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基于smo的永磁同步电机抖振分析及其改进

湖北汽车工业学院学报 2024年第1期38卷 60-63,75页

作者：王文波梅建伟韩文杰湖北汽车工业学院电气与信息工程学院湖北十堰442002 中国科学院高能物理研究所散裂中子源科学中心广东东莞523803

针对传统基于smo的永磁同步电机系统中存在抖振较大、观测精度差的问题,在传统smo基础上,引入了自适应增益替代固定增益,采用双曲正切函数代替传统开关函数,提出了改进型smo控制策略。在MATLAB/Simulink平台构建了系统仿真模型,对控制... 详细信息

针对传统基于smo的永磁同步电机系统中存在抖振较大、观测精度差的问题,在传统smo基础上,引入了自适应增益替代固定增益,采用双曲正切函数代替传统开关函数,提出了改进型smo控制策略。在MATLAB/Simulink平台构建了系统仿真模型,对控制策略的效果进行验证并分析。结果表明:改进后的smo控制策略显著减小了电机抖振,具备较高的转子位置估计精度。

关键词： smo 双曲正切函数自适应增益抖振

炬光科技5.8亿瑞士跨境收购落地布局汽车投影照明与AI光通信 009

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炬光科技5.8亿瑞士跨境收购落地布局汽车投影照明与AI光通信

smo Algorithm to Unravel CEED Problem using Wind and Solar

21世纪经济报道

作者：赵云帆

1月16日晚间，炬光科技（688167.SH）公告称，公司已完成对瑞士微纳光学元器件企业SUSS MicroOptics SA（下文简称“smo”）100%股权的收购。就在一天前，炬光科技披露了标的公司的收购预案，将通过购买股份并偿还标的公司向原股东的... 详细信息

1月16日晚间，炬光科技（688167.SH）公告称，公司已完成对瑞士微纳光学元器件企业SUSS MicroOptics SA（下文简称“smo”）100%股权的收购。就在一天前，炬光科技披露了标的公司的收购预案，将通过购买股份并偿还标的公司向原股东的借款，合计对价约5.86亿元人民币完成对smo

关键词：光通信微纳光学 smo

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Intelligent Automation & Soft Computing 2023年第2期35卷 1857-1872页

作者： A.Prabha G.Themozhi Rama Reddy Sathi Faculty of Electrical Engineering Anna UniversityChennai600025India Department of Electrical and Electronics Engineering AMET Deemed UniversityChennai603112India Department of Electrical and Electronics Engineering Rajalakshmi Engineering CollegeChennai602105India

This research proposes a more advanced way to address Combined Economic Emission Dispatch(CEED)concerns.Economic Load Dispatch(ELD)and Economic Emission Dispatch(EED)have been implemented to reduce generating unit fuel costs and emissions.When both economics and emission tar-gets are taken into account,the dispatch of an aggregate cost-effective emission challenge emerges.This research affords a mathematical modeling-based analyti-cal technique for solving economic,emission,and collaborative economic and emission dispatch problems with only one goal.This study takes into account both the fuel cost target and the environmental impact of emissions.This bi-inten-tion CEED problem is converted to a solitary goal function using a price penalty factor technique.In this case,a metaheuristic and an environment-inspired,intel-ligent Spider Monkey Optimization technique(smo)are used to address the CEED dilemma.By following the generator’s scheduling process,the smo meth-od is used to regulate the output from the power generation system in terms of pollution and fuel cost.The Fission-Fusion social(FFS)structure of spider mon-keys promotes them to utilize a global optimization method known as smo dur-ing foraging behaviour.The emphasis is mostly on lowering the cost of generation and pollution in order to improve the efﬁciency of the power system and han-dle dispatch problems with constraints.The economic dispatch has been reme-died,and the improved result demonstrates that the system’s performance is stable andﬂexible in real time.Finally,the system’s output demonstrates that the system has improved in resolving CEED difﬁculties.When compared to ear-lier investigations,the proposed model’sﬁndings have improved.As the gener-ating units,wind and solar are used to explore the CEED crisis in the IEEE 30 bus system.

