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Compressive Myeloradiculopathies in Multiple Myeloma: Clinical and Radiological Characteristics of a Series of 29 Patients

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Open Journal of Blood Diseases 2021年第4期11卷 133-139页

作者： El Hadji Daouda Niang Mbodji Ahmadou Bamba Ka Mamadou Fall Seynabou Seck Moussa Mbaye Khalifa Ababacar Bousso Elimane Sarr Khadim Faye Atoumane Ndiaye Fatou Samba Diago Ndiaye Moustapha Diop Saliou Department of Haematology Cheikh Anta Diop University Dakar Senegal Department of Neurology Cheikh Anta Diop University Dakar Senegal Internal Medicine Service Aristide Le Dantec Hospital Cheikh Anta Diop University Dakar Senegal

Introduction: Patients with multiple myeloma (MM) develop neurological complications such as root and/or spinal cord compression in at least 5% of cases. The aim of this work is to describe the clinical and radiological features of root and/or spinal cord compression occurring during multiple myeloma. Patients and Methods: We conducted a retrospective study in the Clinical Haematology Department of Dalal Jamm Hospital and the National Blood Transfusion Centre, the Neurological Clinic of Fann Hospital Centre and the Internal Medicine Department of Aristide Le Dantec Hospital in Dakar between January 2016 and December 2019. All patients whose multiple myeloma diagnosis was established according to the International Myeloma Working Group’s 2014 and who had root, spinal or myeloradicular compression, were included in our study. Results: A total of 29 patients were included. The average age was 54.31 years [32 - 76 years]. The sex ratio (M/F) was 1.6. Motor deficits were the reason for consultation in 68% of the patients and spinal pains were reported by 93% of the patients. Neurological signs revealed multiple myeloma in all our patients. 25 patients (86.2%) had paraplegia and 1 patient had tetraparesis. Hypoesthesia to a defined sensory level was noted in 8 patients (28%). 5 patients (17.24%) had sphincter disorders. The types of lesions showed by imaging were vertebral lysis in 100% of cases, vertebral compression in 37% of cases, and epidural infiltration in 34% of cases. 12 patients (41.37%) had spinal compression, 14 patients (48.27%) had root compression, and 3 patients (10.34%) had my

关键词： Multiple Myeloma Spinal Cord compression root compression Bone Lesions

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UTILITY OF ELECTRODIAGNOSTIC TESTING IN EVALUATING PATIENTS WITH LUMBOSACRAL RADICULOPATHY:AN EVIDENCE-BASED REVIEW

UTILITY OF ELECTRODIAGNOSTIC TESTING IN EVALUATING PATIENTS ...

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中国康复医学会电诊断专业委员会换届暨学术研讨会

作者： S.CHARLES CHO MARK A.FERRANTE KERRY H.LEVIN ROBERT L.HARMON YUEN T.SO Stanford University School of Medicine Ohio State University School of Medicine Cleveland Clinic ClevelandOhioUSA MD Pain Management and Rehabilitation Specialists PC and Medical College of Georgia

＜正＞This is an evidence-based review of electrodiagnostic （EDX） testing of patients with suspected lumbosacral radiculopathy to determine its utility in diagnosis and prognosis. Literature searches were performed to identify articles applying EDX techniques to patients with suspected lumbosacral radiculopathy. From the 355 articles initially discovered.119 articles describing nerve conduction studies,electromyography（EMG）, or evoked potentials in adequate detail were reviewed further. Fifty-three studies met inclusion criteria and were graded using predetermined criteria for classification of evidence for diagnostic studies.Two classⅡ,7 classⅢ.and 34 classⅣstudies described the diagnostic use of EDX.One classⅡand three classⅢarticles described H-reflexes with acceptable statistical significance for use in the diagnosis and confirmation of suspected S1 lumbosacral radiculopathy.Two classⅡand two classⅢstudies demonstrated a range of sensitivities for use of muscle paraspinal mapping.Two classⅡstudies demonstrated the utility of peripheral myotomal limb electromyography in radiculopathies.

关键词： electrophysiology herniated disk lumbosacral radiculopathy lumbosacral radiculitis low back pain root compression sciatica

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