arthroplasty

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The role of salvage surgery in oral squamous cell carcinoma

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Plastic and Aesthetic Research 2016年第1期3卷 189-196页

作者： Raúl González-García Department of Oral and Maxillofacial-Head and Neck surgery University Hospital Infanta Cristina06080 BadajozSpain

Aim:To select and analyze the most representative papers published in the literature concerning oral squamous cell carcinoma(OSCC),specifically dealing with salvage surgery following primary treatment by surgery with or without by postoperative radiotherapy,specifically focusing in the oral cavity and oropharynx ***:A bibliography search on MEDLINE and EMBASE databases for studies published from March 2000 to March 2016 was *** authors only included studies published in the English language and those dealing with“squamous cell carcinoma of the oral cavity and/or oropharynx”.The following technical bibliographic exclusion criteria were applied:(1)case reports;(2)technical report;(3)animal or in vitro studies;(4)review articles;(5)uncontrolled clinical studies;and(6)publications in which the same data were published by the same group of *** abstracts of yielded results were reviewed and the full text of those with apparent relevance was ***:A total amount of 188 studies were found using the above reported searching *** original papers were finally selected according to the inclusion and exclusion *** 1,692 analyzed patients,overall recurrence rate was 26%(range:15-41.7%),with a mean 47.3%,35.1%and 10.9%local,regional and loco-regional recurrence,*** 5-year overall survival rate was 40.2%(range:37.5-42.9%).Conclusion:salvage surgery is the best option for the treatment of recurrent OSCC,either local,regional or loco-regional,with the highest rates in terms of survival and with an acceptable morbidity.

关键词： salvage surgery oral squamous cell carcinoma recurrent oral cancer

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Current indications for endoscopic submucosal dissection of early gastric cancer

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World Journal of Gastrointestinal Oncology 2021年第6期13卷 560-573页

作者： Zhi Zheng Jie Yin Xiao-Ye Liu Xiao-Sheng Yan Rui Xu Meng-Yi Li Jun Cai Guang-Yong Chen Jun Zhang Zhong-Tao Zhang Department of General surgery Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Department of Pathology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China

The development of endoscopic treatment technology has further promoted the minimally invasive treatment of early gastric cancer(EGC).Endoscopic treatment has achieved better therapeutic effects in terms of safety and prognosis and is the preferred treatment method for patients who meet the indications for endoscopic ***,the consequent problem is that some patients receiving endoscopic treatment may undergo non-curative resection,and the principle of follow-up management for non-curative resection patients deserves further *** addition,there are still debates on how to improve the accuracy of clinical staging,select a reasonable treatment method for patients who meet the expanded indications for endoscopic treatment,manage patients with positive endoscopic surgical margins,conduct research on function-preserving surgery,and manage the treatment of EGC under the current situation in ***,we aim to review current indications for endoscopic submucosal dissection of EGC in order to better inform treatment options.

关键词： Early gastric cancer Endoscopic submucosal dissection indications Noncurative resection salvage surgery Function-preserving surgery

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Intensive or not surveillance of patients with colorectal cancer after curative resection

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World Journal of Gastroenterology 2010年第12期16卷 1427-1429页

作者： Gerardo Rosati Medical Oncology Unit S.Carlo Hospital

It is common practice to follow patients with colorectal cancer for some years after resection and/or adjuvant *** are lacking about how often patients should be seen,what tests should be performed,and what surveillance strategy has a signifi cant impact on patient *** randomized trials have addressed this issue,but none had sufficient statistical *** published meta-analyses have established that overall survival is significantly improved for patients in the more intensive programs of *** improvement amounts to a risk difference of 7%(95% CI:3%-12%,P=0.002) in 5-year *** should be partly attributable to more frequent reoperation for cure of asymptomatic recurrence,or more intense follow-up,as well other factors,such increased psychosocial support and well-being,diet and lifestyle optimization,and/or improved treatment of coincidental diseases.A large-scale multicenter European study [Gruppo Italiano di Lavoro per la Diagnosi Anticipata(GILDA)] is underway to answer the question of what constitutes optimal surveillance for patients after primary therapy,based on an adequately powered study.

关键词： Colorectal cancer Follow-up Meta-analysis Recurrence salvage surgery

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游离股前外侧瓣在颊腮腺区巨大复合性缺损中的应用（英文）

游离股前外侧瓣在颊腮腺区巨大复合性缺损中的应用（英文）

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2020年全国口腔颌面-头颈肿瘤学术大会暨中华口腔医学会口腔颌面-头颈肿瘤专业委员会学术年会——创新超越、共赢未来

作者：汪延中山大学孙逸仙纪念医院

Purpose/Background:The aim of this study was to evaluate the outcomes of anterolateral thigh free flaps for the reconstruction of large buccal and parotid region defects in salvage surgery for elderly patients. Materials and Methods:This study evaluated 9 elderly patients(7 males and 2 females;average age=81.2 years) with large malignant tumors involving the buccal and parotid regions who underwent anterolateral thigh free flaps to reconstruct large buccal and parotid defects following radical resection.

关键词： salvage surgery buccal and parotid region defects anterolateral thigh free flap

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