关键词： Cost of generation emission CEED thermal power system bi-intention smo wind and solar IEEE 30 bus system

Baihui(DU20)-penetrating-Qubin(GB7) acupuncture inhibits apoptosis in the perihemorrhagic penumbra

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Neural Regeneration Research 2018年第9期13卷 1602-1608页

作者： Beng Zhang Xiao-Hong Dai Xue-Ping Yu Wei Zou Wei Teng Xiao-Wei Sun Wei-Wei Yu Hao Liu Hui Wang Meng-Juan Sun Meng Li Heilongjiang University of Chinese Medicine Harbin Heilongjiang Province China First Affiliated Hospital Heilongjiang University of Chinese Medicine Harbin Heilongjiang Province China Clinical Key Laboratory of Integrated Traditional Chinese and Western Medicine Heilongjiang University of Chinese Medicine HarbinHeilongjiang Province China Department of Acupuncture and Moxibustion Tongde Hospital of Zhejiang Province Hangzhou Zhejiang Province China

Baihui（DU20）-penetrating-Qubin（GB7） acupuncture can inhibit inflammatory reactions and activate signaling pathways related to proliferation after intracerebral hemorrhage.However,there is no research showing the relationship between this treatment and cell apoptosis.Rat models of intracerebral hemorrhage were established by injecting 60 μL of autologous blood into the right side of the caudate-putamen.Six hours later,the needle traveled subcutaneously from the Baihui acupoint to Qubin acupoint.The needle was alternately rotated（180 ± 10 turns/min） manually along clockwise and counter-clockwise directions.Stimulation lasted for 7 days,and was performed three times each for 6 minutes with 6-minute intervals between stimulations.Rats intraperitoneally receiving Sonic hedgehog pathway activator,purmorphamine（1 mg/kg per day）,served as positive controls.Motor and sensory function were assessed using the Ludmila Belayev test.Extent of pathological changes were measured in the perihemorrhagic penumbra using hematoxylin-eosin staining.Apoptosis was examined by terminal deoxynucleotidyl transferase（Td T）-mediated d UTP nick end labeling assay.Expression of smoothened（smo） and glioma-associated homolog 1（Gli1） was determined by western blot assay.Our results showed that Baihui-penetrating-Qubin acupuncture promoted recovery of motor and sensory function,reduced the apoptotic cell percentage in the perihemorrhagic penumbra,and up-regulated smo and Gli1 expression.We conclude that Baihui-penetrating-Qubin acupuncture can mitigate hemorrhage and promote functional recovery of the brain in a rat model of intracerebral hemorrhage,possibly by activating the Sonic hedgehog pathway.

关键词： nerve regeneration acupuncture treatment intracerebral hemorrhage neurological function Ludmila Belayev test TUNEL assay purmorphamine smo Ptchl Glil neural regeneration

Effect of Mono-2-ethyhexyl Phthalate on DNA Methylation in Human Prostate Cancer LNCaP Cells

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Biomedical and Environmental Sciences 2017年第9期30卷 641-648页

作者： WU Jian Hui CHEN Jiao WANG Yong XIA Bin WANG Rong ZHAO Yan WANG Qin Xia SONG Qi YAO Shun Heng ZHANG Yun Hui SUN Zu Yue National Evaluation Centre for the Toxicology of Fertility Regulating Drug Department of Pharmacology and ToxicologyShanghai Institute of Planned Parenthood ResearchShanghai 200032China Key Laboratory of Reproduction Regulation of NPFPC Shanghai 200032China Reproductive and Developmental Research Institute of Fudan University ShanghaiShanghai 200032China Division of Health Risk Factors Surveillance and Control Shanghai Municipal Center for Disease Control and PreventionShanghai 200336China Key Laboratory of Public Health Safety Ministry of EducationSchool of Public HealthFudan UniversityShanghai 200032China

Objective To evaluate whether mono（2‐ethylhexyl） phthalate（MEHP） affects genomic DNA methylation and the methylation status of some specific genes such as patched gene（PTCH） and smoothened gene（smo） in LNCaP cells. Methods LNCaP cells were treated with MEHP（0, 1, 5, 10, and 25 μmol/L） for 3 days. An ELISA assay was preformed to detect genomic methylation, including 5‐methylcytosine（5‐mC） and 5‐hydroxymethylcytosine（5‐hmC） content. A pyrosequencing assay was applied to assess DNA methylation in PTCH and smo gene promoters. The correlation between DNA methylation and gene expression was assessed. Results The proportion of cytosines with 5‐mC methylation in LNCaP cells was significantly decreased by MEHP（1, 5, 10, and 25 μmol/L） in a dose‐dependent manner（P 〈 0.01）. For genes in the Hedgehog pathway, there was no significant MEHP concentration‐dependent difference in the DNA methylation of PTCH and smo. Conclusion MEHP might affect the progression of prostate cancer through its effect on global DNA methylation.

