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Clinical hematological and biochemical parameters in swiss,BALB/c,C57BL/6 and B6D2F1 Mus musculus

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Animal Models and Experimental Medicine 2020年第4期3卷 304-315页

作者： Giorgio Silva-Santana Juliet Cunha Bax Débora Cristina Silva Fernandes Daniela Tendler Leibel Bacellar Cleber Hooper Alexandre Alves Souza Oliveira Dias Cristina Barbosa Silva Aline Moreira de Souza Simone Ramos Ricardo Alexandre Santos Thainara Ramos Pinto Mariana Antunes Ramão Ana Luíza Mattos-Guaraldi Health Sciences Center Institute of Microbiology Paulo de GóesFederal University of Rio de JaneiroRio de JaneiroRJBrazil Laboratory of Diphtheria and Corynebacteria of Clinical Relevance Faculty of Medical SciencesUniversity of the State of Rio de JaneiroRio de JaneiroRJBrazil The Collaborating Centre for Reference and Research on Diphtheria/National Health Foundation/Ministry of Health Rio de JaneiroRJBrazil Laboratory of Clinical Research and Molecular Diagnostic Prof.Marcílio Dias do Nascimento Department of Clinical Practice and PathologyFluminense Federal UniversityNiteróiRJBrazil Laboratory Bacterial Vaccines Department of ImmunologyNational Institute for Quality Control in HealthOswaldo Cruz FoundationRio de JaneiroRJBrazil Institute of Science and Technology in Biomodels Oswaldo Cruz FoundationRio de JaneiroRJBrazil Institute of Biology Federal Fluminense UniversityNiteróiRJBrazil Biomedical Center College of Medical SciencesUniversity of the State of Rio de JaneiroRio de JaneiroRJBrazil

Background:Animal models are widely used in scientific research in order to obtain information from a whole organism under a specific set of experimental *** lineages of mice have been used to investigate diseases and new therapeutic strategies,and,consequently,hematological and biochemical tests in these laboratory animals are essential to validate scientific *** study seeks to establish reference values for hematological and biochemical parameters of four lineages of ***:We evaluated the hematological and biochemical profiles of 20 males and 20 females from the lineages swiss(heterogeneous),BALB/c and C57BL/6(isogenic),and B6D2F1(hybrid),totaling 160 *** were standardized using the systems pocH-100iV Diff™for 19 hematological parameters and VITROS®350 for 12 biochemical ***:Results are shown as means and standard deviation,grouped by lineage and *** the values obtained in this study with the values from previous studies,some variations were detected,which could be explained by differences in methodologies or individual ***:Thus our study shows that knowledge and disclosure of the values of physiological parameters of laboratory animals is necessary,and emphasises the importance of considering variations influenced by gender,lineage and genotype in the choice of the best experimental model.

关键词： B6D2F1 BALB/c biochemical C57BL/6 hematological swiss

Bioassay of Eucalyptus extracts for anticancer activity against Ehrlich ascites carcinoma(eac) cells in swiss albino mice

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Asian Pacific Journal of Tropical Biomedicine 2012年第5期2卷 394-398页

作者： Farhadul Islam Hasina Khatun Soby Ghosh MM Ali JA Khanam Department of Biochemistry and Molecular Biology Faculty of ScienceUniversity of Rajshahi Department of Applied Chemistry and Chemical engineering Faculty of EngineeringUniversity of Rajshahi

Objective:To evaluate the antineoplastic activity of Eucalyptus extract(EUE) against Ehrlich ascites carcinoma(EAC)in swiss albino ***:Preliminary examination of four plant extracts(namely Eucalyptus,Costus,*** has been done by observing the reduction ability of number of EAC cells in previously inoculated swiss alliino *** them as EuE showed maximum capability,the whole study has been conducted with EuE only. Important parameters *** of life span,reduction of average tumor weight *** been *** addition the effects of EuE on hematological parameters in both normal and EAC inoculated mice have been *** of EuE on normal peritoneal cells has also been ***:EuE reduced tumor burden *** reduced the tumor growth rate and enhanced the life span of EAC bearing mice *** reversed back the hematological parameters towards normal,reduced the Irasplanlability of EAC cells and enhanced the immunomodulatory effects in *** host toxic effect of EuE in mice is minimum and mostly reversible with *** such data have been compared with those obtained by running parallel experiments with bleomycin at dose 0.3 mg/kg(i.p.).Conclusions:The Eucalyptus extract may be considered as a potent anticancer agent for advanced researches.

