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Predictive Ability of the SYNergy Between Percutaneous Coronary Intervention with TAXus and Cardiac Surgery score Ⅱ for Long-term Mortality in Patients with Three-vessel Coronary Artery Disease Undergoing Percutaneous Coronary Intervention Treated

引用

Chinese Medical Journal 2015年第16期128卷 2176-2182页

作者： Ji-Qiang He Xian-Peng Yu Cheng Peng Quan Li Ya-Wei Luo Yue-Chun Gao Xiao-Ling Zhang Chang-Yan Wu Hua Zhao Yu-Chen Zhang Jing-Hua Liu Shu-Zheng Lyu Fang Chen Department of Cardiology Beijing Anzhen Hospital Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease Beijing 100029 China

Background：The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery score Ⅱ （SS-Ⅱ） can well predict 4-year mortality in patients with complex coronary artery disease （CAD）,and guide decision-making between coronary artery bypass graft surgery and percutaneous coronary intervention （PCI）.However,there is lack of data regarding the utility of the SS-Ⅱ in patients with three-vessel CAD undergoing PCI treated with second-generation drug-eluting stents （DES）.The purpose of the present study was to evaluate the ability of the SS-Ⅱ to predict long-term mortality in patients with three-vessel CAD undergoing PCI with second-generation ***：Totally,573 consecutive patients with de novo three-vessel CAD who underwent PCI with second-generation DES were retrospectively *** to the tertiles of the SS-Ⅱ,the patients were divided into three groups：The lowest SS-Ⅱ tertile （SS-Ⅱ ≤20）,intermediate SS-Ⅱ tertile （SS-Ⅱ of 21-31）,and the highest SS-Ⅱ tertile （SS-Ⅱ ≥32）.The survival curves of the different groups were estimated by the Kaplan-Meier *** and multivariate Cox proportional hazard regression analyses were performed to evaluate the relationship between the SS-Ⅱ and 5-year *** performance of the SS-Ⅱ with respect to predicting the rate of mortality was studied by calculating the area under the receiver operator characteristic （ROC） *** predictive ability of the SS-Ⅱ for 5-year mortality was evaluated and compared with the SS ***：The overall SS-Ⅱ was 27.6 ± *** patients in the lowest,intermediate and the highest SS-Ⅱ tertiles,the 5-year rates of mortality were 1.6%,3.2%,and 8.6%,respectively （P =0.003）;the cardiac mortality rates were 0.5%,1.9%,and 5.2%,respectively （P =0.014）.By multivariable analysis,adjusting for the potential confounders,the SS-Ⅱ was an independent predictor of 5-year mortality （hazard ratio：2.45,95% confidence interval：1.38-4.36;P=0.002）.The SS-Ⅱ demonstrated a high

关键词： Mortality Percutaneous Coronary Intervention Predictive Ability Second-generation Drug-eluting Stents syntax score ii Three-vessel Coronary Artery Disease

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