关键词： Mono(2‐ethyhexyl) phthalate LNCaP Genomic Methylation PTCH smo

Effect of smo SiRNA-mediated Hedgehog Signaling Pathway Inhibition on Palatal Fusion

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Biomedical and Environmental Sciences 2016年第8期29卷 594-598页

作者： ZHOU Qian WU Hai Feng WEI Yuan ZHU Wen Li Department of Nutrition and Food Hygiene School of Public HealthBeijing Key Laboratory of Toxicological Research and Risk Assessment for Food SafetyPeking University Department of Urology General Hospital of Ningxia Medical University Department of Obstetrics and Gynaecology Peking University Third Hospital

We used smo siRNA to inhibit hedgehog signaling pathway in embryonic day （E） 13 palatal shelves in organ culture. SiRNA 4 was chosen as the most efficient from four synthesized smo siRNAs. Palatal shelf fusion rate of 4 Hg/mL cyclopamine group was the lowest and significantly lower than that of blank control group （P〈0.05）, and that of siRNA 4 group was also lower than that of blank control group （P=-0.183）. At 48 h after transfection,

关键词： RNA smo

smoothened regulation in response to Hedgehog stimulation

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Frontiers in Biology 2015年第6期10卷 475-486页

作者： Kai Jiang Jianhang Jia Markey Cancer Center Department of Molecular and Cellular Biochemistry University of Kentucky College of Medicine Lexington KY40536 USA

The Hedgehog （Hh） signaling pathway play critical roles in embryonic development and adult tissue homeostasis. A critical step in Hh signal transduction is how Hh receptor Patched （Ptc） inhibits the atypical G protein- coupled receptor smoothened （smo） in the absence of Hh and how this inhibition is release by Hh stimulation. It is unlikely that Ptc inhibits smo by direct interaction. Here we discuss how Hh regulates the phosphorylation and ubiquitination of smo, leading to cell surface and ciliary accumulation of smo in Drosophila and vertebrate cells, respectively. In addition, we discuss how PI（4）P phospholipid acts in between Ptc and smo to regulate smo phosphorylation and activation in response to Hh stimulation.

关键词： Hh signaling phospholipid phosphorylation smo ubiquitination signal transduction

Improving the Detection Rate of Rarely Appearing Intrusions in Network-Based Intrusion Detection Systems

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Computers, Materials & Continua 2021年第2期66卷 1647-1663页

作者： Eunmok Yang Gyanendra Prasad Joshi Changho Seo Department of Financial Information Security Kookmin UniversitySeoul02707Korea Department of Computer Science and Engineering Sejong UniversitySeoul05006Korea Department of Convergence Science Kongju National UniversityGongju32588Korea

In network-based intrusion detection practices,there are more regular instances than intrusion instances.Because there is always a statistical imbalance in the instances,it is difficult to train the intrusion detection system effectively.In this work,we compare intrusion detection performance by increasing the rarely appearing instances rather than by eliminating the frequently appearing duplicate instances.Our technique mitigates the statistical imbalance in these instances.We also carried out an experiment on the training model by increasing the instances,thereby increasing the attack instances step by step up to 13 levels.The experiments included not only known attacks,but also unknown new intrusions.The results are compared with the existing studies from the literature,and show an improvement in accuracy,sensitivity,and specificity over previous studies.The detection rates for the remote-to-user(R2L)and user-to-root(U2L)categories are improved significantly by adding fewer instances.The detection of many intrusions is increased from a very low to a very high detection rate.The detection of newer attacks that had not been used in training improved from 9%to 12%.This study has practical applications in network administration to protect from known and unknown attacks.If network administrators are running out of instances for some attacks,they can increase the number of instances with rarely appearing instances,thereby improving the detection of both known and unknown new attacks.