关键词： Antineoplastic activity Eucalyptus extract Ehrlich ascites carcinoma cells swiss albino mice

swiss Chinese Association Explores Southwest China’s Ethnic Minority Villages

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Voice of Friendship 2014年第3期 25-28页

作者： Jing Ruoxi

A swiss Chinese Association(SCA)delegation headed by former Zurich Mayor *** Wagner visited Southwest China’s Guizhou Province in May at the invitation of the Chinese People’s Association for Friendship with Foreign Countries(CPAFFC)and to a warm welcome from provincial Governor Chen Miner and Deputy Governor Meng *** attended seminars on urban planning and vocational education in Guiyang,the provincial capital,and visited Maotai Distillery,a tea planta-

关键词： swiss provincial vocational delegation visited Wag

swiss Innovation Week 2019:Home of Drones,the New High Flyer of swiss Industry

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China's Foreign Trade 2019年第3期 58-59页

作者： Audrey 不详

Following the successful swiss Innovation Week(SIW)held in July 2018,the Embassy of Switzerland in China launches its 2nd edition from 12 to 14of June *** swiss drones as the brand-new theme,Switzerland’s drone ecosystem and innovation in the field of flying robots were *** to various rankings,Switzerland is one of the most innovative countrie s in the world and also one of the most competitive co untries.

关键词： swiss Innovation Week 2019:Home of Drones the New High Flyer of swiss Industry

A Discussion about Several Different Aspects under the Chinese Arbitration Law and the swiss Arbitration Law

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北京仲裁 2006年第4期 191-199页

作者： GU Xuan

Ⅰ. The necessity of comparison different arbitration laws The world enters into a new epoch of global economic integration. China has already today become one of the most important investment countries; on the other side, Switzerland is in face of developing a much more mature economy and broadening the economic scope. The economy and trade intercourses between the two counties will become more and more frequent. At the same time civil and commercial disputes will increase correspondingly. So it is significant to compare the arbitration systems between them for promoting the economy and trade connection between Switzerland and China.

关键词： swiss parties mediation proceedings dispute intellectual civil attempt necessity judicial

Antioxidant Activities of Ethanoilc Extracts of Spilanthes uliginosa, Ocimum basilicum, Hyptis spicigera and Cymbopogon citratus against swiss Mice Exposed to Plasmodium berghei Anka 65

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American Journal of Plant Sciences 2015年第1期6卷 64-72页

作者： K. N. Agbafor A. J. Uraku A. N. C. Okaka U. A. Ibiam P. M. Ajah O. U. Obasi Department of Biochemistry Ebonyi State University Abakaliki Nigeria Department of Biochemistry Nnamdi Azikiwe University Awka Nigeria

Malaria infection is associated with increased generation of free radicals. This study investigated the antioxidant activity of ethanolic leaf extracts of Spilanthes uliginosa, Ocimum basilicum, Hyptis spicigera and Cymbopogon citratus. Seventy two (72) swiss mice of both sexes were used. All the mice were treated intraperitoneally with 0.2 ml parasitized blood suspension and parasitemia assessed by thin blood films stained with Geimsa stain after seventy two hours. The mice were divided into six groups namely;A, B, C, D, E, and F of twelve mice each. Groups B, C, D and E were subdivided into three (3): B1, B2, B3, C1, C2, C3, D1, D2, D3, E1, E2 and E3, four in each subgroup. The subgroups were treated with the extracts of Spilanthes uliginosa (Sw), Ocimum basilicum, Hyptis spiligera and Cymbopogon citratus each for five (5) consecutive days with 200, 400 and 800 mg/kg body weight respectively via oral intubation. Two control groups, A and F were used. The negative control (A) was treated daily with 5 ml/kg normal saline while positive control group (F) was treated with 5 mg/kg body weight of chloroquine. The results indicated a general significant (P < 0.05) decrease in the lipid peroxidation concentrations of the parasitized treated mice when compared to parasitized untreated mice on the last day. A general significant dose dependent increase (P < 0.05) was observed in superoxide dismutase (SOD), catalase and glutathione perioxidase activities as well as reduced glutathione concentrations in the treated mice except at a dosage of 200 mg/kg body weight for all the plants. The effects of the extracts were significantly higher (P < 0.05) than that of chloroquine. These results suggest that the ethanolic extracts of these plants may contribute to the protection of malaria infected mice against oxidative damage by improving antioxidant status in a dose dependent manner.

关键词： Oxidative Stress Plasmodium berghei Medicinal Plants Malaria swiss Mice

一种改进型的基于双移相全桥的swiss整流器

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电工技术学报 2022年第S1期37卷 198-206页

作者：李周洋谢少军张斌锋赵鹏程南京航空航天大学自动化学院南京211100

目前,电流源型swiss整流器普遍存在硬开关与开关应力大等问题,严重影响了整流器的功率密度。为了改善高功率应用场合中的效率,该文在原有的隔离型双移相全桥swiss整流器拓扑的基础上,针对该拓扑存在的滞后桥臂软开关范围窄的问题,提出... 详细信息

目前,电流源型swiss整流器普遍存在硬开关与开关应力大等问题,严重影响了整流器的功率密度。为了改善高功率应用场合中的效率,该文在原有的隔离型双移相全桥swiss整流器拓扑的基础上,针对该拓扑存在的滞后桥臂软开关范围窄的问题,提出一种带有中点电容钳位的改进型基于双移相全桥的swiss整流器。传统全桥的滞后桥臂软开关严重依赖漏感存储能量,只能在较大负载时实现软开关,而该文提出的拓扑通过独立设计超前桥臂和滞后桥臂的变压器,使得在负载较轻时可以同时利用变压器一次侧漏感与一次侧励磁电感共同辅助滞后管寄生电容充放电,实现滞后管的软开关,而不增加过多的额外损耗。该文具体分析滞后管开关的死区时间内,电路的详细工作状态,建立各项电路参数与滞后管软开关实现之间的关系。最后通过仿真模型与样机模型验证了理论分析的正确性以及改进型拓扑的可行性。

关键词： swiss 整流器滞后管励磁电感软开关

Conception Rate Using the Select-Synch Protocol in Combination with a Lower Dose Progesterone-Releasing Intravaginal Insert (1.38 g) in swiss Dairy Cows

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Open Journal of Veterinary Medicine 2013年第1期3卷 6-10页

作者： F. Beuchat P. Berthold L. Gerber R. M. Bruckmaier A. Steiner J. Hüsler Gaby Hirsbrunner Clinic for Ruminants Vetsuisse Faculty University of Berne Berne Switzerland

Background: Synchronization programs have become standard in the dairy industry. In Switzerland, these programs are used but newly. The objective of this study was A) to estimate the pregnancy rate after a Select-Synch protocol including a low dosage of progesterone in CIDR (1.38 g). As a second step B) this pregnancy rate should be compared to cows from another swiss study that used a Select-Synch protocol with the 1.9 g insert ADDIN *** ADDIN *** (Rudolph et al., 2011). Methods: A) 196 cows were included in the study. Cows received a CIDR 1.38 g and 2.5 ml of buserelin i.m. on d 0. On d 7, the CIDR insert was removed and 5 ml of dinoprost was administered i.m. On d 0 a milk sample for progesterone analysis was taken. Pregnancy was determined at or more than 35 days after artificial insemination. B) The 1.38 g group and the 1.9 g group were compared as to cow and farm factors, number of preceding AI’s, gynecological and uterine pretreatment and treatment itself. A forward selection procedure was used (test result considered significant if p-value 0.05). Results: A) The pregnancy rate, using the Select-Synch protocol with the CIDR 1.38 g was 44.4%. B) The CIDR 1.9 g Select-Synch group revealed a pregnancy rate of 50.4% ADDIN *** ADDIN *** (Rudolph et al., 2011). Significant differences between the groups were not found. Conclusion: The 1.38 g CIDR-Select-Synch protocol may be recommended for multiparous dairy cows. The pregnancy rate compared to the 1.9 g CIDR-Select-Synch protocol was 8% lower, but this difference was not significant.

关键词： Cattle Synchronization CIDR 1.38 g Dairy swiss

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一种新的swiss型滑动主轴箱CNC车床

中国仪器仪表 1992年第1期 40-41页

作者：武少斌

墨尔本Brown & Sharp有限公司又开发出一种新的swiss型滑动主轴箱CNC车床,并首次在大阪举行的JIMTOF’90展览会上展示。这种车床的型号是SST-16,其上安装了Fanuc OTT6坐标轴的CNC装置。 SST-16的主轴箱行程为310mm,主要

关键词： CNC swiss 装置主轴箱多轴箱车床