关键词： Intrusion detection statistical imbalance smo machine learning network security

smo和Gli1蛋白在眼睑基底细胞癌组织中的表达及临床意义

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Smo和Gli1蛋白在眼睑基底细胞癌组织中的表达及临床意义

作者：喻欣怡南昌大学

学位级别：硕士

目的:研究smo和Gli1蛋白在眼睑基底细胞癌组织中的表达情况,分析smo和Gli1的表达与眼睑基底细胞癌临床特征之间的关系,并探讨两者的相关性以及在眼睑基底细胞癌中的临床意义。方法:收集2018年至2021年期间在南昌大学第二附属医院眼科经... 详细信息

目的:研究smo和Gli1蛋白在眼睑基底细胞癌组织中的表达情况,分析smo和Gli1的表达与眼睑基底细胞癌临床特征之间的关系,并探讨两者的相关性以及在眼睑基底细胞癌中的临床意义。方法:收集2018年至2021年期间在南昌大学第二附属医院眼科经手术切除且病理诊断为眼睑基底细胞癌的病例,选取其眼睑基底细胞癌石蜡切片作为实验组,同时选取癌旁正常组织的石蜡切片作为对照组,各32例。其中男性11例,女性21例;年龄在65岁及以上18例,65岁以下14例;15例侵及眼轮匝肌层,17例侵及眶膈及眶脂肪层;肿瘤直径大于或等于2cm的12例,小于2cm的20例;肿瘤病程为2年及以上17例,肿瘤病程为2年以下15例。采用免疫组织化学染色法检测smo蛋白、Gli1蛋白在两组中的表达情况,通过Image J图形分析软件对免疫组化染色的石蜡切片进行光密度分析,计算切片中阳性颗粒表达的平均光密度值。采用SPSS 25.0软件系统进行统计学分析,以P＜0.05为差异有统计学意义。结果:1.（1）smo在眼睑基底细胞癌组织中的阳性表达率为65.68%（21/32）,在癌旁正常组织中的阳性表达率为21.88%（7/32）;实验组测得的平均光密度值为0.264±0.063,对照组的平均光密度值为0.192±0.042,经Mann-Whitney检验分析P值为0.000（P＜0.05）,smo蛋白在眼睑基底细胞癌中的光密度值大于癌旁正常组织,差异具有统计学意义。（2）Gli1在眼睑基底细胞癌组织中的阳性表达率为71.88%（23/32）,在癌旁正常组织中的阳性表达率为25.00%（8/32）,实验组测得的平均光密度值为0.271±0.067,对照组的平均光密度值为0.196±0.041,经Mann-Whitney检验分析P值为0.000（P＜0.05）,Gli1蛋白在眼睑基底细胞癌中的光密度值大于癌旁正常组织,差异具有统计学意义。2.（1）smo在肿瘤侵及眼轮匝肌层癌组织组所测得的平均光密度值为0.229±0.054,在肿瘤侵及眶膈及眶脂肪层癌组织组测得的平均光密度值为0.296±0.054,经Mann-Whitney检验P值为0.000（P＜0.05）,差异有统计学意义;smo在性别、年龄、肿瘤直径、肿瘤病程组别中表达的平均光密度值经Mann-Whitney检验P值均大于0.05,差异无统计学意义。（2）Gli1在肿瘤侵及眼轮匝肌层癌组织组所测得的平均光密度值为0.225±0.058,在肿瘤侵及眶膈及眶脂肪层癌组织组测得的平均光密度值为0.311±0.047,经Mann-Whitney检验P值为0.000（P＜0.05）,差异有统计学意义;Gli1在性别、年龄、肿瘤直径、肿瘤病程组别中表达的平均光密度值经Mann-Whitney检验P值均大于0.05,差异无统计学意义。3.Spearman相关分析表明smo和Gli1蛋白在眼睑基底细胞癌组织中的表达具有正相关性（r=0.735,P＜0.05）结论:1.smo和Gli1蛋白在眼睑基底细胞癌组织中的表达均高于对照组,差异具有统计学意义;2.smo和Gli1蛋白在眼睑基底细胞癌组织中的表达均与肿瘤侵及组织层次有关,而与性别、年龄、肿瘤直径、肿瘤病程无关;3.smo和Gli1蛋白在眼睑基底细胞癌组织中的表达正相关,两者可能协同参与眼睑基底细胞癌的发生发展。

关键词：眼睑基底细胞癌 smo Gli1 免疫组织化学法